1Basic structional and functional unit
Cell
2smallest living parts of the body
cell
3Two type of cell
Eukaryotic and Prokaryotic
4Cells without a Nucleus
Prokaryotic Cell
5Cells that contains Nucleus
Eukaryotic Cell
6Are usually larger than prokaryotic cells, and they
are found mainly in multicellular organisms.
Eukaryotic Cell
7When the molecules themselves combine
together in many different ways they form
the basic unit of any living organism.
Cell Biology
8All living organisms contain a multitude
of cell types, whose main functions are to maintain a proper ___ in the body, which is maintaining the internal environment of the body in a relatively constant state.
Homeostasis
9The cell is composed of two basic parts
•Cytoplasm/Nucleus
•Plasma Membrane
10forms a selective, structural barrier or boundary between the internal and the external environments
cell or a plasma membrane (plasmalemma)
11The membrane that surrounds the cell consists
of
Phospholipid bilayer
12Interspersed within and embedded in the
phospholipid bilayer of the cell membrane are
the;
-integral membrane proteins
-peripheral membrane proteins
-cholesterol
13Located on the external surface of the
cell membrane is a delicate, fuzzy cell
coat called the arranged on both
the inner and outer surfaces of the cell
membrane.
glycocalyx
14It is present on all cells, but it is especially conspicuous on the coherent layer of cells that
form the epithelium lining the gastrointestinal tract.
glycocalyx
15The lipid bilayer of the cell membrane has
a fluid consistency, and, as a result, the
compositional structure of the cell
membrane is characterized as a
fluid mosaic model
16thier ___ arranged on both the inner and outer surfaces of the cell membrane.
Polar Heads
17The ___ of the lipid layers face each other in the center of the membrane.Used for cell-to-cell
communication
non polar tails
18forms an important barrier between the internal and external environments of the cell, which then
maintains a constant intracellular environment
Selective Permeability
19Two types of proteins in membrane transport
Ion - Channels
Carrier -
Proteins
20Posses an aqueous pore and may be gated (require the presence of a stimulus or signaling molecules)
or ungated (always open).
Ion channels Proteins
21Used for cell-to-cell
communication
Signaling Molecules
22Diffuse through the cell membrane to activate intracellular messenger systems by binding to receptor molecules located in either the cytoplasm or the nucleus.no
energy required (via ion
channel or carrier proteins)
Hydrophobic or Lipid-soluble signaling molecules
23Initiate a specific sequence of responses by binding to receptors embedded in the cell
membrane
Hydrophilic Signaling Molecules
24Can permit the passage of
molecules with or without
the expenditure of energy.
Can utilize ATP-driven methods.
Carier Proteins
25Membrane Transport System that down an ionic or concentration gradient
Passive (simple diffusion)
26Membrane Transport System that is no energy required (via ion channel or carrier proteins)performs the
uptake and transfer of molecules and solids
across the cell membrane into the cell
interior.
Facilitated Diffusion
27Membrane Transport System tha is energy required, usually against a gradient (only via carrier proteins)
Active
28Other substances, such as glucose, ions, or proteins, cannot pass through the cell membrane
and cross it only by specific
Transport Mechanisms
29performs the uptake and transfer of molecules and solids across the cell membrane into the cell
interior.its
endocytosis
30 the release of material from the cell cytoplasm across the cell membrane is called
Exocytosis
313 types of
endocytosis
Pinocytosis, Plagocytosis , Receptor mediated endocytosis
32it's a type of endocytosis that process by which cells ingest small molecules of extracellular fluids
or liquids. (nonspecific uptake of molecules in
an aqueous solution)
Pinocytosis
33it's a type of endocytosis that refers to the ingestion or intake of large particles by the cells, such as bacteria, worn out cells, or cellular debris.
Plagocytosis
34it's a type of endocytosis is specific uptake of substances, such as low-density lipoproteins.
Receptors-mediated endocytosis
35is used for products that are released from cells continuously, as soon as synthesis is complete,
such as procollagen for the ECM.
Constitutive secretion
36occurs in response to signals coming to the cells, such as the release of digestive enzymes from
pancreatic cells in response to specific stimuli.
Regulatedsecretion
37consists largely of a fluid component – cytosol
Cytoplasm
38It bathes metabolically the active structures called
organelle
39Contains hundreds of enzymes that produce
building blocks for larger molecules and break
down small molecules to liberate energy.
cytosol
40performs a specialized metabolic function that is essential for maintaining cellular homeostasis
and cell life.
Organelles
41is the largest organelle of a cell.
nucleus
42The nucleus consists of
chromatin, one or more nucleoli (singular, nucleolus), and nuclear matrix.
43The nucleus contains the cellular genetic material ___, which encodes all cell structures
and functions.
deoxyribonucleic acid (DNA)
44Composed of an Inner and Outer membrane with an intervening Perinuclear Cistern.
Nuclear envelope
45 At intervals around the periphery of the nucleus, the outer and inner membranes of the nuclear envelope fuse to form numerous
Nuclear Envelope
46are membrane-enclosed organelles with arrays of enzymes specialized for aerobic respiration and production of adenosine triphosphate (ATP), with high-energy phosphate bonds, which supplies energy for most cellular activities.
Mitochondria
47The inner membrane exhibits numerous folds called
cristae
48extends from the surface of the nucleus to the cell membrane
• may be rough or smooth are small, electron-dense
granules found in the
cytoplasm of the cell
Endoplasmic reticulum
49 is an extensive network of sacs, vesicles, and interconnected flat tubules called
cristernae
50is characterized by numerous flattened, interconnected cisternae, whose cytoplasmic surfaces are covered or studded with granules
called
Ribosomes
51• is devoid of ribosomes, and it consists primarily of anastomosing or connecting tubules.
Smooth Endoplasmic reticulum
52 are small, electron-dense granules found in the
cytoplasm of the cell
Ribosomes
53 are organelles produced by the Golgi apparatus that are highly variable in appearance and size.
Lysosomes
54•completes posttranslational
modifications of proteins synthesized in
the RER and then packages and
addresses these proteins to proper
destinations.
• composed of smooth membranous
saccules containing enzymesEpithelial cells contain the intermediate
filaments
Golgi Apparatus or Golgi Complex
552 distinct sides of golgi apparatus
cis face and trans face
56 • consists of a network of tiny protein filaments and tubules that extend throughout the cytoplasm.
• It serves the cell’s structural framework.
Cytoskeleton
57 Three types of filamentous proteins:
-Microfilaments
– intermediate filaments, and
– microtubules
58Epithelial cells contain the intermediate filaments
keratin
59filaments are found in many mesenchymal cells.
Vimentin
60filaments are found in both smooth and striated muscles.
desmin
61proteins are found in the nerve cells and their processes.
neuro filament
62are found in astrocytic glial cells of the nervous system.
glial filaments
63intermediate filaments are found on the inner layer of the nuclear membrane.
lamin
64• are found in almost all cell types except red
blood cells.
• They are the largest elements of the
cytoskeleton. centrioles
Microtubules
65All microtubules originate from the microtubule-organizing center, the____in the cytoplasm, which contains a pair of ___.
Centrosome , centrioles
66is an area of the cytoplasm located
near the nucleus.
Centrosome
67Within the centrosome are two small cylindrical structures
Centrioles
68 are temporary structures that accumulate in the cytoplasm of certain cells.
cytoplasmic inclusions