m10 finals

An undesirable event
experienced by a patient that involves or is suspected to
involve drug therapy and actually or potentially interferes
with a desired patient outcome

5 classifications of Medication-Related Problem (MRP)

is a response to a drug that is
noxious and unintended and occurs at doses normally used in
man for the prophylaxis, diagnosis or therapy of disease, or
for modification of physiological function.

An
unpleasant
effect
of
a drug, medical treatment, or vaccine
that happens in addition to the desired action
or intended effect

reactions result from an exaggeration of a
drug’s normal pharmacological actions when given at the usual therapeutic
dose and are normally dose-dependent.

example of Type A Reactions [Augmented]

also include those that are not directly related to the
desired pharmacological action of the drug, for example dry mouth that is
associated with tricyclic antidepressants.

accentuate the activity
of inhibitory neurons in the
brainstem and decrease the
respiratory rate and tidal volume.

also decrease
the
ventilatory
response to
hypoxia and hypercapnia

is
an
oral
anticoagulant
commonly
used
to
treat
and
prevent
blood
clots.

has
multiple
FDA-approved and offlabel clinical uses.

are novel responses that are not
expected from the known pharmacological actions of the drug. These are
less common, and so may only be discovered for the first time after a drug
has already been made available for general use

examples of Type B Reactions [Bizarre] reactions

persist for a relatively long time

examples of Type C Reactions [Continuing] reactions,

are a group of
drugs that work by slowing bone
loss.

become apparent some time after the use of
a medicine. The timing of these may make them more difficult to detect.

example of Type D Reactions [Delayed],

An alkylating agent used as a part
of chemotherapeutic regimens for
the treatment of primary and
metastatic brain tumors

are associated with the
withdrawal of a medicine.

examples of Type E Reactions [End-of-use] reactions