LAB 6 PART 2

-OH is attached to the carbon of the side chain

-OH is attached directly to the benzene ring

Phenol is also known as

• Germicide (protoplasmic poison)

• local anesthetic action but caustic

• Joseph Lister = antiseptic

• 0.1% to 1% conc. – antipruritic in
phenolated calamine lotion

This reaction uses nitrobenzene which is
reduced to aniline, upon addition of HCl it is
converted to aniline hydrochloride and finally
addition of water converts it to phenol,
nitrogen and free HCl

PREPARATION of Phenol

Physical Properties of Phenol is a Colorless crystalline which melts at

Phenol slightly soluble in water at

• Slightly acidic

Phenol Reacts with metallic sodium and potassium to form

Chemical Properties of Phenol reacts with acid chloride and anhydride to form

Chemical Properties of Phenol Reduced by zinc to form

Test for presence of phenol and aromatic amines

Test for presence of phenol

(+) intense red, green, blue, or
PURPLE color

BROMINE WATER TEST RESULT

IODOFORM TEST RESULT

(+) primary or secondary alc – 2-3 secs formation of cloudy
blue green suspension and disappearance of orange
colored reagent

(+) Evidence of reaction (heat, HCl gas) especially
if accompanied by phase separation indicates an
alcohol