Immuno Lab Part 1

IgM (large) – able to effect lattice formation without additional enhancement; first antibody produced.
IgG (small) – measures are necessary to see a visible reaction; produced later and more long-lasting.

measures of antibody binding strength, and are important characteristics of the immune response

The strength of a single antibody-antigen interaction. Antibodies with high affinity bind more strongly and stably

The total strength of all interactions between an antibody and an antigen. Avidity is always greater than affinity.

# binding sites, structural arrangements

the test’s ability to correctly identify those with antibodies (true positives); those who have a specific disease or condition! MINIMIZING FALSE NEGATIVES.

1. Venereal disease research laboratory (VDRL)
2. Rapid Plasma Reagin (RPR) Test