1The scientific study of how the brain and nervous system influence behavior, thoughts, and emotions.
Behavioral neuroscience
2A systematic process that scientists use to observe, ask questions, and test explanations about the natural world. This helps ensure that conclusions are objective, evidence-based, and repeatable.
Scientific method
3Aristotle's opinion on the brain and heart
He thought mental capacities came from the heart, and the brain was just a cooling system for hot blood from the heart.
4What theory did Descartes popularize?
Dualism, the idea that humans have an immaterial soul governing the body from a contact point. He described the human body in terms of a machine, but believed free will and moral choice couldn't arise from a machine.
5What theory did Franz Gall start?
Phrenology, the idea that bumps on the skull are the enlargement of certain brain regions with certain functions. This was debunked, but established localization of function.
6The concept that different brain regions specialize in specific behaviors.
Localization of function
7The part of a neuron that receives input from other neurons.
Dendrites
8Where the nucleus resides, this part of the neuron integrates all the incoming signals.
Soma/cell body
9The cell’s control center that contains the genetic material (DNA) and regulates the cell’s activities.
Nucleus
10A cone shape on the cell body, from which the axon extends.
Axon hillock
11A nerve fiber extension on a neuron, which can be used to send signals over long distances.
Axon
12The part of a neuron for signal output, contains neurotransmitters.
Axon terminals
13These neurons convey sensory experiences to the brain and can come in a variety of shapes.
Sensory neurons
14These neurons send signals from the brain to control movement and are often big with long axons.
Motor neurons
15These neurons receive signals from and deliver signals to other neurons, they generally have short axons.
Interneurons
16These neurons don't have dendrites and their cell body branches off from the axon, they transmit info about sense of touch or pain to the spinal cord.
Unipolar neurons
17These neurons have 1 dendrite and are commonly sensory neurons.
Bipolar neurons
18These neurons have many dendrites.
Multipolar neurons
19A tiny gap between neurons through which the presynaptic neuron sends neurotransmitters to signal to the postsynaptic neuron.
Synapse
20Hollow spheres containing neurotransmitters, sent by the presynaptic neuron across the synapse.
Vesicles
21Molecules sent across the synapse by the presynaptic neuron, they send either an excitatory or inhibitory signal to the postsynaptic neuron.
Neurotransmitters
22These are part of the postsynaptic neurons, they capture and react to neurotransmitters.
Receptors
23The gaps in an axon's myelin sheath, signals jump from node to node.
Nodes of Ranvier
24A glial cell that myelinates axons in the brain and spinal cord.
Oligodendrocyte
25A glial cell that myelinates axons in the PNS.
Schwann cell
26A fatty substance on axons that speeds up action potentials.
Myelin
27Star-shaped glial cells that form the blood brain barrier and the outer membrane of the brain, stop blood and large molecules from getting into brain regions, get rid of waste in the brain, and provide nutrients from blood to the brain regions.
Astrocytes
28Tiny, mobile cells that eat up infectious agents and debris in the brain.
Microglia
29Glial cells that have some functional receptors and can contact neurons at nodes of Ranvier or synaptic terminals. Some can even fire action potentials.
NG2 cells
30This spanish anatomist established the neuron doctrine, that neurons and other brain cells are structurally, functionally and metabolically independent, and information is transmitted between neurons across tiny gaps.
Santiago Ramon y Cajal
31This nervous system includes the brain and spinal cord.
Central nervous system
32This nervous system includes nerves throughout the body.
Peripheral nervous system
33This nervous system has nerves connecting the brain and sensory/motor systems.
Somatic nervous system
34This nervous system has nerves connecting primarily to the internal organs.
Autonomic nervous system
35This system prepares the body for immediate action.
Sympathetic nervous system
36This system helps the body rest and prepare for future action.
Parasympathetic nervous system
37Toward an area of interest
Afferent
38Away from an area of interest
Efferent
39The plane dividing an object into left and right
Sagittal plane
40The plane dividing an object into front and back
Coronal plane
41The plane dividing an object into top and bottom
Horizontal plane
42Toward the back (or top of brain)
Dorsal
43Toward the belly (or bottom of brain)
Ventral
44Toward the front
Rostral/anterior
45Toward the back
Caudal/posterior
48Towards the middle
Medial
49Towards the side
Lateral
50On the same side
Ipsilateral
51On a different side
Contralateral
52Top of the brain, containing the telencephalon and the diencephalon.
