Biology Exam 1

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1
Phospholipids: What are the main components of biological membranes?
Hydrophilic head and hydrophobic tails
2
Cell membrane function: What does the cell membrane do?
Separates intracellular and extracellular environments, anchors cytoskeleton, regulates entry/exit of substances, and facilitates cell communication
3
Fluid Mosaic Model: What does the Fluid Mosaic Model describe?
The membrane as a flexible bilayer where proteins float like icebergs in a sea of lipids
4
Factors influencing membrane fluidity: What factors influence membrane fluidity?
Degree of saturation, temperature, and cholesterol content
5
Types of cellular junctions: What are the types of cellular junctions?
Tight junctions, anchoring junctions, and communication junctions
6
Role of tight junctions: What is the role of tight junctions?
Restrict movement of substances between cells and prevent membrane proteins from migrating
7
Desmosomes: What are desmosomes?
Specialized adhesive junctions that hold cells together
8
Cell communication through junctions: How do cells communicate through junctions?
Gap junctions (in animals) and plasmodesmata (in plants) allow direct exchange of molecules
9
Types of passive transport: What are the types of passive transport?
Diffusion, facilitated diffusion, and osmosis
10
Osmosis: What is osmosis?
The movement of water across a selectively permeable membrane from low to high solute concentration
11
Hypotonic solution: What happens in a hypotonic solution?
Water moves into the cell
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Hypertonic solution: What happens in a hypertonic solution?
Water moves out of the cell
13
Isotonic solution: What happens in an isotonic solution?
No net movement of water
14
Active transport: What is active transport?
Movement of molecules against their concentration gradient using ATP
15
Sodium-potassium pump: What does the sodium-potassium pump do?
Uses ATP to move 3 Na+ out and 2 K+ into the cell
16
Types of endocytosis: What are the types of endocytosis?
Phagocytosis, pinocytosis, receptor-mediated endocytosis
17
Exocytosis: What is exocytosis?
Process of vesicles fusing with the plasma membrane to release materials outside the cell
18
Types of cell signaling: What are the types of cell signaling?
Direct contact (Juxtacrine), Paracrine, Endocrine, and Synaptic
19
Main components of cell signaling: What are the main components of cell signaling?
Ligand (signaling molecule) and receptor (molecule that binds ligand)
20
Protein kinases and phosphatases: What is the difference between protein kinases and phosphatases?
Kinase adds a phosphate group; Phosphatase removes a phosphate group
21
Types of receptors: What are the types of receptors?
Intracellular and cell surface/membrane receptors
22
Second messengers: What are second messengers?
Small molecules (e.g., cAMP, Ca2+) that relay signals inside the cell
23
Function of receptor tyrosine kinases (RTKs): What is the function of receptor tyrosine kinases?
Bind ligands, autophosphorylate, and activate intracellular signaling pathways
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Example of an RTK: Give an example of a receptor tyrosine kinase (RTK).
The insulin receptor
25
MAP kinase cascade: What is the MAP kinase cascade?
A signaling pathway that amplifies signals and regulates cell functions like differentiation and apoptosis
26
Cell Theory: What are the three parts of the Cell Theory?
All organisms are made of cells, Cells are the smallest living things, Cells arise only from pre-existing cells
27
Cell Size Limitation: What happens as the cell size increases?
Diffusion efficiency decreases and the surface area-to-volume ratio decreases, making material exchange harder
28
Basic Cell Structures: What are the basic cell structures?
Plasma membrane, cytoplasm, genetic material, and ribosomes
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Prokaryotes: What are prokaryotes?
Bacteria and Archaea
30
Prokaryotic Genetic Material Location: Where is genetic material located in prokaryotes?
In the nucleoid region (not enclosed by a membrane)
31
Bacterial Cell Walls: What are bacterial cell walls made of?
Peptidoglycan (Gram-positive: thick layer; Gram-negative: thin layer)
32
Prokaryotic Movement: How do prokaryotes move?
Some use flagella, which rotate to propel the cell
33
Unique Features of Archaea: What is unique about archaea?
They can live in extreme environments and have genes similar to both bacteria and eukaryotes
34
Eukaryotic Cells: What is a feature of eukaryotic cells?
Membrane-bound nucleus and organelles, more complex structures, and a cytoskeleton
35
Nucleus Function: What is the function of the nucleus?
