1Neuroscience
Study of the structures and functions of the PNS and CNS
2Mind
Aggregate of mental processes including perception, learning-memory, emotion, consciousness
3Fixed-Action Pattern
Innate coordination of multiple muscle movements that, once triggered by biologically significant stimuli, proceed to completion without requiring further sensory input
4The greylag goose's egg-rolling response is a _____.
Fixed-action pattern
5Instincts
Innate patterns of behavior triggered by environmental stimuli
8Evidence of dualism found in split-brain patients
Split-brain patients performed significantly above chance on tasks that required both of their hemispheres to work together, showing that their brain could still work as a single unified organ even if the two halves couldn't communicate directly with each other.
9Given two equally predictive theories, choose the simpler one.
Principles of parsimony
10The brain and its functions are dynamic (T/F)
T
11What type of memory is dependent on the medial temporal lobe?
Declarative memory
12What brain regions are involved in declarative memories?
Hippocampus (MTL), diencephalon
13Where is nonassociative learning (eg: habituation, sensitization) stored?
Reflex pathways
14Where is basic associative learning stored (both emotional and skeletal muscular responses)?
Amygdala, cerebellum
15Where is memory for priming stored?
Neocortex
16Where is memory for skills/habits stored?
Striatum, motor cortex, cerebellum
17How does habituation occur (synaptically)?
Over time Ca2+ channels will become inactivated, allowing less neurotransmitter release at the synapse and diminishing the next neuron's EPSP. Neurons may also downregulate the number of axon terminals connecting to the postsynaptic neuron.
18Neurons that fire together, wire together
Donald Hebb's hypothesis (1949)
19Desirable characteristics of LTP
Rapid (100 Hz, 1 s tetanization), durable (up to 16 weeks in rabbits), can be strengthened by repetition, supports associative learning (weak inputs can be potentiated if paired with strong ones)
20Black Mirror "Crocodile" summary
Mia Nolan and her husband run over a kid and hide the body, she then murders him when he mentions wanting to turn himself in, murders an investigator who uses a machine to see her memory, then murders her husband all to hide her crime and protect her reputation.
21What effect does electroconvulsive shock have on memory?
Loss of recent memory (not long term)
22Does STM or LTM require protein synthesis?
LTM
23If a group of animals is given protein synthesis inhibitors about 3 hours after learning information, how is their LTM affected?
Not affected
24What effect can injecting RNA from a trained Aplysia into an untrained Aplysia have?
The untrained Aplysia can obtain the trained Aplysia's LTM
25Nicholas Negroponte's prediction (2014)
We will be able to obtain skills/info by swallowing pills and having the info enter our LTM.
26Pavlovian/classical conditioning
S-S learning: 2 stimuli occur close to each other and become functionally linked
27Who discovered classical conditioning using the knee-jerk reflex (before Pavlov)?
Edwin Twitmyer (in 1902)
28Instrumental/operant conditioning
S-R or S-R-O learning: response is associated with an outcome (can include positive/negative reinforcement/punishment)
29Thorndike's law of effect
Behaviors followed by pleasant consequences are more likely to be repeated, behaviors followed by unpleasant consequences are less likely to be repeated.
30Who discovered operant conditioning?
Edward Thorndike
31Edwin R. Guthrie's law of contiguity
A combination of stimuli which has accompanied a movement will, on its recurrence, tend to be followed by that movement.
32When learning, how do longer intertrial intervals affect learning efficiency?
Less trials needed for learning
33Contiguity theory
A close temporal relationship between stimuli, or between stimulus and response, is necessary for an association to form.
34If the CS and US occur apart, the CS will predict the absence of the US.
Inhibitory conditioning
35If the CS and US occur together, the CS will predict the presence of the US.
Excitatory conditioning
36Brain region involved in salivary conditioning
Auditory, insular (gustatory) and orbitofrontal cortices
37Brain regions involved in eyeblink conditioning
Cerebellum
38Brain regions involved in fear conditioning (footshock)
Amygdala
39Brain regions involved in taste aversion conditioning (gastric sickness)
Insular and orbitofrontal cortices, amygdala
40What is extinction of associative learning?
