PTCB Definitions

13 flashcardsby gardneae
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1
absorption
drug gets absorbed into the bloodstream
2
distribution
drug goes to where it is needed
3
metabolism
drug is broken down by the liver
4
comminution
act of breaking down a material into small particles (what mortars do)
5
levigation
grinding an insoluble substance to a fine powder while it is we to create a thin paste (done with mortar)
6
trituration
grinding a substance to a fine particle size
7
punch method
method used to fill capsules: https://www.youtube.com/watch?v=ZObwo14mTdI
8
drug titration
act of changing the dose to achieve the best clinical response (done with mortar)
9
elimination
excretion from the body
10
dissolution
must be dissolved in stomach before it can elicit its pharmacological effect
11
effervescence
release of carbon dioxide gas (active ingredient + sodium bicarbonate + citric acid or tartaric acid leads to acid and base reaction)
12
first pass effect
drug is broken down by the liver or another site before it reaches the rest of the body
13
alligations
old and practical method of calculating the amount of ingredients needed to make a specific strength
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