1what is the respiratory system
the collection of tissues and organs that allow us to undergo ventilation in order to create a concentration gradient of gases between our lungs and bloodstream
2another word for ventilation
breathing
3Name the parts of respitroy anatomy
nose, mouth, larynx, lung, diaphragm, pharynx, trachea, bronchi, bronchiole, alveoli
5Alveoli
inside the lungs; the target destination for inhaled oxygen and the drop off point for carbon dioxide
6what is the relationship between alveoli and surface area
more alveoli = more surface area
7how many layers of cells make up the wall of the alveoli?
one layer of cells
8what are the cells called that make up the wall of the alveoli
type 1 pneumocytes
9How does one layer cells benefit gas exchange?
Having lung tissue and capillary tissue only one cell layer thick means gases have only a very short distance to travel
10The capillaries contain contirnously moving bloood moving already slowly around the alveoli. what is the benefit of this design?
Slower movement gives more time for gases to be exchanged. The continuous flow of blood means there will always be a concentration gradient maintained, carbon dioxide being exhaled and fresh oxygen being loaded into the bloodstream for transport
11what quality of the alveoli wall makes it special? Why is it important?
Note: the lining of the alveoli is moist, which allows gases to dissolve and remain dissolved for transport!
12plural of alveoli
alveolus
13what type of diffusion does the gas exchange in alveoli have; why?
simple diffusion ; ensure this happens as easily and efficiently as possible
14where is the concentraion of oxygen higher? in blood or alveoli
alveoli
15if oxygen is higher in the alveoli, that means carbon dioxide is higher (concentration) in...
blood
16where does the carbon dioxide in the blood come from?
This carbon dioxide was produced via cellular respiration in our tissues. It is a waste product that can now be exhaled
17how is carbon dioxide carried by the blood?
1) dissolved CO2 in plasma
2) bound to the protein hemoglobin in red blood cells (at different site than oxygen binds)
3) carbon dioxide reacts with water to form carbonic acid which then dissociates into bicarbonate ions (and H+)
18why does the pH of blood decreases in venous blood during exercise?
the carbon dioxide reacting with water in the blood creates carbonic acid, which releases H+
19what protein does the red Blood Cells?
hemoglobin
20another name for red blood cells (RBC)
erythrocytes
21how many molecules of oxygen can a hemoglobin carry
4
22how does increasing the partial pressure of oxygen affects the percent saturation of hemoglobin?
Increasing the partial pressure of oxygen increases the percent saturation of hemoglobin
23how does high altitude affect hemoglobin saturation
Low pO2 means low oxygen % saturation of hemoglobin -- this is why it is more common to feel dizzy and lightheaded at higher altitudes!
24when does the hemoglobin become saturated
when the pO2 is high in the blood, hemoglobin will become saturated (pick up oxygen)
25When pO2 is low, hemoglobin unbinds oxygen? Why would this be the case near a muscle?
Near a muscle, the oxygen would have been used to undergo cellular respiration to create ATP energy.
26what is the diff between fetal hemoglobin and adult hemoglobin in terms of oxygen saturation
Fetal hemoglobin reaches a higher % saturation of oxygen at lower pressures than adult hemoglobin (percent saturation of hemoglobin is reached more quickly)
27what is the Bohr shift
explains the increased release of oxygen by hemoglobin in respriing tissues
28in oxygen dissociation curve, when temp is down, curve is shift to...
left
29in oxygen dissociation curve, when Pco2 is down, curve is shift to...
left
30in oxygen dissociation curve, when pH is up, curve is shift to...
left
31in oxygen dissociation curve, when temp is up, curve is shift to...
right
32in oxygen dissociation curve, when Pco2 is up, curve is shift to...
right
33in oxygen dissociation curve, when pH is down, curve is shift to...
right
34why does pH increase during excerise
More carbon dioxide is produced in cellular respiration, leading to more carbonic acid in the blood and therefore a lower pH
35when the curves shifts to the right oxygen will unbind from hemoglobin more readily. How does this help muscles during exercise?
This ensures quicker and easier replenishment of oxygen at the muscles, which need the O2 molecules to keep up with the increased energy demand
36hemoglobin has a _____ affinity for carbon monoxide than for oxygen and co2
higher
37What happens if yu inhale carbon monoxide
RBCs are quickly saturated with this gas and oxygen/carbon dioxide can no longer be exchanged at the lungs or other body tissues.
38ventilation
the mechanical process by which the lungs inflate and deflate with air. This happens due to the contracting and relaxing of the diaphragm, internal, and external intercostal muscles.
39respiration
the process by which gases are exchanged in the lungs and used by cells to create ATP energy.
40the shape of the diaphragm during inhalation
flat
41the rib muscles during inhalation
contract
42the rid cage moves during inhalation
up and outwards
43the volume of chest cavity during inhalation
increase
44the pressure of the chest cavity during inhalation
decreases
45the shape of the diagphragm during exhalation
dome shape
46the rib muslces during exhalation
relax
47the rib cage movement during exhalation
down and inwars
48the volume of chest cavity during exhalation
decreases
49the pressure of the chest cavity during exhalation
increases
50diaphragm ______ during inhalation
contracts
51diagphrarm _____ during exhalation
relaxes
52antagonistic pairs
muscles that influence each others elongation
53example of antagonistic pair
When muscles are relaxed, they are elongated. However, this elongation is passive and caused by the contraction of another muscle.
54why is respitory muscles considered antagonistic pair
The contraction of one results in the elongation of the other. When the external intercostal muscles contract during inhalation, the internal intercostal muscles relax and elongate. During exhalation, the external intercostal muscles relax and lengthen due to the contraction of the internal intercostal muscles.
55how is pH of blood decreased
when production of carbon dioxide is increased
56what part of the brain detects when the blood pH falls to low?
chemoreceptors in the medulla
57what pH level sends signals to the medulla to increase rate of ventilation
7.35
58what causes lung cancer
smoking/Vaping
Secondhand smoke
Air pollution
Radon gas exposure
Asbestos, silica, or other inhaled solids
59what is the consequences of lung cancer
Breathing difficulties/Persistent coughing
Chest pain
Loss of appetite/Weight loss
Fatigue
60emphysema
condition caused by an immune response to irritants in the lung tissue that causes a loss of elasticity and holes in alveolar walls.
61symtons of emphysema
shortness of breath, rapid breathing, and fatigue.
62treatments of emphysema
Treatments include inhaled steroids to improve airflow or oxygen supplements.
63type 1 vs tpe 2 pneucytes
Type 1 pneumocyte: The cell responsible for the gas (oxygen and carbon dioxide) exchange that takes place in the alveoli. ...
Type 2 pneumocyte: The cell responsible for the production and secretion of surfactant