Cancer Immunotherapy

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1
rituximab target
CD20 cells
2
rituximab drug type
naked MAB
3
alemtuzumab target
CD52
4
alemtuzumab drug type
naked MAB
5
ceruzimab target
EGFR
6
ceruzimab drug type
naked MAB
7
trastuzumab target
HER2/neu protein
8
trastuzumab drug type
naked MAB
9
bevacizumab target
VEGF
10
bevacizumab drug type
naked MAB
11
advantage of MAB joined to chemotherapy
higher tumor selectivity while improving tolerability of the drug
12
advantages of MABs bound to radiotherapy
MAB targets cancer cell, bringing radioactiv risootope to it. The radiation will also kill neighboring cells, which may include cancer cells that don't express the antigen. "Crossfire" effect.
13
blinatumomab is used to treat
lymphocytic leukemia
14
blinatumomab drug type
BiTE antibody
15
B7 1 or 2 binding to t-cells CTLA-4 will
inactivate them
16
blocking the binding of B7 to CTLA-4 will
cause B7 to bind to CD28, allowing the t cells to be active and kill tumor cells.
17
B7 binding to t-cells CD28 will
allow the t cells to be active and kill tumor cells
18
anti CTLA4 antibodies drug type
immune checkpoint inhibitors
19
anti CTLA-4 antibodies MOA
bind to CTLA-4, preventing the binding of B7
20
Blinatumomab drug type
BiTE Antibody
21
Amivantamab-vmjw drug type
BiTE Antibody
22
Tebentafusp-tebn drug type
BiTE Antibody
23
Mosunetuzumab drug type
BiTE Antibody
24
Teclistamab drug type
BiTE Antibody
25
PD-L1 on tumor cells binding to PD-1 on T cells will
stop t cell activation
26
blocking PD-L1 from binding to PD-1 on T cells with an anti PD-L1 or anti PD-1 drug will
allow the t cell to kill the tumor
27
ipilimumab drug type
CTLA-4 inhibitor
28
nivolumab drug type
PD1 and LAG-3 Inhibitor
29
relatlimab drug type
PD1 and LAG-3 Inhibitor
30
pembrolizumab drug type
PD1 inhibitor
31
cemiplimab drug type
PD1 inhibitor
32
avelumab drug type
PD-L1 inhibitor
33
durvalumab drug type
PD-L1 inhibitor
34
atezolizumab drug type
PD-L1 inhibitor
35
drugs that end in leucel drug type
CAR-T
36
drugs that start with a number drug type
Radio
37
drugs that are two words and dont end with leucel drug type
antibody drug conjugate (chemo)
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