Chapter 7

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1
Amphipathic
Hydrophobic tail +hydrophilic head (ex. phospholipids)
2
Fluid Mosaic Model
A membrane is a fluid structure with a “mosaic” of various proteins embedded in it
3
Integral Proteins
Penetrate hydrohobic interior
4
Transmembrane Proteins
Span across membrane
5
Cell-cell Recognition
Ability of cell to distinguish nearby cells from each other (important for organizing cell tissues + rejecting foreign cells)Facilitates passage of water through membrane
6
Glycolipids
Carbs covalently bodned to lipids
7
Glycoproteins
Carbs covalently bonded to proteins
8
Selective Permiability
Cell membrane allows some substances easier entrance than others
9
Channel Proteins
Have a hydrophilic channel that can be used as a tunnel through membrane
10
Aquaporins
Facilitates passage of water through membrane
11
Carrier Proteins
Hold passengers + change shape to carry across membrane
12
Transport Proteins are...
Selective of substances they carry (important for selective permeability)
13
Difussion
Movement of particles of any susbtance so that they spread out into available space (spontaneous + follows concetration gradient)
14
Concetration Gradient
Substance moves from more concetrated area to less concetrated area
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Passive Transport
Diffusion of substance across membrane requiring no energy
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Osmosis
Diffusion of free water across a selectively permeable membrane
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Tonicity
Ability of surrounding solution to cause a cell to gain or lose water
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Isotonic
Causes no net movement of water across membrane (same amount of water)
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Hypertonic
More nonpenetrating solutes, more tonicity (more water)
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Hypotonic
Less nonpenetrating solutes, less tonicity (less water)
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Osmoregulation
Control of solute concetrations and water
22
Cell is turgid...
In hypotonic solutions
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Plant cell is flaccid...
In isotomic solutions because no water movement occurs
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Plasmolysis
Occurs in hypertonic solutions - plant cell shrivels and dies
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Facilitated Diffusion
Polar molecules and ions diffuse passively with transport proteins
26
Ion Channels
Channel proteins that transpor ions - can function as gated channels (open or close in response to a stimulus)
27
Active Transport Proteins
Can move solutes against the concetration gradient - from low to high concetration
28
Membrane Potential
Voltage (electrical porteintial energy) across a membrane
29
Electrochemical gradient
The chemical and electrical forces that power the diffusion of ions across a membrane = ions diffuse along electrochemical gradient
30
Electrogenic Pump
Transport protein that generates voltage across a membrane
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Cotransport
Transport protein combines "downhill" diffusion of solute with "uphill" transport of another substance against its concetration gradient
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Exocytosis
Secretion of certain molecules from cell by the fusion of vessicles with plasma membrane
33
Endocytosis
Cell takes in molecules and particulate matter by forming new vesicles from plasma membrane
34
6 Major Functions of Membrane Proteins
Transport
Enzymatic activity
Signal transduction
Cell-cell recognition
Intercellular joining
Attachment to the cytoskeleton and extracellular matrix (ECM)
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