LEC 19 BIOL 431

Uses hormones
effect is slow but long lasting

Exocrine - secrets into ducts > external environment
endocrine - secrets into ECF > circulatory system

Pitutary
thymus
thyroid
parathyroid
adrenal
pineal

Insulin

erythropoietin, Renin

Gastrin
secretin

CCK - cholecystokinin

Regulate:
fluid balance, glandular activity, metabolism, immune system, muscle contraction

alter cell perm
stim synthesis of protein and hormones
de/activate hormones
stim secretion
mitosis

fat soluble = steroids
water soluble = Amino acid based

hormone finds surface receptor passes to 2nd messenger (cAMP) passes message to receptor in nucleus the effects
effects = stim of secretion, change in perm

hormones diffuse through membrane where they attach to receptor > enter nucleus > effects on DNA
effect = gene on/off

amino hormones = nor/epinephrine
peptide hormones = ADH ( short chain of amino acids)
protein hormones = insulin, growth hormone

the blood is constantly monitored by the hypothalamus and the secreting organs fore changes in the blood chemical comp.

up regulation is when the amount of receptor on a cell is increased therefore making the cell more sensitive to that hormone.

when the amount of receptor on a cell decreases due to prolong exposure to hormones

Anterior lobe (75%) = makes hormones based on communication through hypophyseal portal system to hypothalamus
posterior lobe = releases Nero hormones from axons and store sythesizd hormones

Posterior pit gland and infundibulum
produces = ADH and oxytocin

Antidiruteuc hormone = stim water reaborption prevents dehydration
ALSO increase bp by vasoconstriction
ETOH inhibits the production

Stim contraction of the uterus due to distention
stim of hormone by stim of nipple for milk ejection
provides nurturing feeling

estrogen testosterone progesterone cortisol