Pseudomonas

Pseudomonas infection- wound infection

Pseudomonas aeruginosa

GNR, Facultative aerobe, flagella motility and pilus attachment, antibiotic resistance, biofilms

Ubiquitous- animals and their enviroments

Compromised tissues

Indirect, direct transmissions; nosocomial infections

Variable (hours to days)

Attachement to and colonization of surfaces using flagella and pilli. Secretion of effector protiens (Virulence factors) disrupts tissues and cells. Exotoxin A inhibits translation, proteases digest tissues and inhibit clot formation, and phospholipase digests cell membrane. The toxin pyocyanine produces a greenish color to site of infection

Skin lesions with green pus, chills, fever, vary based on location (folliculitis, green nail syndrome, keratitis, UTI, pneumonia, etc)

Spread of infection to other organs, bacteremia, sepsis, necrotizing lesions, mortality for bacteremia 12-60%

Antiboitics- multidrug, resistant variants

Disinfection of surfaces and equipment, proper aseptic technique, proper wound care and removal of dead tissue