Stores genetic material (DNA) in the form of chromatin
36
Nuclear Envelope: What is the nuclear envelope?
A nuclear envelope made of two phospholipid bilayers
37
Ribosome Function: What is the function of ribosomes?
Synthesize proteins
38
Ribosome Location: Where are ribosomes located?
Free in the cytoplasm or attached to the rough endoplasmic reticulum (RER)
39
Endomembrane System Components: What are the components of the endomembrane system?
Endoplasmic reticulum (RER & SER), Golgi apparatus, lysosomes, peroxisomes, vesicles
40
Rough ER Function: What is the function of the rough ER?
Protein synthesis and processing
41
Smooth ER Function: What is the function of the smooth ER?
Lipid synthesis, calcium storage, detoxification
42
Golgi Apparatus Function: What is the function of the Golgi apparatus?
Modifies, packages, and distributes proteins and lipids
43
Lysosome Function: What is the function of lysosomes?
Breaking down macromolecules and digesting foreign material via phagocytosis
44
Vacuoles: What are vacuoles?
Membrane-bound structures for storage: Central vacuole (plants), contractile vacuole (protists), storage vacuoles
45
Mitochondria Function: What is the function of mitochondria?
ATP production through oxidative metabolism
46
Chloroplast Function: What is the function of chloroplasts?
Photosynthesis in plants and some protists
47
Mitochondria and Chloroplasts Structures: What are the similarities between mitochondria and chloroplasts?
Both have double membranes, their own DNA, and ribosomes
48
Endosymbiosis Theory: What is the endosymbiosis theory?
Eukaryotic organelles (mitochondria & chloroplasts) evolved from symbiotic prokaryotes
49
Endosymbiosis Evidence: What evidence supports endosymbiosis?
Mitochondria & chloroplasts have two membranes, their own DNA & ribosomes, and bacteria-like division process
50
Cytoskeleton: What is the function of the cytoskeleton?
A network of protein fibers that maintain cell shape and movement
51
Types of Cytoskeleton Fibers: What are the types of cytoskeleton fibers?
Actin filaments, Microtubules, Intermediate filaments
52
Prokaryotic Cytoskeleton: Do prokaryotes have a cytoskeleton?
Yes, but it is different from that of eukaryotes
53
Cell Movement: How do cells move?
Crawling (actin & myosin), flagella (undulate motion), cilia (wave-like motion)
54
Cilia and Flagella Structure: What is the structure of cilia and flagella?
9 + 2 structure: 9 pairs of microtubules surrounding 2 central microtubules
55
Cell Wall Components: What are the components of cell walls?
Plants & protists: Cellulose; Fungi: Chitin
56
Extracellular Matrix (ECM): What is the extracellular matrix (ECM)?
A structure made of glycoproteins and collagen that supports and connects cells
57
ECM Communication: How does the ECM communicate with cells?
Via integrin proteins embedded in the plasma membrane
58
Why is carbon important in biological molecules?
It can form up to 4 covalent bonds with other atoms, allowing complex molecules
59
What are functional groups?
Specific molecular groups that give molecules distinct properties (e.g., hydroxyl, carboxyl)
60
What are monomers and polymers?
Monomer: A single building block (e.g., amino acid, nucleotide); Polymer: A chain of monomers (e.g., protein, DNA)
61
What is dehydration synthesis?
The process of forming polymers by removing water
62
What is hydrolysis?
The process of breaking polymers by adding water
63
What is the general formula for carbohydrates?
(CH2O)n
64
What are the main functions of carbohydrates?
Energy storage (e.g., starch, glycogen) and structural support (e.g., cellulose, chitin)
65
What are disaccharides?
Two monosaccharides linked by dehydration synthesis (e.g., sucrose, lactose, maltose)
66
What are polysaccharides?
Long chains of sugars used for storage or structure (e.g., starch, glycogen, cellulose)
67
What are the three types of nucleic acids?
DNA, RNA, and ATP
68
What are the components of a nucleotide?
A pentose sugar, a phosphate group, and a nitrogenous base
69
What are the nitrogenous bases?
Purines: Adenine (A), Guanine (G); Pyrimidines: Thymine (T), Cytosine (C), Uracil (U)
70
What base is found in RNA but not in DNA?
Uracil (U) replaces Thymine (T)
71
How are nucleotides linked together?
