PHARMACOLOGY MI

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1
Which is the major cause of MI
Atherosclerosis
2
Which drug is given to reduce blood lipid level
Statins
3
Which drug us given for initial symptomatic treatment
Morphine
Oxygen
Nitroglycerine
Aspirin
Statins
4
Which among the MI drugs reduces the symptoms of anxiety and apprehension
Morphine
5
MOA of Nitroglycerine
Decreases preload
6
Which among these drugs stabilizes thrombus
Statins —>Atorvastatin,Rosuvastatin
7
Which other anti platelet drugs are used along with aspirin
Clopidogrel
Prasugrel
Ticagrelor
Cangrilor
8
Which class of drugs prevent MI
Beta blockers -Atenolol,Metaprolol—Prevent arrhythmis,Infarct expansion
ACe Inhibitors-Ramipril—Prevent infarct expansion
9
Treatment for hypovolemia /Metabolic acidosis
iv fluids +Sodium bicarbonate
10
If patient undergoes cardiac arrest
Treatment?
Asystole —>DC shock cardioversion—Iv epinephrine —Amiodarone
Ventricular fibrillatiom
11
Definitive treatment for MI
Reperfusion therapy
12
Preferred thrombolytics
Streptokinase,Alteplase,Tenecteplase
13
Complication of thrombolytics
Very high risk of bleeding
14
• Which medication reduces blood clotting and is often chewed immediately after a suspected heart attack?
Aspirin
15
• What class of drugs is used to dissolve existing blood clots blocking blood flow to the heart (e.g., tPA)?
Thrombolytics (Clot-busters or Fibrinolytics)
16
• Which medication widens blood vessels to improve blood flow to the heart and is used to treat sudden chest pain?
Nitroglycerin
17
• Which blood-thinning medicine, often given by IV injection, makes the blood less sticky and less likely to form clots?
Heparin
18
• What class of drugs slows the heartbeat, decreases blood pressure, and helps limit heart muscle damage after an MI?
Beta blockers
19
• Which medication is used to relieve chest pain that does not go away after administering nitroglycerin?
Morphine
20
• What class of blood pressure medicines (e.g., ramipril, lisinopril) lowers blood pressure and reduces stress on the heart?
Angiotensin-converting enzyme (ACE) inhibitors
21
• What class of drugs helps lower unhealthy cholesterol levels to prevent clogged arteries?
Statins
22
• Which type of anti-clotting agent is often used alongside aspirin to prevent new clots?
Clopidogrel or other antiplatelet agents
23
What is the drug of choice for immediate pain relief and anxiolytic effect in STEMI patients?
Morphine (Opioid Analgesic)
24
What effect does Morphine have in the management of Myocardial Infarction beyond pain relief?
Reduces preload and pulmonary oedema due to venodilatation, and also reduces afterload.
25
Which drug is administered sublingually and/or intravenously to relieve pain and decrease oxygen demand in MI patients, but should be avoided if SBP is low or the patient is on PDE-5 inhibitors?
Nitroglycerine (NTG)
26
What is the purpose of Fibrinolytic drugs like Streptokinase, Alteplase, and Tenecteplase in acute MI?
To break up (lyse) the blood clot blocking the coronary artery.
27
What class of antiplatelet drug, given alongside Aspirin, is preferred over Clopidogrel in diabetic MI patients according to some recommendations?
Prasugrel (P2Y12 inhibitor)
28
What are the two main classes of anti-ischemic drugs used in the acute management of MI?
Nitrates and Beta Blockers
29
What class of drugs, which includes Atorvastatin and Rosuvastatin, is a key component of long-term MI management to lower cholesterol and stabilize plaque?
Statins (HMG-CoA reductase inhibitors)
30
Which drugs, such as Metoprolol and Atenolol, are given to MI patients to reduce myocardial oxygen consumption by lowering heart rate and blood pressure?
Beta-Adrenergic Blockers
31
What class of drugs, including Captopril and Ramipril, is part of long-term MI management to lower blood pressure and reduce stress on the heart?
Angiotensin-Converting Enzyme (ACE) Inhibitors
32
Which antiplatelet drug is an essential immediate treatment for suspected MI due to its blood clot-reducing property?
Aspirin
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