DOSAGE FORMS PART 1

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1
may be defined as an agent or substance, intended for use in the diagnosis, mitigation, treatment, cure or prevention of disease in human beings or animals.
Drugs
2
rarely administered in their original or crude forms.
Drugs
3
the carrier through which drug molecules are delivered to sites of action
within the body.
Dosage forms
4
Every dosage forms is a combination of the drug and
different kinds of non – drug components called as
Excipients or additives.
5
one of the oldest dosage forms and most of it are available in Unit dose.
Solid dosage forms
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Solid dosage forms are most available in
Unit dose
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What dosage form to use when drugs are administered orally in dry state
Tablets and Capsules
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supplied in bulk (Means quantity available in large)
Solid dosage forms
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can be supplied as Internal (Granules, Fine powders) as well as External (Dusting Powders, Insufflations etc)
Bulk powders
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are prepared agglomerates of smaller particles of powders.
For better flow ability and compressibility of powders
GRANULES
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are mixture of finely divided drugs or chemicals in dry form which can be used internally or externally.
POWDERS
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are applied externally to skin, so they should be applied in very
fine state to avoid local irritation.
Dusting Powders
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are prepared by mixing of more than one ingredients in which either starch, kaolin, or talc are used in their formulation
Dusting powders
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Used generally in dusting powders because they are inert in nature
Talc or kaolin
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are used for antiseptic, astringent, absorbent, antiperspirant etc.
Dusting powders
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Dusting powders are of two sub type they are as
Medical dusting powder
Surgical Dusting powders
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are used to increase superficial condition of skin.
▪ These are NOT applied on wounds, burns etc
Medical dusting powder
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must be free from dangerous pathogenic micro- organism.
Medical dusting powders
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are used in body cavities and also on major wounds like as burns etc.
▪ They should be sterilized before use.
▪ They are mainly used for their antiseptic, absorbent action.
Surgical dusting powders
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It sprays the powders (in a state of fine particles) on site of application.
Insufflations
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These are medicated dusting powders meant for introduction into body
cavities (nose, throat, ear, vagina etc)
Insufflations
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Insufflations is introduced to the body with the help of the apparatus known
insufflator
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These are finely divided solid dosage forms of medicaments which are
inhaled into nostrils
Snuffs
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is the process in which primary powder particles are made to
adhere to form larger multiparticle or large particles entities called granules
Granulation
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The bitter, nauseous, unpleasant powders can not be given tablets,
capsule due to
bulk quantity
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not given in liquid dosage forms due to their stability such powders are given in the
granules forms.
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Example of granules
Effervescent
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Meant for internal use. They contained medicaments mixed with
citric acid, tartaric acid & sodium bicarbonates, sometime saccharin or
sucrose may be added for sweetening taste.
Effervescent granules
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Added for sweetening taste
saccharin or sucrose
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These are solid dosage forms of medicaments which are prepared by molding or by compression with or without excipients
Tablets
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