Integumentary Cancers + end

Basal Cell Carcinoma

basement membrane

UV exposure

spreads

MOHS surgery

Sqamous cell carcinoma

sqamous cells of the epidermis

UV exposure and genetics

early detection and removal
Moh's procedure
excision
Laser therapy
Photodynamic Therapy
Topical Medications

fair skin
sun sensitive skin
large number, large size, or changing moles

UV exposure

biopsy

removal - excision or MOHS surgery

Genetic, most common in dark skinned individuals
Hariless areas like bottom of feet and nails

Flattening of the dermal-epidermal junction
Changes in basal cells
Decrease # of Langerhans cells
Decrease # of melanocytes
Vitamin D

Decrease dermal thickness
degeneration of elastin and disorganization of collagen
Decrease vascularization

decrease in sweat glands, nerve endings, hair bulb melanocytes, hair follicles

Connective tissue disease that causes fibrosis of skin, joints, blood vessels and internal organs

autoimmune, bacterial, trauma, chemical

diffuse and localized

chronic, progresssive, inflammatory joints

med management, joint replacement, exercise