Module 32

The site where the parental DNA strands separate as the DNA duplex unwinds.

The mechanism of DNA replication in which each strand of a parental DNA molecule serves as a template for the synthesis of a new daughter strand.

An enzyme that separates the two DNA strands at the replication fork so that each strand can be copied during DNA replication.
- does this by breaking hydrogen bonds holding the pair
- proteins bind afterward to stop them from coming back together

An enzyme that relieves stress on the DNA double helix that results from overwinding or underwinding during DNA replication and transcription.
- works upstream

An enzyme that is a critical component of a large protein complex that carries out DNA replication.
- exists in all organism
- highly conserved(doesn't have much variance in different species)

A short strand of DNA or RNA; in DNA replication, RNA is used as a primer for DNA synthesis.
- starter for DNA synthesis
- made by RNA primase

A daughter strand that has its 3′ end pointed toward the replication fork, so as the parental double helix unwinds, this daughter strand can be synthesized as one long, continuous polymer.

A daughter strand that has its 5′ end pointed toward the replication fork, so as the parental double helix unwinds, a new DNA piece is initiated at intervals, and each new piece is elongated at its 3′ end until it reaches the piece in front of it.

An enzyme that joins two DNA fragments together.

The process in which a DNA polymerase can
immediately correct its own errors by excising and replacing a mismatched base.