Forebrain
53Middle of the brain, containing the mesencephalon.
Midbrain
54Bottom of the brain, containing the metencephalon and myelencephalon.
Hindbrain
55Brain region containing the cerebral cortex, basal ganglia, and limbic system.
Telencephalon
56Brain region containing the thalamus and hypothalamus.
Diencephalon
57Brain region containing the midbrain (superior/inferior colliculi and substantia nigra).
Mesencephalon
58Brain region containing the pons and cerebellum.
Metencephalon
59Brain region containing the medulla.
Myelencephalon
60A group of cell bodies in the CNS
Nuclei
61A group of cell bodies in the PNS
Ganglia
62A group of axons in the CNS
Tracts
63A group of axons in the PNS
Nerves
64Ridges of tissue in the cerebral cortex
Gyrus / gyri
65Crevices of tissue in the cerebral cortex
Sulcus/sulci
66Cell bodies in the brain/spinal cord (color)
Gray matter
67Myelinated axons in the brain/spinal cord (color)
White matter
68This term refers to the midbrain, pons and medulla.
Brainstem
69This part of the hindbrain drives essential processes such as breathing and heart rate, and is also the point of origin for some cranial nerves.
Medulla
70This part of the hindbrain handles things like sleep cycles, dreams, some motor and sensory work, and also relays signals between the cerebellum and cerebral cortex.
Pons
71This part of the hindbrain is made of 3-layer tissue, and handles tasks like motor coordination, balance, and some cognitive learning.
Cerebellum
72This part of the midbrain is responsible for visual processing.
Superior colliculi
73This part of the midbrain is responsible for sound processing.
Inferior colliculi
74This part of the midbrain is responsible for perception of pain, the dorsal part helps with active coping while the ventral part helps with passive coping.
Periaqueductal gray
75This part of the midbrain has neurons that release dopamine in the forebrain, loss of these neurons can lead to Parkinson's Disease.
Substantia nigra
76This part of the telencephalon is made of 6-layer tissue and features 4 lobes, it is responsible for complex cognition.
Cerebral cortex
77This lobe is in the front of the cortex, it is important for movement and high-level cognition.
Frontal lobe
78This lobe is behind the frontal lobe, it is important for sense of touch and spatial awareness.
Parietal lobe
79This lobe is on either side of the cerebral cortex, it is important for hearing, language, and memory.
Temporal lobe
80This lobe is in the back of the cerebral cortex, it is important for vision.
Occipital lobe
81This part of the diencephalon helps govern motivated behaviors (sex, aggression, hunger, etc) and can regulate hormones.
Hypothalamus
82This part of the hypothalamus is how it regulates hormones.
Pituitary gland
83This part of the diencephalon directs all sensory input (except smell) to the correct cortex region, and receives motor commands from the cortex.
Thalamus
84This part of the telencephalon is critical for movement.
Basal ganglia
85This part of the basal ganglia helps with goal-directed learning, working memory, visual beauty perception, and might be related to OCD.
Caudate
86This part of the basal ganglia is related to motor skills and planning.
Putamen
87This part of the basal ganglia helps with keeping movement smooth and coordinated.
Globus pallidus
88This part of the telencephalon features structures such as the amygdala and hippocampus.
Limbic system
89This part of the limbic system does rapid evaulation of sensory input, as well as emotional responses to external stimuli.
Amygdala
90This part of the limbic system helps with spatial navigation and episodic memory.
Hippocampus
91Chambers in the brain filled with CSF (there are 4 of them)
Ventricles
92This liquid cushions the brain from minor blows to the head, conveys nutrients, signals chemicals, and picks up waste matter.
Cerebrospinal fluid / CSF
93This system, made of astrocytes, keeps blood and large molecules out of the brain.
Blood brain barrier
94This is a way of visualizing the brain that includes mapping the diffusion of water within axons to visualize axonal fiber tracts.
