BIO 112 Chapter 3 Proteins/Nucleic Acids

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1
What are the most structurally complex molecules?
Proteins
2
What are proteins polymers?
Polypeptides
3
What are nucleic acids polymers?
DNA and RNA
4
Name the 2 kinds of nitrogenous bases...
Purines and Pyrimidines
5
What is the difference between ribose and deoxyribose pentose sugar?
The lack of an oxygen atom in deoxyribose.
6
What compounds does Purine consist of?
Adenine and Guanine
7
What are the 2 types of pentose sugars?
Ribose and Deoxyribose
8
What are the 3 basic components of nucleotides?
Pentose sugar, Nitrogenous bases, Phosphate groups
9
What compounds does Pyrimidine consist of?
Cytosine, Thymine, Uracil
10
How do nucleic acids synthesize?
By connecting the pentose sugar of 1 nucleotide to the phosphate group of the next, creating H2O, creating a Phosphodiester linkage.
11
What are nucleic acids monomers?
Nucleotides
12
What does the tertiary level consists of?
Interactions between R groups of the polypeptide, hydrophobic interactions, H bonds, Ionic bonds,Disulfide bridges
13
How do quanternary structures begin?
From the aggregation of 2 or more polypeptide subunits
14
What does the Quaternary level consists of?
Prosthetic groups (conjugated protein)
15
Where are disulfide bridges found and what are their function?
Found in tertiary level, stabilizes the structure
16
What needs to happen to a polypeptide for it to become a protein?
The polypeptide needs to get coiled or bundled up in order to be considered a protein.
17
What are 2 types of secondary structures?
Alpha helix and Beta sheeted
18
What does the secondary level structure consist of?
Segments of repeated folds and coils, H bonds, Polypeptide backbone.
19
What are the 4 levels of structure?
Primary, Secondary, Tertiary, Quaternary
20
What does an amino group look like?
H-N-H
21
Name at least 3 prosthetic groups (conjugated protein) ?
Phosphoprotein, Lipoprotein, Glycoprotein
22
What can alter protein conformation?
Alterations in pH, salt concentration, temperature.
23
What is another name for protein processing or going through the 4 levels of structures?
Conforming
24
How many polypeptides does hemoglobin have?
4 polypeptides
25
How is a peptide bond formed?
Occurs when an amino acid's amino group loses an H atom and another amino's acid carboxyl group loses an OH to form water and create a peptide bond.
26
What reaction is Amino Acids joined together by?
Dehydration reaction
27
What else can a central carbon be called?
Alpha carbon
28
What does a Carboxyl group look like?
OH-C=O
29
What is another name for variable R group?
Side chain
30
What is a basic amino acid group made of?
Central carbon, H atom, Carboxyl group, NH2 group, a variable R group
31
At what structure level do polypeptides become proteins?
Tertiary
32
What are polypeptides?
A strand of amino acids
33
Proteins monomers?
Amino acids
34
After a peptide bond happens what are the ends called?
Amino end (N terminus) and Carboxyl end (c terminus)
35
Enzymes relate to what macromolecule?
Proteins
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