blood loss/blood clots

35 Karteikartenvon Brittany
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1
Term for the stoppage of bleeding or hemorrhage
Hemostasis
2
3 mechanisms for reducing blood loss
1 vascular spasm
2 platelet plug formation
3 blood clotting
3
Which mechanism for reducing blood loss involves platelets binding to exposed collagen in blood vessel wall. Can stop bleeding from small blood vessel
Platelet plug adhesions
4
Which mechanism for reducing blood loss involves Vasoconstriction? Vasoconstriction is due to damage to smooth muscle, substance released by activated platelets, reflexes stimulated by pain receptors.
Vascular spasms
5
Step 1: in formation of clot; in formation of clot damaged tissue and platelets release factors that stimulate series of reactions that results in formation of this molecule

Damaged tissue and platelets release factors that stimulate series of reactions that result in formation of this molecule.
Formation of prothrombin activator (PTA)
6
Step 2 in formation of clot: prothrombin is a plasma protein produced in liver
Prothrombin activator converts prothrombin into the enzyme thrombin 
7
Step 3 in formation of clot : fibrinogen is plasma proteins produced by liver

Thrombin converts soluble fibrinogens(in plasma) into insoluble fibrin
8
Step 4 in formation of clot
Fibrin mesh traps cells to forma clot which strops blood flow
9
Vitamin required for normal blood clotting. Fat soluble vitamin produced in large intestine. Dietary lipids needed for adequate absorption to prevent uncontrolled bleeding
Vitamin K 
10
Mineral essential for the clotting process
Calcium ions
11
Term for dissolution of blood clots. Prevents clots from extending beyond site of damage and prevents small clots from becoming large clots
Fibrinolysis
12
Plasma protein involved in clotting. This protein is an inactive enzyme.
Plasminogen
13
Converts plasminogen to plasmin. Released when endothelium is damaged.
Tissue plasminogen
14
Enzyme that digests fibrin and other substances that promote clotting.
Streptokinase(streptase)
15
A antigen on RBC surface.
Type A blood & AB
16
B antigen on RBC surface.
type B & AB
17
Anti-A antibody in blood.
Type B & O
18
Anti-B antibody in blood.
Type A & O
19
Blood type that is universal donor
O
20
Blood type that is universal recipient
AB
21
True or False. Rh+ individual has Rh antigen on RBCs
true
22
True or False. Normally, Rh- individuals do not have anti-Rh antibodies in blood
False
23
Name for disease of newborn that occurs if Rh+ baby is born to Rh- mother with anti-Rh antibodies. Anti-Rh antibodies are present because blood from previous Rh+ child contacts mother’s blood during birth
Hemolytic disease of newborn(HDN)
24
Loss of blood decreases blood volume Manifestations
Low BP
25
Rupture of blood vessels and reduced clotting in GI tract (including mouth) or urinary tract. Manifestations
Blood in poop or pee
26
Bleeding into joints. Causes swollen, red, painful joints

Manifestations
Hemarthrosis
27
Vomiting blood

Manifestations
Hematemesis 
28
Decreased RBC count due to bleeding Manifestations
Anemia
29
CNS hypoxia due to decreased blood flow and therefore oxygen to brain Manifestations
Faint and anxious
30
Coughing up blood Manifestations
Hemoptysis
31
Cardiac compensatory mechanism for low blood pressure

Manifestations
Rapid pulse
32
Nosebleeds Manifestations
Repeated epistaxis
33
Red or purple discolorations on skin that do not blanch when applying pressure. Due to bleeding from small blood vessels near surface of skin. Manifestations
Purpura
34
Red or purple discolorations on skin that are less than 3 mm in diameter Manifestations
Petechiae
35
Red or purple discolorations on skin that are greater than 1 cm in diameter. Manifestations
Ecchymosis
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