Exam 1

46 flashcardsby Kaylie
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1
Gross Anatomy
Can be seen with the naked eye only
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Comparative Anatomy
Animal Model
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Histology
Using the microscope
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4 Classifications of tissue
a.) Epithelial b.) Muscle: Skeletal, Cardiac, Smooth c.) Nerve d.) Connective tissue: RBC's, WBC's, Bone, Tendons, etc
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Embryonic stem cells
1.) Ectoderm, mesoderm, and endoderm
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Skeletal
Highest amount of force
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Cardiac
No fatigue
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Smooth
Lowest amount of fatigue
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Etiology
The cause of the disease
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Pathogenesis
The beginning or expression of the disease
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Morphological Changes
Physical changes to cells and tissues
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Functional Changes
"No Workee"
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4 Categories of Disease
1.) Abnormalities to the Cell Membrane 2.) Reduction in O2 delivery to cells (decreade in aerobic respiration 3.) Abnornalities to enzymes - An enzyne speeds up biochemical reactions 4.) Genetic Infidelity
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Genetic Central Dogma
Dna - Dna (Replication) DNA - RNA (Transcription) RNA - Amino acids-> Protiens (Translation)
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Physiological Systems
1.) Skeleton 2.) Cardiovascular 3.) Repiratory 4.) Digestion 5.) Urinary 6.) Brain or central nervous system 7.) Skeletal Muscle 8.) Skin 9.) Immune system 10.) Reproduction 11.) Endocrine System
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6 Macromolecules of Human life
1.) Carbohydrates (CHO) 2.) Lipids (Fats) 3.) Protiens - make all other structures 4.) Minerals - cofactors 5.) Vitamins - cofactors, water + fat soluble 6.) Water - faciliate all Biochem. reactions
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3 Characterisics of Living Things in
1.) Structurally Complex
2.) Extract, Transform (Convert), and use Energy
3.) Ability to Replicate
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Homeostatisn
The internal and external environment of the cell must by maintained in a stable, unchanging, constant condition
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1838 Schleiden and Schwann "Cell Doctrine Theory"
1.) Cell is basic unit of life
2.) Cells -> Tissues -> Organs -> Systems -> Organism
3.) All cells arise from pre-existing cells (cell replication)
4.) All 11 physiological systems are designed to facilitate the cell needs
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1872 Claude Bernard
The interior of the cell is fixed and stable
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1929 Walter Cannon
1. Coined Term Homeostasis
a. 02
b. pH
c. temp
d. etc…
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Principles of Homeostatis
i. Traditional 5 component homeostatic pathway template
1. Parameter: The item that is homeostatically regulated
a. Normal Range: Gender, Lifestyle
b. Below Normal: Hypo Condition
c. Above Normal: Hyper Condition
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Sensing Structures
a. Cell populations: small
b. Glands: medium
c. Organs: large
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Signals
The unique communication between the sensing structures + the structures responsible for returning or correcting the parameters back to normal. Chemical: slower, Electrical: instantaneous
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Positive Feedback System (loop)
Temporary amplification of the signal and its effects before returning the parameters back to normal. Fetal development and Lactation
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Negative Feedback System (loop)
NO amplification but without delay returns the parameters back to normal. Ca2+, Glucose, and water
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Parameter: Fetal Development
1.) Normal Range: 38-42 weeks 2.) Before 38 weeks - Premature 3.) After 42 weeks - Overdue
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Correction
Glycogen tells the liver to convert Glycogen into glucose and send it to the brain
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Consequences
Lowered cognition, mood change (aggression being most common)
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Hypoglycemia
Brain
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Hyperglycemia
Small intestine
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Hypoglycemia Consequences
Brain is starved for food
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Hyperglycemia Consequences
Type I and type II diabetes
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Proton
Positive
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Neutron
Neutral
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Electron
Negative
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Opposite charges...
Attract
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Neutral charges...
Bind to neutral charges
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Electron orbital Rules
a.) 1st orbital shell - 2 electrons max b.) 2nd orbital shell - 8 electrons max c.) 3rd orbital shell - 8 electrons max
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Elements of Life
H,O & S, N, C, PO43-, Na+, K+, Ca2+, CI-
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Hydrogen (Neutral)
a.) Missing 1 electron - can make 1 single bond, H- b.) Building Form
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Proton
a.) Positive charge b.) Involved in pH scale as an acid
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Hydroxy (1) ion
a.) Negative b.) Involved in the pH scale as a base or alkaline c.) Most common form is HCO3- (Bicarbonate)
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pH
The quantity (product) of H+ & HCO3- dissolved in the water portion of plasma
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Human Blood pH scales
a.) Norm: 7.35-7.45 b.) Acidic: 6.90 c.) Basic: 7.70
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Buffering Equation
Acid + Base = Neutral
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