1What is disease classification of Gastroenteritis?
(intestional infection)
2What causes Gastroenteritis?
*Escherichia coli (E. coli)
3How many pathogenic variants of Escherichia coli (E.coli) exists?
*6 pathogentic variants
4Name of shiga toxin producing E. coli strain?
E. coli 0157: H7 (STEC)
5Characteristics of Escherichia coli:
*gram negative bacillus
*facultative anaerobe (doesn't need oxygen)
*motile
*non-spore forming
6Epidemiology of Escherichia coli?
*reservoir: animals and their environment
*portal of entry: digestive tract
*Mode of Transmission: fecal oral route
7Incubation period of Escherichia coli?
*1-3 days
8Pathogenesis of Escherichia coli?
*process varies slighly depending on the ecoli strain
*includes colonization of small or large intestine by attatching/invading epithelial cells
9Pathogenesis of O157: H7 E. coli?
*attaches to the linning of colon and forms diarrhea inducing lesions
*can secrete shiga toxins
10What do shiga toxins do? What releases them?
*damage blood vessles resulting in intestional hemmorrhage
*released by 0157:H7 Escherichia coli
11Signs and Symptoms of E.coli?
*diarrhea (often blood without pus)
*abdominal craps
*fever
*nausea
*vomiting
12When do symp start to improve for those with Gastroenteritis?
3-10 dys
13Complications of Gastroenteritis?
*severe dehydration
*Hemolytic-uremic syndrome (HUS)