BLD 204

B cells recognize a specific antigen with BCR and produce antibodies
can take a while

MHC 1 presents antigen to CD8 T cells that are then activated and stimulate apoptosis

molecules recognized as non self

immunoglobulins that have 2 antigen binding sites and are made of 2 heavy and 2 light chains

undergo phagocytosis

capture and present antigens to T cell
express MHC 2

trap antigens to hold for B cell interaction

recognize antigen in many forms and dont require MHC
produce antibodies

on all nucleated cells
signal to CD8 cells
have a heavy alpha chain and beta-2-microglobulin chain

on all pro APCs
signal to CD4 cells
two peptide chains of more equal size

neutralizes toxins and opsinizes bacteria
can cross placenta
makes up 70-80% of plasma

pentamer
first after immunization
helps with antigen recognition and activation

in mucosa, tears, sweat, bile, breast milk
stops bacteria and viruses from entering epithelium

releases histamine and leukotrienes and recruits eosinophils
fights parasitic infections
involved in hypersensitivity

helps with antigen recognition and activation

bone marrow and thymus

lymph nodes, spleen, and malt

CD8 T cells secrete cytokines that directly kill the infected cells
CD4 cells release cytokines that help stimulate B cells to make antibodies