A+P 1 Quiz 4

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1
What are the 5 functions of the skeletal system?
Support, Protection, Movement, Hematopoiesis, and Mineral Storage.
2
How does the skeletal system protect the organism?
There are bones around the brain (skull bones) that protect it from non-traumatic injury, as well as bones around the heart and lungs (thoracic cage) that protect them.
3
What is hematopoiesis?
The process of creating red blood cells (RBC) and white blood cells (WBC).
4
What are the two types of bone marrow?
Red Bone Marrow (RBM) and Yellow Bone Marrow (YBM).
5
What does red bone marrow do?
RBM creates blood cells. It is where hematopoiesis takes place.
6
What does yellow bone marrow do?
YBM stores fat.
7
Where can red bone marrow be found? (Which specific bones?)
RBM can be found in the skull, thoracic cage, spine, and pelvis.
8
Where can yellow bone marrow be found? (Which specific bones?)
YBM can be found in the extremities; all of the bones that make up the arms, legs, hands, and feet.
9
Children are born having bones that have only...
  • Yellow Bone Marrow
  • Red Bone Marrow
10
At what age do humans have all of their yellow bone marrow developed?
25 years old.
11
What is an osteogenic cell? What is the function of an osteogenic cell?
An osteogenic cell is a stem cell. An osteogenic cell eventually develops into an osteoblast.
12
What is an osteoblast? What does an osteoblast have the potential to turn into?
An osteoblast is a cell that forms bones (they lay down bone matrix and collagen fibers [osteoid tissue]). Osteoblasts will eventually develop into osteocytes.
13
What is an osteocyte?
An osteocyte is a mature bone cell.
14
What is an osteoclast? What is their purpose.
An osteoclast is a cell that destroys bone. They break down bone in the process of bone remodeling, and they also release calcium.
15
What bone type has an epiphysis and diaphysis?
The long bones.
16
What part of the bone is the epiphysis?
The ends of the long bone.
17
What part of the bone is the diaphysis?
The mid section of the long bone.
18
What is articular cartilage?
It is hyaline cartilage that covers the epiphysis of long bones.
19
An epiphyseal line is the ossified remains of what? What was the purpose of the original structure?
The epiphyseal plate. The purpose was to facilitate growth of bones in childhood development.
20
Where can the medullary cavity be found?
In the mid section of the bone, the core in other words. (Also described as being located in the diaphysis.)
21
What are the 7 main structures of compact bone?
Osteons, bone lamellae, osteocytes, lacunae, canaliculi, central canals, and perforating canals.
22
What is an osteon?
A unit of compact bone.
23
What is the bone lamellae? What does it contribute to the compact bone?
The bone lamellae are concentric layers of compact bone. They creates a strong bone that is against bending or breaking.
24
What is a lacuna?
This is where osteocytes live within the bone matrix.
25
What is a canaliculi? What is its purpose?
They are little tunnels between the Lacunas, for the osteocytes to be able to communicate amongst themselves.
26
What passes through central and perforating canals?
Blood vessles and nerves.
27
What is spongey bone composed of?
They are composed of weaved layers of trabeculae.
28
What is stored in the trabeculae of spongey bone?
Osteocytes.
29
What passes through the gaps of the trabeculae within spongey bone?
Red bone marrow and blood vessles.
30
What is the periosteum of the bone?
The periosteum forms the outer surface of the bone.
31
What is the endosteum of the bone?
The endosteum lines the inner surface of the medullary cavity.
32
Which direction of bone growth is interstitial growth?
It is growth in length.
33
Which direction of bone growth is appositional growth?
It is growth in width.
34
In interstitial growth, where does the growth occur at originally?
The epiphyseal plate.
35
What are the 4 main stages of interstitial growth?
Reserve, proliferation, maturation/hypertrophy, and calcification.
36
Define: Chondrocytes
Produces and maintains the cartilaginous matrix. Essentially produces cartilage.
37
Define: Proliferation
Chondrocytes are dividing via mitosis.
38
Define: Maturation/Hypertrophy
Chondrocytes are expanding rapidly which makes the bone expand.
39
What happens to get to the stage of a "calcified matrix"?
Chondrocytes die and osteoblasts replace them with a bony matrix.
40
What is the purpose of calcium homeostaisis?
To regulate the amount of calcium in the blood stream.
41
What hormone is released when calcium levels DROP? What is the osteoclast response?
Parathyroid is the hormone released. Osteoclasts begin releasing more clacium into the blood stream.
42
What hormone is released when calcium levels RISE? What is the osteoclast response?
Calcitonin is the hormone released. This hormone inhibits the osteoclasts from releasing calcium.
43
Where does calcitonin come from?
The thyroid glands.
44
A patient comes in with a prior diagnosis of Osteoporosis. What is the result of this disease in the bones and how could you expect for this to manifest in the patient's life?
Osteoporosis causes the compact bone to be less dense, which will manifest as brittle bones. The patient my often have fratures or breaks.
45
What are the 4 stages of a frature repair?
A hematoma forms, a callus is formed from cartilage, the cartilage of the callus is replaced by trabecular bone, remodeling occurs.
46
What is intramembranous ossification?
It is when bone develops from mesenchymal tissue (a type of embryonic connective tissue).
47
Why type of bones are formed from intramembranous ossification?
This forms the flat bones, which are bones of the skull pelvis, sternum. And it also forms the clavicles.
48
What are the basic steps to intramembranous ossification? There are about 10 steps.
Mesenchymal Cells group into clusters -> Forms osteoblasts -> Creates ossification centers -> Osteoblasts make osteoid tissue -> Forms trabeculae and makes a woven pattern intertwined around blood vessels -> Osteoid tissue traps osteoblasts -> Creates more osteocytes -> Matrix ossifies -> Compact bone develops around the trabeculae (spongy bone) -> The blood vessles in the trabeculae develops into red bone marrow.
49
What is endochondral ossification?
It is when bone slowly replaces hyaline cartilage that is found in the epiphyseal growth plate of bones. All of the other bones are formed this way.
50
What are the steps to endochondral ossification? There are about 12.
Mesenchyme cells -> Osteoblasts -> Creates the bony collar -> Bony collar restricts blood flow to chondrocytes -> Chondrocytes die and break down -> Blood vessles invade the cavity -> Osteogenic cells enter the cavity -> Osteoblasts replace the chondrocytes with a matrix to form spongey bone -> Osteoclasts will break down and form the medullary cavity -> Blood vessels will enter the ends of the long bones which makes the secondary ossification center -> Osteoblasts will lay down spongy bone (middle to outside)-> Hyaline cartilage remains around the ends of the bone which makes articular cartilage and remains in the epiphyseal plate.
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