PART 2 (3A)

“boracic acid”, “sal sedativum”

Toxic when ingested

Absorbed in broken skin

• Buffer in ophthalmic preparation
• Tonicity adjusting agent

E-VALUE of Boric Acid

Antiseptic

Eyewash percent of Boric Acid

Suppository base

Borax

Sodium tetraborate and eyewash

astringent or antiseptic
wash for throat and nose

Component of cold cream

Buffers

Example of Phosphate Buffer System

Has the advantage of containing the dihydrogen and
monohydrogen phosphate ions, one of the
physiological buffer pairs normally found in the body

– insolubility of the phosphate salts of such metals
such as Ag, Zn and Al
– it supports microbial growth

has been used in preparations
containing metals that would otherwise precipitate in
the presence of phosphate

Since BORATES ARE TOXIC, these buffer system
are suitable in

consists of
solution containing boric acid, sodium chloride (to
make it isotonic) and the alkaline solution
containing sodium borate

consists of alkaline solution of sodium carbonate
and acid buffer solution of boric acid and sodium
chloride.

similar to
Feldman’s Buffer System however in place of
NaCl, potassium chloride is used to make it
hypotonic.

Sources of Aluminum

Chief source of Aluminum

the triammonium salt of
aurintricarboxylic acid, is a dye commonly used to
detect the presence of the aluminium ion in an
aqueous solution

Pharmaceutical Uses of Aluminum: