SHOCK

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Shock syndrome patho
cardiovascular system fails to supply oxygen according to demand due to circulatory compnents leading to hypoperfusion and release of inflammatory mediators
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How do we diagnose Shock
A change in VS, especially a MAP<60 mm Hg accomapnied by evidence of hypoperfusion
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What are s/s of hypoperfusion
decreased urine output, rise in liver enxymes, BUN and Cr, tachypnea, hypoxemia, blood in bodily excretions, hypoglycemia
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Stages of Shock are...
Compensatory, Progressive, Refractory
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Compensatory S/S
increase in heart rate and contractility, vasocontriction
ADH leads to water and sodium retention
gluticosteroids by adrenal cortex cause High BGL
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Progressive S/S
previous stage doesnt meet oxygen demands so...
cells become anaerobic which has a by product of lactic acid
vasodilation, tissue edema
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refractory S/S
MODS (irreversible), death
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Types of Shock
cardiogenic, hypovolemic, obstructive, distributive
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Most common form of shock
hypovolemic
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examples of hypovolemic shock
hemorrhage, dehydration, burns
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treatment of hypovolemic shock
-admin isotonic fluids FIRST such as NS
-admin crystalloid solution, blood, colloid solution
-follow 300 mL of NS for every 100 mL of blood lost
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examples of cardiogenic shock
MI, arrhythmias, valve or septal issue, cardiac surgery
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treatment of cardiogenic shock
Inotropic agents increase contractility
Vasopressors increase BP
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Example of inotropic MED
dobutamine
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example of vasopressor
nitroprusside
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What mechanical devices can increase CO
intra-aortic balloon pump and ventricular assist devices
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how does cardiogenic shock lead to hypoperfusion
contractility decreases so blood remains in chambers, this lowers CO and ejection fraction. BP drops so reflex vasoconstriction kicks in, which decreases perfusion in pulmonary capillaries and lowers ox perfusion
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Examples of obstructive shock
cardiac tamponade, tension pneumo, PE
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treatment of obstructive shock
pericardiocentesis, needle thoracentesis, TpA
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how does obstructive show cause hypperfusion
decreased ventricular filling followed by low CO, low BP
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Examples of distributive shock
neurogenic, anaphylactic, septic
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treatment of anaphylactic shock
EPINEPHRINE
REMOVE ANTIGEN
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epinephrine admin and IR
0.2-0.5 mg IM in thigh q5-15 min anterolateral thigh
IR: bronchodilation, vasoconstriction, contractility
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neurogenic shock patho
imbalanced sympathetic/parsympathetic stimulation leads to vasodilation which decreases CO
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common location of neurogenic shock injury
C3 C4 C5
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treatment of neurogenic shock
traction/surgery to stabilize injury, treat hypoglycemia
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how does septic shock lead to hypoperfusion
microorganism initiate inflammatory response which causes massive vasodilation. lactic acid builds up
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treatment of septic shock
antibiotics, NOREPINEPHRINE
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dx for septic shock
2 blood cultures, urine, sputum, and wound cultures to start antibx within ONE HOUR
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MODS def
is the progressive dysfunction of two or more organ systems as a result of an uncontrolled inflammatory response to severe illness or injury
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most common causes of MODS
sepsis and septic shock
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what interventions decrease oxygen demand
sedation, paralytics, antipyretics, analgesics, cooling measures
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What labs to watch in shock
ABGs, lactic acid, hgb, hct, BUN, Cr, liver enzymes, electrolytes
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