closeout drugs

lisinopril

prinivil, zestril

hypertension, heart failure, myocardial infraction

qd

dry cough, dizziness, hyperkalemia, angioedema (rare)

bbw: avoid pregnancy (fetal toxicity), caution with salt substitutes and potassium, monitor bp

losartan

cozaar

hypertension, diabetc nephropathy

qd

dizzines, dry cough, hyperkalemia, angioedema (rare)

bbw: avoid pregnancy (fetal toxicity), caution with salt substitutes and potassium, monitor bp

hctz

microzide, hydrodiuril

hypertension edema

AM

polyuria, dizziness, photosensitivity, hyperglycemia, hypokalemia

alcohol may exacerbate orthostatic hypotension, monitor bp

amlodipine

norvasc

hypertension, angina, coronary artery disease

qpm

peripheral edema, dizziness, flushing, fatigue

monitor bp, be careful getting up at night to urinate

carvedilol, metoprolol succinate

coreg

hypertension, heart failure

w/ food

orthostatic hypotension, fatigue, sexual dysfunction, bradycardia, mask hypoglycemia symptoms

do not abruptly stop, caution in asthma

toprol xl

hypertension, heart failure, angina

w/ food

orthostatic hypotension, fatigue, sexual dysfunction, bradycardia, mask hypoglycemia symptoms

do not abruptly stop, caution in asthma

rosuvastatin, atorvastatin

crestor

hypercholeserolemia, hypertriglyceridemia, cardivascular event prevention

qpm

myopathy, hepatic enzyme elevation

modifiable risk factors for atherosclerosis, pregnancy category x

lipitor

hypercholesterolemia, hypertriglyceridemia, cardiovascular event prevention

qpm

myopathy, hepatic enzyme elevation

modifiable risk factors for atherosclerosis, avoid grapefruit juice, pregnacy category x

albuterol hfa

proair, ventolin, proventil

asthma, bronchospasm

1-2 inhalations q4-6hr prn

tremor, nervousness, palpitations, tachycardia, upper respiratory infections

inhalation technique, spacers, step up treatment if using >2times/week

umeclidinium/vilanterol

anoro ellipta

copd

qd

upper respiratory infections, pharyngitis, xerostomia

inhalation technique

budesonide/formoterol, fluticasone/vilanterol, fluticasone/salmeterol

symbicort

asthma, copd

bid

thrush, upper respiratory infections, pharyngitis

inhalation technique, rinse mouth after use

breo ellipta

asthma, copd

qd

thrush, headache, upper respiratory infection, nasopharyngitis, backache

inhalation technique, rinse mouth

advair diskus

asthma, copd

bid

headache, upper respiratory infection, nausea, dizziness, musculoskeletal pain

inhalation technique, rinse mouth

tiotropium respimat

spirivia respimat/handihaler

copd, asthma

qd

upper respiratory infection, xerostomia, urinary retention

inhalation techniqe, priming

montelukast

singulair

asthma, allergies

qd hs

upper respiratory infection, xerostomia, urinary retention

cough, headache, may cause depression, suicidal thoughts, hallucinations

metformin

glucophage

t2dm

w/ food

flatulence, gi upset, vit b12 deficiency, bbw: lactic acidosis

avoid excess alcohol, start low, go slow to avoid gi upset, lifestyle modifications

glargine

lantus, basaglar, toujeo

t1dm, t2dm

qd

hypoglycemia, weight gain, injection side rash, pruritis, lipodystrophy

injection technique, rotate injection site, understand hyper/hypoglycemia, management plan, storage, expiration

semaglutide

ozempic

t2dm, weightloss

q week

dyspepsia, gi upset, decreased appetite, weightloss, injection site rash, pruritis, lipodystrophy

injection technique, rotate injection site, storage(fridge), expiration date(56days)

canagliflozin

inovokana

t2dm

prior to first meal of day

uti, polyuria, bbw: lower limb amputations, hypotension

monitor for uti

varenicline

chantix

smoking cessation

day 1-3: 0.5mg qd, day 4-7: 0.5mg bid, beyond: 1mg bid w/ water

nausea, vivid, unusual dreans, insomnia, bbw: suicidal ideation, seizures

report mood changes, limit alcohol

apixaban

eliquis

atrial fibrillation, post op venous thomboprophylaxis

bid

increased risk of bleeding

prevent blood clots, increased risk of bleeding

hydrocodone/acetaminophen, oxycodone, tramadol

norco, vicodin

pain

prn

constipation, sedation, bbw: respiratory depression, bbw: neonatal opiod withdrawl syndrome

avoid driving/operating heavy machinery, avoid alcohol/cns depressants, otc laxatives, abuse and dependence, bbw: 3-4g/day of tylenol

roxicodone,oxyir, oxycontin

pain

prn

constipation, sedation, bbw: respiratory depression, bbw: neonatal opiod withdrawl syndrome

avoid driving/operating heavy machinery, avoid alcohol/cns depressants, otc laxatives, abuse and dependence

ultram

pain

prn

constipation, sedation, flushing, dizziness, bbw: respiratory depression, bbw: neonatal opioid withdrawl syndrome

avoid alcohol/operating heavy machinery, avoid alcohol/cns depressants, otc laxatives, abuse and dependence

cyclobenzaprine

flexeril

muscle spasms

prn

somnolence, dry mouth

avoid driving/operating heavy machinery, avoid alcohol/cns depressants