Diffusion tensor imaging / DTI
95A method of visualizing brain activity using a cap that reads electrical signals from different parts of the brain and tracks them as brain waves.
Electroencephalography / EEG
96This method of visualizing brain activity measures magnetic fields coming from neurons to construct real-time maps of brain activity.
Magnetoencephalography / MEG
97This method of visualizing brain activity tracks radioactive chemicals inserted into the bloodstream and maps where they are used, in order to find out which brain regions are most active.
Positron emission tomography / PET
98This method of visualizing brain activity is the most spatially precise, it uses quickly oscillating magnetic fields to detect regional changes in brain metabolism, especially oxygen use / blood flow.
Functional magnetic resonance imaging / fMRI
99Name for using patients to learn about neuroscience through causal inference.
Lesion methods
100This foreman survived a brain injury where a metal rod was driven through his skull, destroying his frontal lobe, but after the injury he became impulsive, unlikeable and could no longer hold down a job.
Phineas Gage
101Directly turning on/off a certain brain region, often done electrically, these methods can establish causality.
Stimulation methods
102This method uses focal magnetic currents using electromagnetic coils to directly stimulate part of one's cortex, it can establish causality.
Transcranial magnetic stimulation / TMS
103A method to control behavior that has been tested on animals. A virus containing a light-sensitive protein is inserted in an animal's brain, then a fiber-optic cable is inserted alongside an electrode, and light of a specific wavelength can open ion channels in neurons, allowing scientists to turn parts of the brain on or off.
Optogenetics
104A stain scientists use on neurons to see all the cell bodies and their size in a specific tissue section.
Nissl stain
105A stain scientists use on neurons that only highlights certain neurons, but shows them in great detail.
Golgi stain
106This method can visualize which cells are expressing a gene and where that gene is active, using radioactive RNA or DNA to label neurons in which a gene of interest has been turned on.
In situ hybridization
107A method of visualizing the brain where radioactive drugs are taken, then thin slices of brain tissue are placed alongside photographic film, the radioactivity takes a "picture" of the brain with highlights in areas where the drug is concentrated.
Autoradiography
108A method of visualizing specific proteins in tissue samples of the brain, involving creating antibodies to a certain protein, these attach themselves to a protein and reveal the distribution of neurons in the protein.
Immunohistochemistry
109The branch of physiology that studies the functions of the nervous system and its mechanisms, playing a crucial role in understanding neurological and psychiatric conditions.
Neurophysiology
110A tiny electrode that can record or deliver electrical signals from a very small area, such as a single neuron.
Microelectrode
111The point where the electrical difference across a neuron's membrane is balanced, generally -50-80 mV.
Resting potential
112Negatively charged ions
Anions
113Positively charged ions
Cations
114These ion channels are closed unless an axon is depolarized enough, in which case they open.
Voltage-gated channels
115These ion channels only open in response to a certain neurotransmitter.
Ligand-gated channels
116These proteins in a neuron pump 3 sodium cations out of the cell for every 2 potassium cations pumped in, they use up a lot of energy.
Sodium-potassium pumps
117This kind of signal increases the chance of the postsynaptic neuron becoming depolarized enough to reach the threshold.
Excitatory postsynaptic potential (EPSP)
118This kind of signal decreases the chance of the postsynaptic neuron reaching the threshold, and helps to hyperpolarize it.
Inhibitory postsynaptic potential (IPSP)
1195 steps of an action potential
Resting membrane potential, EPSP, AP rise, AP fall, refractory period
120What effect does myelin have on action potentials?
Saltatory conduction / APs jump from node to node.
121What disease is the result of myelin being compromised?
Multiple sclerosis (MS)
122The summation of multiple presynaptic neurons releasing neurotransmitters simultaneously.
Spatial summation
123The summation of multiple presynaptic neurons releasing neurotransmitters over time.
Temporal summation
124Substances that activate a receptor to give a response, have similar effects to a neurotransmitter.
Agonists
125Substances that block a receptor and prevent a neurotransmitter from binding to it.
Antagonists
126When neurotransmitters are absorbed back into the presynaptic neuron for future use.
Reuptake
127When special enzymes break down neurotransmitters.
Degradation
128The tendency for a substance to spread so it is less concentrated.
Diffusion