LEC 14 BIOL 431
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1
What are the 3 methods of transport for CO2?
Dissolved 7-10%
bound to hb 20-30%
Bicarbonate ions 60-70%
bound to hb 20-30%
Bicarbonate ions 60-70%
2
What is the name for hb bound to CO2?
carbaminohemoglobin
3
What is the catalyst for the reaction in bicarbonate ions?
carbonic anhydrase
4
What is the Haldane effect?
The effect of decreased PO2 and hb saturation = higher affinity for CO2
5
What is the Bohr effect?
The effect of pH on O2 affinity to hb
6
What are the 3 types of controllers of ventilation ?
Sensors
central controller
effectors
central controller
effectors
7
What are the 4 receptors ?
Centeal chemoreceptors
Peripheral chemoreceptors
stretch receptors
Irritant recceports
Peripheral chemoreceptors
stretch receptors
Irritant recceports
8
What do the central chemoreceptors do and where are they found?
Respond to changes in pH, VENRTRAL surface of medulla
9
What is hypercapnia>
Increase in rate and depth of breath
10
What are the Peripheral receptors?
increased vent due to artieral hypoxia
carotid sinus 9
aortich arch 10
carotid sinus 9
aortich arch 10
11
What are stretch receptors?
also called barorecpetors, keeps lung from overfilling, stimulates inspiratory muscles
12
What are the two parts of the central controller and what are there rolls?
Ventral respiratory group (VSG) = Eupnea - (12-15 bpm) pacemaker
Dorsal respiratory group (DSG) = receives it for from peripheral receptors and modifies VRG based on info
Dorsal respiratory group (DSG) = receives it for from peripheral receptors and modifies VRG based on info
13
What is the pontine respiratory center?
Pneumotaxic center = controllable
Apneustic center = automatic
Apneustic center = automatic
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