Anicocytosis

refers to the increased number of red cells with variation in size.

Normal RBCs (normocytes) measure between these diameters.

Normal RBCs (normocytes) are usually seen when the MCV is in this range.

RBCs that are larger than normal with a diameter > 8.0 um are called.

Macrocytes are usually seen when the MCV value is.

Macrocyte formation is associated with this specific physiological impairment.

RBCs that are smaller than normal with a diameter < 6.0 um are called.

Microcytes are usually seen when the MCV value is.

Microcyte formation is associated with this specific formation defect.

List the four ways to detect anisocytosis.

In a peripheral blood smear (PBS), the size of an RBC is compared to the nucleus of this specific cell.

This value represents the average volume of individual RBCs.

Provide the formula for calculating MCV.

Reference range for MCV.

Generally, a decreased MCV indicates this.

Generally, an MCV within the 80-100 fL range is considered.

Generally, an increased MCV indicates this.

Visual display of cell size on the X-axis and cell frequency or number of cells on the Y-axis.

Automated hematology analyzers produce histograms for these three cell types.

Name the two parameters calculated from an RBC histogram.

Instruments count cells as RBCs when they fall between these volume sizes.

RBC histograms can measure cells as small as this volume.

Cells in the 24 to 36 fL range are not included in this measurement.

These cells are present in diluted fluid but are statistically insignificant in the RBC count.

If the RBCs are macrocytic, the histogram curve will.

If the RBCs are microcytic, the histogram curve will.

This term describes a histogram curve indicating two distinct populations of RBCs in a sample.

Calculated index from the RBC histogram used to help identify anisocytosis and provide information about its degree.

Two methods provided by most recent hematology analyzers to calculate RDW.

Method based on both the width of the RBC distribution curve and the mean RBC size.

Method based on the actual measurement of the width of the RBC distribution curve in fL (femtoliters).

Reference range for RDW-CV in adults.

Reference range for RDW-SD in adults.

Earliest method provided by hematology analyzers to measure red cell variations.

RDW calculation method that is dependent on the width of the distribution curve and the MCV.

Point on the RBC distribution curve where the width for RDW-SD is measured.

The RDW-SD is considered a better and more reliable measure of erythrocyte variability because it is not influenced by this value.

RDW calculation method preferred for highly abnormal conditions.

Derivation of RDW-CV is associated with these two specific corporations.

Reference range for RDW in newborns.

Expected trend of RDW values in newborns as they grow.

Age at which a newborn's RDW value typically reaches adult levels.

Description of the RDW value if the RBC histogram is wider than normal.

Condition associated with Normal RDW and Decreased MCV (microcytic).

Condition associated with Normal RDW and Normal MCV (normocytic).

Condition associated with Normal RDW and Increased MCV (macrocytic).

Condition associated with Increased RDW (anisocytosis) and Decreased MCV (microcytic).

Condition associated with Increased RDW (anisocytosis) and Normal MCV (normocytic).

Condition associated with Increased RDW (anisocytosis) and Increased MCV (macrocytic).