New learning that the CS no longer predicts the US, spontaneous recovery of the association is possible in the future.
41Stimulus generalization
Learning spreads to similar stimuli
42Stimulus discrimination
Learning to discriminate between similar stimuli
43Experimental neurosis
Breakdown caused when the difference between similar stimuli is too small to detect
44Second-order conditioning
A cue that predicts the CS will also gain meaning, even if the CS isn't followed by the US. The response to the cue predicting the CS will be weaker than the response to the CS.
45Overshadowing
When two cues predict the US together, the stronger cue will become the stronger CS, and the weaker cue will be overshadowed.
46Contingency
Conditioning requires an information/predictive relationship between the CS and US.
47How to calculate contingency
P(US | CS) - P(US | no CS)
48Biological predisposition
Evolution constrains which associations are easy to learn
49What is different about taste aversion conditioning compared to other forms of conditioning?
Takes only 1 trial to form association, works when taste and illness happen hours apart, works even if animals are unconscious when sickness is induced.
50Unforgettable (1996) summary
Medical examiner David Crane steals a neurobiologist's memory-transferring serum so he can learn about his wife's murder and catch the killer.
51CR is a (partial) replica of UR
Stimulus substitution
52CR is not UR
Anticipatory response
53CR is opposite to UR
Compensatory response
54Emotion working definition
Brain state that evolved to guide behaviors that promote survival and reproduction.
55Feeling
Conscious labeling of emotion
56James-Lange peripheral theory of emotion
We feel emotion because our body reacts.
57Cannon-Bard central theory of emotion
Emotion and bodily response happen at the same time, independently.
58Schachter-Singer two-factor theory of emotion
Emotion = bodily arousal + cognitive label from context.
59The first anatomical model linking learning, memory, and bodily responses. Does not include the amygdala.
Papez circuit (1937)
60Top level control center of autonomic or endocrine systems, controls the 4 fs (fight, flight, feed, fuck).
Hypothalamus
61Kluver-Bucy Syndrome
Animals without a medial temporal lobe (contains amygdala) showed no fear.
62Urbach-Wiethe Disease
Rare genetic disorder that causes bilateral destruction of the amygdala (its tissue is replaced with calcium mineral deposits).
63Little Albert Experiment (Watson and Rayner, 1920)
Little Albert was a kid taught to fear white rats through classical conditioning.
64Cortical route of auditory fear conditioning
Signal travels from the thalamus to the auditory cortex to the amygdala
65Subcortical route of auditory fear conditioning
Signal travels from the thalamus to the amygdala
66Why might therapy be ineffective for conditioned fears?
It doesn't address subconscious fears
67Memory reconsolidation
Stored memories can be activated, modified, and reconsolidated.
68How did the drug Muscimol affect the rats in the approach food-avoid predator experiments?
It inhibited their amygdala, allowing them to get pellets that were further from their nest.
69How did the drug Bicuculine affect the rats in the approach food-avoid predator experiments?
It increased amygdala activation and fear, so that rats were less willing to get pellets further from their nest.
70How did amygdala lesions affect the rats in the approach food-avoid predator experiments?
It allowed them to get pellets that were further from their nest.
71What did rats find innately scary about the robots in the approach food-avoid predator experiments?
Large robots, robots moving toward rats, especially at high velocity were scary. (Stationary robots weren't scary, neither were robots not moving toward the rat)
72What two brain regions elicit fear when stimulated?
Amygdala, dorsal PAG
73Stimulating the amygdala of an animal with a PAG lesion will cause fleeing, but stimulating the PAG of an animal with an inactivated amygdala will not. (T/F)
T
74Do dPAG neurons respond to external threat?
Yes
75How does optogenetics work?
A gene is delivered into neurons instructing them to make light-sensitive 'opsin' proteins, which embed themselves into the neurons' membranes. Scientists can then shine different colored lights on the neurons through an implanted optical fiber to turn them on or off.
76Aggression
Behavior that threatens/harms member of the same species.
77Resident-Intruder Paradigm
Another male rat is introduced into a male rat's home cage, the two are scared of each other and fight.
78Shock-elicited aggression paradigm
Two rats are shocked together, they blame each other and attack each other.