Gastroeneterology

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1
Gastrointestinal track steps
mouth - mastication
tongue pushes food down the throat
epiglottis prevents choking
esophagus - peristalsis pushes food to the stomach
stomach - food is mixed up and becomes chyme
chyme - stomach content that enters the small intestine
small intestine - juices from p ancreas, liver, and intestine are mixed with chyme. water is removed and nutrients
enter the blood stream
large intestine - absorbs water, waste, becomes solid
rectum - stool leaves the body
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What is GERD?
liquids reflux to esophagus
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Symptoms of GERD
chest pyrosis, acid reflux, food regurgitation, dysphagia, dry cough, globus sensation, laryngitis
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Diagnosis of GERD
EGD - may see esophagitis, gastritis, barrett's esophagitis, strictures, cancer, H pylori
or based on medical hx
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Management of GERD
PPIs - Omeprazole (Prilosec), Esomeprazole (Nexium)
H2 blockers - Famotidine (Pepcid)
Lifestyle modifications, weight loss, smoking cessation, diet changes
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What is functional dyspepsia?
indigestion without an obvious cause
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symptoms of functional dyspepsia
epigastric abd pain, bloating, n/v, belching, early satiety
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diagnosis of functional dyspepsia
based on symptoms
EGD - unremarkable
24 impedance study - measures how often acid enters the stomach and how long it stays
usually no abnormal reflux
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treatment of functional dyspepsia
H2 blockers, PPI, Carafate, Anti spasmodics, TCA
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what is crohn's disease
inflammation in the GI tract from mouth to anus
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crohn's affects the ______ layers of the intestinal walls
deeper
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crohn's most often occurs in the _________ ________ ________ and ______
distal small intestine (ileum), colon
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crohn's most common age
late teens-20s and 50s-70s
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symptos of crohn's
abd pain, diarrhea, stenosis from scar tissue, IDA, weight loss, fever, joint pain, skin rashes, perianal disease (abcess/fistula)
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diagnosis of crohns
colonscopy, stool calprotectin, labs - ESR, CRP, Irons studies
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Risks of crohn's
colon cancer, obstruction, surgery, hospitalization
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management of crohn's
rarely 5-ASA, biologics, prednisone
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what is ulcerative colitis
chronic inflammation of colon and rectum
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symptoms of ulcerative colitis
ulcerations in the colon, bloody stool, diarrhea, abd pain, rectal pain, fever, weight loss, fatigue, anorexia, nocturnal BMs, urgency
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diagnosis of ulcerative colitis
coloscopy
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management of ulcerative colitis
surgery, 5-ASA, immunomodulators, biologics
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risks of ulcerative colitis
colon cancer, emergency surgery, hospitalization
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ulcerative colitis rarely causes _________ ___________
extraintestinal manifestations
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what is IBS
non inflammatory disorder that affects large intestine
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criteria for IBS
abd pain at least 1x per week for 3 months
associated with change in stool, frequency, consistency
changes in defacation
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overlapping disorders with IBS
SIBD - small intestinal bacterial overgrowth
lactose intolerance
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symptoms of IBS
abd pain, diarrhea, constipation or both
abd pain improves after BM, abd bloating
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diagnosis of IBS
based on history, if red flags then colonoscopy
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management of IBS
probiotics, anti-spasmodics, TCA, peppermint oil, laxatives, anti diarrheals, FODMAP diet
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risks of IBS
no risk of colon cancer!
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what is Helicobacter Pylori
bacteria that lives in the stomach, typically does not cause illness
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H pylori is a major risk factor for
peptic ulcer disease
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H pylori is responsible for majority ulcers in the _________ and __________
stomach and duodenum
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H pylori is spread through _____ and ______ contamination in childhood
food and water
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symptoms of H pylori
epigastric abd pain, anorexia, bloating, n/v
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diagnosis of H pylori
breath or stool test
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management of H pylori
antibiotics
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what is constipation
less than 3 BMs per week
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causes of constipation
pelvic floor dysfunction, hormones, IBS, diet, IBD, Inadequate fluids
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diagnosis of constipation
HPI, anorectal manometry, colonoscopy
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management of constipation
fiber, fluids, laxatives, Rx therapies
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what is diarrhea
watery stool that lasts beyond a week or longer
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causes of diarrhea
infection, IBS, IBD, medication, diet, surgery, lactose intoleance
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diagnosis of diarrhea
stool studies, colonoscopy, imaging
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management of diarrhea
fiber, antibiotics, FODMAP diet
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what is colorectal cancer
cells in the colon or rectum grow out of control
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pylops
abnormal growths that during screen and removed, can grow into cancers if not removed
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risk factors for colorectal cancer
IBD, fam hx, genetic diseases (Lynch syndrome, familial adenomatous polyposis)
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risk reducers of colorectal cancer
tobacco, physical activity, healthy diet, limiting alcohol consumption
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symptoms of colorectal cancer
changes in bowel habits, abd pain, bloody stool, unintentional weight loss, diarrhea, constipation, incomplete evacuation
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CRC screening should begin at age -
45-75, 76-85 individual based
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colonoscopy should be done how often
every 10 years
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flexible sigmoidoscopy
evaluates lower 1/3 of colon, combine w/FIT, yrs vary
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CT Colonography
x ray + computers produce images or the colon, every 5 years
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Types of stool tests
gFOBT
FIT
Stool DNA Test
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gFOBT
uses chemical guaiac to detect blood in the stool, yearly
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FIT
fecal immunocompromised test, uses antibodies to detect blood in stool, yearly
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Stool DNA test
FIT with a test that detects altered DNA in stool, every 3 years
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Upper Gastrointestinal Bleeding is cause by
PUD, Gastritis/esophagitis/duodenutis, esophageal varices, angiodysplasia, malignancy, mallory-weiss tears
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Lower Gastrointestinal Bleeding caused by
infection, diverticulosis, hemorrhoids, anal fissures, ischemic colitis, IBD, radiation damage
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symptoms of GI bleeding
tachycardia, hypotension, rectal bleeding, hematemesis, abd pain
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diagnosis GI bleeding
CT, endoscopy, colonoscopy
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LGIB is more common in? why?
males - vascular diseases and diverticulosis
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most common GI bleed
Upper GI bleed
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Bariatric surgery
altering digestive system to help you los weight
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weight related diseases
diabetes, heart disease, sleep apnea, NASH
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risks of Gastric surgery
bleeding, blood clots, infection, risk of anesthesia, lung/ breathing problem, leaky gut, nausea, vomiting, dumping syndrome, gallstones, hernia, bowel obstruction
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The GI system ______ ______ as we age
slows down
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slowing of GI system causes food to move ____ through the GI tract
slowly
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Slow movement of food through the GI tract leads to
dysphagia, gastroparesis, constipation, diverticulosis, ulcers, polyps, GERD
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Pelvic floor biofeedback therapy helps with
constipation, abdominal distention, bloating
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Abdominal massage helps with
GERD, adhesions, SIBO
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diaphragmatic breathing helps with
IBS
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Regular exercise has been shown to decrease
colon cancer, diverticular disease, and constipation
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exercise increases
intestinal activity
76
consider alternatives to abdominal massahes for people in
post op
77
barriers to management
missed appointments, mental health, finances, work scheduling issues, pain, transportation
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