1Gross Anatomy
Can be seen with the naked eye only
2Comparative Anatomy
Animal Model
3Histology
Using the microscope
44 Classifications of tissue
a.) Epithelial b.) Muscle: Skeletal, Cardiac, Smooth c.) Nerve d.) Connective tissue: RBC's, WBC's, Bone, Tendons, etc
5Embryonic stem cells
1.) Ectoderm, mesoderm, and endoderm
6Skeletal
Highest amount of force
8Smooth
Lowest amount of fatigue
9Etiology
The cause of the disease
10Pathogenesis
The beginning or expression of the disease
11Morphological Changes
Physical changes to cells and tissues
12Functional Changes
"No Workee"
134 Categories of Disease
1.) Abnormalities to the Cell Membrane 2.) Reduction in O2 delivery to cells (decreade in aerobic respiration 3.) Abnornalities to enzymes - An enzyne speeds up biochemical reactions 4.) Genetic Infidelity
14Genetic Central Dogma
Dna - Dna (Replication) DNA - RNA (Transcription) RNA - Amino acids-> Protiens (Translation)
15Physiological Systems
1.) Skeleton 2.) Cardiovascular 3.) Repiratory 4.) Digestion 5.) Urinary 6.) Brain or central nervous system 7.) Skeletal Muscle 8.) Skin 9.) Immune system 10.) Reproduction 11.) Endocrine System
166 Macromolecules of Human life
1.) Carbohydrates (CHO) 2.) Lipids (Fats) 3.) Protiens - make all other structures 4.) Minerals - cofactors 5.) Vitamins - cofactors, water + fat soluble 6.) Water - faciliate all Biochem. reactions
173 Characterisics of Living Things in
1.) Structurally Complex
2.) Extract, Transform (Convert), and use Energy
3.) Ability to Replicate
18Homeostatisn
The internal and external environment of the cell must by maintained in a stable, unchanging, constant condition
191838 Schleiden and Schwann "Cell Doctrine Theory"
1.) Cell is basic unit of life
2.) Cells -> Tissues -> Organs -> Systems -> Organism
3.) All cells arise from pre-existing cells (cell replication)
4.) All 11 physiological systems are designed to facilitate the cell needs
201872 Claude Bernard
The interior of the cell is fixed and stable
211929 Walter Cannon
1. Coined Term Homeostasis
a. 02
b. pH
c. temp
d. etc…
22Principles of Homeostatis
i. Traditional 5 component homeostatic pathway template
1. Parameter: The item that is homeostatically regulated
a. Normal Range: Gender, Lifestyle
b. Below Normal: Hypo Condition
c. Above Normal: Hyper Condition
23Sensing Structures
a. Cell populations: small
b. Glands: medium
c. Organs: large
24Signals
The unique communication between the sensing structures + the structures responsible for returning or correcting the parameters back to normal. Chemical: slower, Electrical: instantaneous
25Positive Feedback System (loop)
Temporary amplification of the signal and its effects before returning the parameters back to normal. Fetal development and Lactation
26Negative Feedback System (loop)
NO amplification but without delay returns the parameters back to normal. Ca2+, Glucose, and water
27Parameter: Fetal Development
1.) Normal Range: 38-42 weeks 2.) Before 38 weeks - Premature 3.) After 42 weeks - Overdue
28Correction
Glycogen tells the liver to convert Glycogen into glucose and send it to the brain
29Consequences
Lowered cognition, mood change (aggression being most common)
31Hyperglycemia
Small intestine
32Hypoglycemia Consequences
Brain is starved for food
33Hyperglycemia Consequences
Type I and type II diabetes
37Opposite charges...
Attract
38Neutral charges...
Bind to neutral charges
39Electron orbital Rules
a.) 1st orbital shell - 2 electrons max b.) 2nd orbital shell - 8 electrons max c.) 3rd orbital shell - 8 electrons max
40Elements of Life
H,O & S, N, C, PO43-, Na+, K+, Ca2+, CI-
41Hydrogen (Neutral)
a.) Missing 1 electron - can make 1 single bond, H- b.) Building Form
42Proton
a.) Positive charge b.) Involved in pH scale as an acid
43Hydroxy (1) ion
a.) Negative b.) Involved in the pH scale as a base or alkaline c.) Most common form is HCO3- (Bicarbonate)
44pH
The quantity (product) of H+ & HCO3- dissolved in the water portion of plasma
45Human Blood pH scales
a.) Norm: 7.35-7.45 b.) Acidic: 6.90 c.) Basic: 7.70
46Buffering Equation
Acid + Base = Neutral