1may be defined as an agent or substance, intended for use in the diagnosis, mitigation, treatment, cure or prevention of disease in human beings or animals.
Drugs
2rarely administered in their original or crude forms.
Drugs
3the carrier through which drug molecules are delivered to sites of action
within the body.
Dosage forms
4Every dosage forms is a combination of the drug and
different kinds of non – drug components called as
Excipients or additives.
5one of the oldest dosage forms and most of it are available in Unit dose.
Solid dosage forms
6Solid dosage forms are most available in
Unit dose
7What dosage form to use when drugs are administered orally in dry state
Tablets and Capsules
8supplied in bulk (Means quantity available in large)
Solid dosage forms
9can be supplied as Internal (Granules, Fine powders) as well as External (Dusting Powders, Insufflations etc)
Bulk powders
10are prepared agglomerates of smaller particles of powders.
For better flow ability and compressibility of powders
GRANULES
11are mixture of finely divided drugs or chemicals in dry form which can be used internally or externally.
POWDERS
12are applied externally to skin, so they should be applied in very
fine state to avoid local irritation.
Dusting Powders
13are prepared by mixing of more than one ingredients in which either starch, kaolin, or talc are used in their formulation
Dusting powders
14Used generally in dusting powders because they are inert in nature
Talc or kaolin
15are used for antiseptic, astringent, absorbent, antiperspirant etc.
Dusting powders
16Dusting powders are of two sub type they are as
Medical dusting powder
Surgical Dusting powders
17are used to increase superficial condition of skin.
▪ These are NOT applied on wounds, burns etc
Medical dusting powder
18must be free from dangerous pathogenic micro- organism.
Medical dusting powders
19are used in body cavities and also on major wounds like as burns etc.
▪ They should be sterilized before use.
▪ They are mainly used for their antiseptic, absorbent action.
Surgical dusting powders
20It sprays the powders (in a state of fine particles) on site of application.
Insufflations
21These are medicated dusting powders meant for introduction into body
cavities (nose, throat, ear, vagina etc)
Insufflations
22Insufflations is introduced to the body with the help of the apparatus known
insufflator
23These are finely divided solid dosage forms of medicaments which are
inhaled into nostrils
Snuffs
24is the process in which primary powder particles are made to
adhere to form larger multiparticle or large particles entities called granules
Granulation
25The bitter, nauseous, unpleasant powders can not be given tablets,
capsule due to
bulk quantity
26not given in liquid dosage forms due to their stability such powders are given in the
granules forms.
27Example of granules
Effervescent
28Meant for internal use. They contained medicaments mixed with
citric acid, tartaric acid & sodium bicarbonates, sometime saccharin or
sucrose may be added for sweetening taste.
Effervescent granules
29Added for sweetening taste
saccharin or sucrose
30These are solid dosage forms of medicaments which are prepared by molding or by compression with or without excipients
Tablets