Salmonellosis
Réviser ces flashcardsGratuit · répétition espacée · iPhone, Android, Mac et web
Toutes les cartes
1
Disease Type?
*Salmonellosis (gastroenteritis)
*Typhoid Fever
*Typhoid Fever
2
How does it appear on HEA plates?
appears black on plate
3
CO?
*Salmonella enterica and bongori
4
What are the NTS (non-typhoid salmonella) types?
S. typhimurium
S. enteritidis
S. enteritidis
5
What are typhoid versions of Salmonella enterica?
*S. typhi (CT 18 or Ty2)
*S. paratyphi
*S. paratyphi
6
What type of secretion system does it use?
Type 3 secretion system, inserts itself, is not digested by lyzosome
7
Classification?
*gram negative motile rod
*fimbria attatchment to epitheila
*intracellular parasite
*Type 3 secretion system
*H2S production (black on HEA plate)
*fimbria attatchment to epitheila
*intracellular parasite
*Type 3 secretion system
*H2S production (black on HEA plate)
8
How many serotypes?
*2500+ types
9
What does it secrete as an intracellular parasite?
invasins
10
Reservoir?
humans
11
POI?
digestive tract
12
MOT?
oral route, ingestion of contaminated foods (eggs) and water
13
Incubation period
12-48 hrs
14
Pathogenesis?
*bacteria attatches to the surface of small intestine, invades epithelial and immune cells.
*certain strains produce enterotoxins
*certain strains produce enterotoxins
15
What are the effects of enterotoxins?
*dysentery
*hemolytic-uremic syndrome (shiga toxins)
*hemolytic-uremic syndrome (shiga toxins)
16
Describe the type 3 secretion system for Salmonella:
*endocytosis
*mutliplication within vesicle (evades lyzosomes)
*lysis and escapes cell
*mutliplication within vesicle (evades lyzosomes)
*lysis and escapes cell
17
What are the symptoms?
*gastroenteritis
*fever
Diarrhea (loose, moderate volume, no blood)
*fever
Diarrhea (loose, moderate volume, no blood)
18
Symptom duration?
resolves in 4-5 dys
carriage (4-5 weeks) carrying the organism but not manifesting the symptoms
carriage (4-5 weeks) carrying the organism but not manifesting the symptoms
19
Complications of Gastroenteritis?
*severe dehyration
*worsening of pre-existing conditions
*bacteremia
*localized infections
*chronic carrier state
*reactive arthritis
*worsening of pre-existing conditions
*bacteremia
*localized infections
*chronic carrier state
*reactive arthritis
20
Symptoms of Enteric (typhoic fever) version of salmonella:
*headache
*weakness
*loss of appetite
*coated tongue
*cough
*abdominal pain
*diarrhea or constipation
*rashes
*weakness
*loss of appetite
*coated tongue
*cough
*abdominal pain
*diarrhea or constipation
*rashes
21
What strains lead to Enteric (typhoic fever)?
*S. typhi
*S. paratyphil
*S. paratyphil
22
What is incubation period of Enteric (typhoid fever)?
1-2 weeks
23
What is the key symptom of Enteric (typhoid fever)?
*prolonged high fever (103-104 F for 3-4 weeks)
24
Symptoms of Enteric (typhoid fever)?
*headache
*weakness
*loss of appetite
*coated tongue
*cough
*abdominal pain
*diarrhea or constipation
*rash (less than 5 % of cases)
*weakness
*loss of appetite
*coated tongue
*cough
*abdominal pain
*diarrhea or constipation
*rash (less than 5 % of cases)
25
What are the complications of Enteric (Typhoid Fever)?
*intestional hemorrhage (10% of cases)
*intestional perforation (3%)
*tissue necrosis
*tissue necrosis
*infection of other organ systems
*mortality
*intestional perforation (3%)
*tissue necrosis
*tissue necrosis
*infection of other organ systems
*mortality
26
What is mortality of Typhoid Fever?
*10%
27
Prevention?
*pasteurization
*proper food handling and preparation
*proper sanitation
*typhoid vaccine
*proper food handling and preparation
*proper sanitation
*typhoid vaccine
28
% of protection provided by Typhoid vaccine?
50-80% protection against S. typhi
29
What are the two prevented typhoid vaccines?
*Oral attenuated vaccine (Ty21a) every 5 yrs
*Injected polysaccharide (Vi) every 2 yrs
*Injected polysaccharide (Vi) every 2 yrs
30
What is treatment for typhoid fever?
*rehydration therapy
*antibiotics (typhoid fever)
*antibiotics (typhoid fever)
31
What antibiotics used for typhoid fever?
*azithromycin
*cephalosporin
*fluroquinolone
*high dose of amoxicillin + probenecid (3 months) for chronic carriers
*cephalosporin
*fluroquinolone
*high dose of amoxicillin + probenecid (3 months) for chronic carriers
Plus de flashcards : Médecine et santé
Muscular SystemMédecine et santé · AnglaisNotDisorders of Primary HemostasisMédecine et santé · AnglaisCHRISTYHTNMédecine et santé · AnglaiscathsimsHemacytometerMédecine et santé · AnglaisJESSQTRANTop 250 Part 1Médecine et santé · Anglaisplane23BPA Practice 2023-24Médecine et santé · AnglaisAl3.2.4 IMMUNITY CELLS AT WORKRKMédecine et santé · AnglaisSabs2023Musculoskeletal Medications: Classes and IndicationsMédecine et santé · AnglaisebradstreetDental Caries (tooth decay)Médecine et santé · AnglaisKatlynKEIntroduction to NeuroanaMédecine et santé · AnglaisAdUvertOther Blood Groups: Lewis SystemMédecine et santé · AnglaisKimHealth Priorities In Australia - CORE 1Médecine et santé · AnglaisAndy
Tous les decks : Médecine et santé
Révise ces decks dans l’app
Gratuit sur iPhone, Android, Mac et le web. Ajoute n’importe quel deck à ton compte en un tap.
