NS201 Midterm

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1
How do antibiotic resistant bacteria show evolution in action?
The weak bacteria get killed by the antibiotics very effectively, but a few gain immunity. Since bacteria multiply so fast, we can see the evolution of a bacterial strain unfold in weeks, months, or years.
2
The weak bacteria get killed by the antibiotics very effectively, but a few gain immunity. Since bacteria multiply so fast, we can see the evolution of a bacterial strain unfold in weeks, months, or years.
How do antibiotic resistant bacteria show evolution in action?
3
Who observed DNA and chromosomes for the first time?
Frederick Miescher isolated DNA from cells
Walther Flemming observed "thread like strings" (chromosomes) during cell division
4
Frederick Miescher isolated DNA from cells
Walther Flemming observed "thread like strings" (chromosomes) during cell division
Who observed DNA and chromosomes for the first time?
5
Haploid
an organism or cell having only one complete set of chromosomes (gamete)
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an organism or cell having only one complete set of chromosomes (gamete)
Haploid
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Diploid
an organism or cell having two complete sets of chromosomes or twice the haploid number (fertilized egg)
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an organism or cell having two complete sets of chromosomes or twice the haploid number (fertilized egg)
Diploid
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homologous chromosomes
Chromosomes that have the same sequence of genes and the same structure
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Chromosomes that have the same sequence of genes and the same structure
homologous chromosomes
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Allele
one of a number of different forms of a gene
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one of a number of different forms of a gene
Allele
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Who calculated the age of the Earth?
James Ussher, October 26th 4000 BCE at 9 am
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James Ussher, October 26th 4000 BCE at 9 am
Who calculated the age of the Earth?
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Catastrophism
Georges Cuvier: Fixity in species, geological features caused by events, extinction explains disappearance in fossil record
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Georges Cuvier: Fixity in species, geological features caused by events, extinction explains disappearance in fossil record
Catastrophism
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Gradualism
James Hutton: geological features caused by gradual mechanisms (erosion, glaciers, etc)
Charles Lyell: same geological processes are still happening
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James Hutton: geological features caused by gradual mechanisms (erosion, glaciers, etc)
Charles Lyell: same geological processes are still happening
Gradualism
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What does natural selection depend on?
variation among individuals in a population, variation must be genetic, sources of genetic diversity are mutations and sexual reproduction
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Divergent Evolution
two species evolve in different directions from a common ancestor. Homologous structures, i.e. horse legs and human arms (all mammals have the same arm bone structure)
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two species evolve in different directions from a common ancestor. Homologous structures, i.e. horse legs and human arms (all mammals have the same arm bone structure)
Divergent Evolution
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Convergent Evolution
similar structures arise independently in unrelated species. Analogous structures i.e. bird wings and insect wings
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similar structures arise independently in unrelated species. Analogous structures i.e. bird wings and insect wings
Convergent Evolution
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Artificial Selection
selective breeding of plants and animals to increase desired characteristics
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selective breeding of plants and animals to increase desired characteristics
Artificial Selection
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How do antibiotic resistant bacteria show evolution in action?
The weak bacteria get killed by the antibiotics very effectively, but a few gain immunity. Since bacteria multiply so fast, we can see the evolution of a bacterial strain unfold in weeks, months, or years.
27
The weak bacteria get killed by the antibiotics very effectively, but a few gain immunity. Since bacteria multiply so fast, we can see the evolution of a bacterial strain unfold in weeks, months, or years.
How do antibiotic resistant bacteria show evolution in action?
28
Vestigial Structures
A structure that is present in an organism that was once useful to an ancestor, but is not longer useful--appendix, tailbone
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A structure that is present in an organism that was once useful to an ancestor, but is not longer useful--appendix, tailbone
Vestigial Structures
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Cell Theory
idea that all living things are composed of cells, cells are the basic units of structure and function in living things, and new cells are produced from existing cells
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idea that all living things are composed of cells, cells are the basic units of structure and function in living things, and new cells are produced from existing cells
Cell Theory
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Mendel's 3 Laws of Hereditary
Law of Dominance: traits can be dominant or recessive
Law of Segregation: alleles separate during gamete formation and join during fertilization
Independent Assortment: the allele a gamete receives for one gene does not influence the allele received for another gene
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Law of Dominance: traits can be dominant or recessive
Law of Segregation: alleles separate during gamete formation and join during fertilization
Independent Assortment: the allele a gamete receives for one gene does not influence the allele received for another gene
Mendel's 3 Laws of Hereditary
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Who proposed the "chromosome theory of heredity", and how did it relate to Mendel's
work?
Walter Sutton and Theodor Boveri
Chromosomes behave like Mendel's "factors"
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Walter Sutton and Theodor Boveri
Chromosomes behave like Mendel's "factors"
Who proposed the "chromosome theory of heredity", and how did it relate to Mendel's
work?
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Ploidy
number of sets of chromosomes in a cell
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Chromosomes that have the same sequence of genes and the same structure
homologous chromosomes
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homologous chromosomes
Chromosomes that have the same sequence of genes and the same structure
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number of sets of chromosomes in a cell
Ploidy
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Gene
A segment of DNA on a chromosome that codes for a specific trait
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A segment of DNA on a chromosome that codes for a specific trait
Gene
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Who observed DNA and chromosomes for the first time?
Frederick Miescher isolated DNA from cells
Walther Flemming observed "thread like strings" (chromosomes) during cell division
43
Frederick Miescher isolated DNA from cells
Walther Flemming observed "thread like strings" (chromosomes) during cell division
Who observed DNA and chromosomes for the first time?
44
Homozygous
An organism that has two identical alleles for a trait
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An organism that has two identical alleles for a trait
Homozygous
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Heterozygous
An organism that has two different alleles for a trait
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An organism that has two different alleles for a trait
Heterozygous
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hemizygous

