Hospital lec

special committee created to ensure that all drug products to be used in a hospital are safe, effective, quality and affordable.

A legal framework which requires hospital and other health facilities to have Pharmacy and Therapeutics committee for liscensing purpose

serves as the organizational line of communication between the medical staff and pharmacy department

A policy-recommending body to the medical staff and the administration of the hospital on matters related to the therapeutic use of drugs

The pharmacy and therapeutics committee composed of:

A chairman from among the physician representatives should be appointed. The chief pharmacist usually is designated as secretary

Minutes of the committee meetings should be prepared by the secretary and maintained in the partial records of the hospital

The committee shall meet regularly at least three times a year and when necessary

the most appropriate body to develop drug policies within a hospital or group of health facilities

Recommends adoption of policies regarding the evaluation, selection, deletion, and therapeutic use of drug products

Develops and constantly updates the hospital formulary based on the latest edition of the PNF and on evaluated and selected drug products to be used by the hospital

Implements Hospital Formulary System

important function of a PTC

Requests authority to procure drug products not included in the current edition of the PNF

systematically developed statements that assist prescribers in deciding on treatments for specific clinical problems

They usually reflect the consensus on the optimal treatment options within a health system and aim at beneficially influencing prescribing behavior or at all levels of care

Monitoring indicators of medicine use, including adherence to standard treatment guidelines

Monitoring adverse drug reactions and medication errors

Drug use evaluation (DUE) also known as

Collects and reviews ADR/ADE reports for submission in compliance to DOH AO No. 2011-0009 National Policy and Program on Pharmacovigilance

Develops and disseminates educational materials and programs relative to drug products to all concerned hospital staff

Reports committee composition every two (2) years and submits semiannual accomplishment report to the chief of the hospital administration and to the Policy Planning and Advocacy Division (PPAD)

Report shall also be submitted to the Food and Drug Administration (formerly the Bureau of Food and Drugs or BFAD) every 20th day of February and November (per DOH AO 107 s. 2000)

approved by the Food and Drug Administration for testing in humans for a specified condition but not approved for commercial marketing and sale because its safety and effectiveness has not been approved.

defined as an authorized, structured, ongoing review of prescribing, dispensing and use of medication

a comprehensive review of patients’ prescription and medication date before, during and after dispensing to ensure appropriate medication decision-making and positive patient outcomes

play a key role in helping managed health care systems understand, interpret, evaluate, and improve the prescribing administration and use of medications

intentional or unintentional incorrect use of medication

prescribed
drug should not be used with certain disease

when two or more different drugs interact and alter their intended effects, often causing adverse events putting the patient at risk

due to age, allergies, gender, pregnancy etc.

therapeutic interchange, generic substitution

when the dosage prescribed does not comply with the accepted standards to achieve a therapeutic effect

The DOH provides the institutional authority for the formulary system of drug-use control as well as the mechanism for the continuing education of physicians,
nurses and pharmacists.

World Health Organization defines Adverse Drug Reaction as any unexpected, unintended, undesired or excessive response to a drug. Whereas, (ASHP) defines adverse drug reaction as any response to a drug which is noxious and unintended, and which occurs at doses normally used in man for prophylaxis, diagnosis or therapy of disease, or for the modification of physiological function.

 Common Dose dependent
 Predictable
 Includes side effects and extended effects
 Can be corrected by dose adjustment