By phosphodiester bonds in a sugar-phosphate backbone
72
What is ATP?
Adenosine triphosphate, the primary energy currency of the cell
73
What are the functions of proteins?
Enzyme catalysis, defense, transport, support, motion, regulation, storage
74
What are proteins made of?
Polymers of amino acids linked by peptide bonds
75
What are the components of an amino acid?
Central carbon, amino group, carboxyl group, hydrogen, and R group
76
How do R groups affect amino acids?
They determine chemical properties (e.g., nonpolar, polar, charged)
77
What are the four levels of protein structure?
Primary, Secondary, Tertiary, Quaternary
78
What causes protein denaturation?
Changes in pH, temperature, or salt concentration
79
What makes lipids unique from other biomolecules?
They are hydrophobic (insoluble in water)
80
What are the two main types of lipids?
Fats (triglycerides) and phospholipids
81
What are triglycerides composed of?
1 glycerol + 3 fatty acids
82
What is the difference between saturated and unsaturated fats?
Saturated: No double bonds, solid at room temp; Unsaturated: Double bonds, liquid at room temp
83
Why are plant oils liquid at room temperature?
They contain unsaturated fatty acids
84
What are phospholipids made of?
1 glycerol + 2 fatty acids + 1 phosphate group
85
What is the structure of phospholipids?
Polar (hydrophilic) head and nonpolar (hydrophobic) tails, forming cell membranes
86
Cellular organization: What does cellular organization refer to?
The structural arrangement of cells
87
Ordered complexity: What does ordered complexity mean?
Living organisms have complex structures
88
Sensitivity (response to stimuli): What does sensitivity refer to?
How organisms respond to environmental changes
89
Growth, development, and reproduction: What does this characteristic of life involve?
The processes through which organisms grow and reproduce
90
Energy utilization: What does energy utilization refer to?
How organisms use energy to maintain their functions
91
Homeostasis: What is homeostasis?
The ability of an organism to maintain stable internal conditions
92
Evolutionary adaptation: What does evolutionary adaptation refer to?
The changes in organisms over time to better fit their environment
93
Viruses: What are viruses?
Entities that lack cellular organization and cannot reproduce independently; they require a host cell to replicate
94
Primary goal of science: What is the primary goal of science?
To understand the natural world through observation, experimentation, and reasoning
95
Inductive Reasoning: What is inductive reasoning?
Uses specific observations to form general conclusions
96
Deductive Reasoning: What is deductive reasoning?
Applies general principles to predict specific outcomes
97
Scientific method: What is the scientific method?
A systematic process involving observation, question formulation, hypothesis testing, experimentation, data collection, analysis, and conclusion
98
Scientific Hypothesis: What is a scientific hypothesis?
A proposed explanation for an observation that can be tested
99
Statistical Hypothesis: What is a statistical hypothesis?
A mathematical statement tested using data (e.g., null and alternative hypotheses)
100
Null Hypothesis (H€ ): What is the null hypothesis?
Assumes no effect or no difference (e.g., 'PLTL leadership does not affect MCAT scores')
101
Alternative Hypothesis (H• ): What is the alternative hypothesis?
Suggests an effect or a difference exists (e.g., 'PLTL leadership improves MCAT scores')
102
Independent Variable (IV): What is the independent variable?
The factor being manipulated (e.g., PLTL leadership)
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Dependent Variable (DV): What is the dependent variable?
The factor being measured (e.g., MCAT score)
104
Controls and constants: Why are controls and constants important in experimental design?
To ensure that only the independent variable is affecting the outcome
105
Qualitative Data: What is qualitative data?
Descriptive data (e.g., color, behavior)
106
Quantitative Data: What is quantitative data?
Numerical data (e.g., test scores, temperature)
107
Linear regression: What is linear regression?
A statistical method that models the relationship between a dependent and independent variable
108
Scientific conclusions: How are scientific conclusions determined?
By evaluating whether the null hypothesis should be rejected or not, interpreting the significance of results, and considering possible sources of error or limitations
109
Hypothesis in science: What can hypotheses in science be based on?
Can only be supported or rejected based on available evidence; they cannot be proven
110
Ways scientists share research findings: How do scientists share research findings?
Presentations at conferences, peer-reviewed journal articles, and academic reports












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