A gene present on the X chromosome that is expressed in males in both the recessive and dominant condition
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A gene present on the X chromosome that is expressed in males in both the recessive and dominant condition
hemizygous
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dominant

a trait expressed in homozygous and heterozygous
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a trait expressed in homozygous and heterozygous
dominant
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recessive

a trait expressed only in homozygous
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a trait expressed only in homozygous
recessive
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Genotype vs. Phenotype

-Genotype : Collection of alleles
-Phenotype : Physical expression of alleles
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-Genotype : Collection of alleles
-Phenotype : Physical expression of alleles
Genotype vs. Phenotype
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Incomplete Dominance

An organism inherits and expresses both recessive and dominant traits: a pink flower inherited both red and white colors
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An organism inherits and expresses both recessive and dominant traits: a pink flower inherited both red and white colors
Incomplete Dominance
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Codominance
Two dominant traits can be expressed: AB blood type; both the dominant A and dominant B types are expressed
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Two dominant traits can be expressed: AB blood type; both the dominant A and dominant B types are expressed
Codominance
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Multiple Alleles

A trait is phenotypically expressed in an organism that was not phenotypically expressed in either parent: Parent 1 has type A blood, Parent 2 has type B, and offspring has type O
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A trait is phenotypically expressed in an organism that was not phenotypically expressed in either parent: Parent 1 has type A blood, Parent 2 has type B, and offspring has type O
Multiple Alleles
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Gene linkage

Certain genes are only on linked to either X or Y, X recessive is the most common
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Certain genes are only on linked to either X or Y, X recessive is the most common
Gene linkage
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Epistasis

One gene masks another gene, like black labs
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One gene masks another gene, like black labs
Epistasis
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Know the blood groups in humans (alleles, genotypes and phenotypes)

Type A: i^A i^A or i^A i^i
Type B: i^B i^B or i^B i^i
Type AB: i^A i^B
Type O: i^i i^i
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Type A: i^A i^A or i^A i^i
Type B: i^B i^B or i^B i^i
Type AB: i^A i^B
Type O: i^i i^i
Know the blood groups in humans (alleles, genotypes and phenotypes)
68
What is polygenic inheritance?

When other factors besides genotype influences phenotype: Height, there is no short and tall, there is a spectrum. Diet and environment of the parent pre-birth and offspring influence the height of the offspring
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When other factors besides genotype influences phenotype: Height, there is no short and tall, there is a spectrum. Diet and environment of the parent pre-birth and offspring influence the height of the offspring
What is polygenic inheritance?
70
Microevolution

Change in allele frequencies in a population over generations.
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Change in allele frequencies in a population over generations.
Microevolution
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Macroevolution

large-scale evolutionary changes that take place over long periods of time
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large-scale evolutionary changes that take place over long periods of time
Macroevolution
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gene pool

Combined genetic information of all the members of a particular population
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Combined genetic information of all the members of a particular population
gene pool
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allele frequency
how often an allele appears in a population
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how often an allele appears in a population
allele frequency
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genotype frequency
how often a genotype (set of alleles) appears in a population
79
how often a genotype (set of alleles) appears in a population
genotype frequency
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Heterozygote advantage
Greater reproductive success of heterozygous individuals compared to homozygotes; tends to preserve variation in gene pools. (Sickle cell recessive prevents malaria)
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Greater reproductive success of heterozygous individuals compared to homozygotes; tends to preserve variation in gene pools. (Sickle cell recessive prevents malaria)
Heterozygote advantage
82
Why is Hardy-Weinberg equilibrium not seen in natural, wild populations?

H-W requires perfect conditions, which can never occur in a natural population due to 5 factors
83

H-W requires perfect conditions, which can never occur in a natural population due to 5 factors
Why is Hardy-Weinberg equilibrium not seen in natural, wild populations?
84
Factors that lead to changes in allele frequency in populations
Mutations, genetic drift: founder effect and bottleneck, gene flow: immigration and emigration, natural selection, sexual selection (non-random mating, more attractive mate more)
85
Mutations, genetic drift: founder effect and bottleneck, gene flow: immigration and emigration, natural selection, sexual selection (non-random mating, more attractive mate more)
Factors that lead to changes in allele frequency in populations
86
Stabilizing selection
In a bell curve, the very middle is selected for: baby weight
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In a bell curve, the very middle is selected for: baby weight
Stabilizing selection
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Directional selection
In a bell curve, one end of the spectrum is selected for: One color of moth is more fit for a particular environment, while the other is very unfit
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In a bell curve, one end of the spectrum is selected for: One color of moth is more fit for a particular environment, while the other is very unfit
Directional selection
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Disruptive selection
Both extremes are selected for, while the middle is most unfit: Finches with very small and very large beaks are fit for the Galapagos Islands, while finches with a medium size beak are unable to access either food source.
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Both extremes are selected for, while the middle is most unfit: Finches with very small and very large beaks are fit for the Galapagos Islands, while finches with a medium size beak are unable to access either food source.
Disruptive selection
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