1glaucoma patho and symptoms
fluid overproduction or insufficient drainage; peripheral vision changes
2glaucoma evaluation
eye puff test for intraocular pressure (IOP)
3open angle glaucoma
less severe, chronic, progressive
4OA glaucoma risk factors
diabetes, FH, age, african and south american
5angle closure glaucoma
medical emergency, complete occlusion, leads to blindness, painful
6meds for angle closure glaucoma
mannitol, latanoprost
7latanoprost side effect
causes iris to turn brown
8glaucoma eye drop side effects
burning in eyes; this is normal and expected
9adverse reactions and considerations irt timolol (a beta blocker)
decreased HR + BP; use caution in patients with asthma
10otitis externa prevention
dry ears w/ washcloth or cool air, don't wear earplugs a lot, don't remove earwax
11why don't we always treat minor ear infections in children?
they can resolve on their own
12management of dry AMD
vitamins A, E, and C and zinc; laser therapy; nothing is curative
13acne prevention
gentle cleansing soap + water BID, benzoyl peroxide
14atopic dermatitis meds
corticosteroids
15herpes zoster virus treatment
acyclovir
16risk factors for skin cancer
tanning beds, age, sun exposure, FH, genetics, smoking
17functions of skin
temp control, protection (first line of defense), vitamin D production, drug absorption
18impetigo s/s and treatment
bacterial infection; honey colored crust on ruptured vesicles; antibiotics
19isotretinoin consideration
severely teratogenic, must use 2 forms of BC and sign form stating BC use
20psoriasis s/s and comorbidity
silvery scales, autoimmune disorder, psoriatic arthritis
21psoriasis treatment and consideration r/t treatment
Humira/corticosteroids (cause increased risk of infection)
22endogeneous cholesterol
produced in liver
23niacin use and considerations
lower LDLs; causes flushing- use ER niacin to prevent
24lifestyle changes for hyperlipidemia
stop smoking, lower saturated fats, exercise
25gemfibrozil MoA and considerations
protein binding; increases effect of warfarin and therefore bleeding risk
26lipid panel
want LDL, VLDL, triglycerides LOW; want HDL HIGH
27statins considerations
give at night (cholesterol more active at night); monitor for rhabdomyolysis (muscle pain/aches)
28UTI s/s
dysuria, polyuria, nocturia, hematuria, cloudy urine, foul smell, increased WBCs, abdominal cramping, fever, decreased appetite, kidney pain, confusion in elderly
29pyelonephritis s/s
upper UTI in kidneys, flank pain, fever, dysuria
30nitrofurantoin lab to monitor
creatinine clearance (contraindicated if <60)
31UTI prevention
loose clothing, wipe front to back, hydrate, pee after sex, no baths/hot tubs, fragrance free soaps
32most common mechanism of drug transport across cell membrane
direct penetration
33drug elimination
kidneys primarily, respiratory secondary
34goal of drug therapy
maximum effect with minimum harm
35blood brain barrier
prevents some drugs from crossing easily
36first pass effect
activation or inactivation of drugs by the liver when taken orally
37poor elimination leads to
higher risk for toxicity
38cholinergic antagonists
decrease parasympathetic response (increases BP, HR, RR, dilates pupils, decreases digestion)
39antidotes to know
vitamin K for warfarin, naloxone for opioids
40blood gas compensation
respiratory (fastest) & renal (most effective)
42nephron primary function
filtration
43hyperkalemia treatment
insulin w/ glucose, kayexalate
44hypokalemia treatment
potassium; bananas, avocados
45furosemide use and adverse effects
fast acting, treats pulmonary edema, causes increased urination, ototoxic, hypokalemia
46aminoglycoside adverse effects
ototoxicity
47secondary infection
d/t immunosuppression from another infection; superinfection is one type d/t resistant bacteria
48labs to monitor for nephrotoxicity
BUN and creatinine
49tetracyclines considerations
causes photosensitivity; binds to Ca- can cause fetal harm and tooth discoloration
50vancomycin use and considerations
treat MRSA and C. diff; red man syndrome- monitor airway and slow the med
51anaphylactic reaction to ABX
stop infusion, check airway, call doc, administer epi, antihistamine
52shingles precautions, treatment, considerations
contact precautions, treat w/ acyclovir, rash doesn't cross midline
53HIV
TD4 cells, lower WBCs
54AIDS
secondary infection is main cause of death
55s/s of RHF
peripheral edema
56s/s of LHF
pulmonary edema
57digoxin toxicity and management
green halos, draw labs, digoxin immune fab
58cardiac conduction pathway
SA node, AV node, bundle of HIS, L+R bundle branches, Purkinje fibers
59ACE-Inhibitors use and side effect
treat HTN; persistent, dry cough
60nitro use, consideration, and side effect
vasodilator, monitor BP, headaches
61stable angina vs unstable angina
stable: pain goes away at rest; unstable: pain doesn't go away
62warfarin lab to monitor
PT INR