DOSAGE FORMS PART 3

Moisture sensitivity of soft gelatin capsule

are liquid preparations, that contain one or more chemical
substances dissolved in a suitable solvent or mixture of
mutually miscible solvents

Monophasic liquid dosage forms are represent by

where as the component present in small quantity is termed as

The component of the solution which is present in a large quantity is known as

<1

1-10

10-30

30-100

100-1,000

1,000-10,000

>10,000

solutions containing high concentration of sucrose or other sugars

nearly saturated aqueous solution of sucrose(85% w/v)
- inherently stable and resistant to the growth of microorganisms
when properly prepared and maintained

It retards oxidation because its partly hydrolyzed into reducing sugar.
It prevents decomposition of many vegetable substance because its have high osmotic pressure which prevent the growth of bacteria.
They are palatable due sweet taste.

are clear, pleasantly flavoured, sweetened hydroalcoholic solutions
intended for oral use

Alcohol content of elixirs

Aromatic Elixir, NF

are alcoholic or hydroalcoholic solutions of volatile substances
alcohol content: generally over

Uses of Spirits or Essences

Storage of Spirits or Essences

are alcoholic or hydroalcoholic solutions prepared from vegetable materials or from chemical substances

Alcohol content of tinctures

Process M

Process P

Examples of Tinctures

are liquid preparations of vegetable drugs containing alcohol as solvent, preservative or both and so made that unless otherwise specified
in an individual monograph,
- each mL contains 1 g of the standard drug

Preparation of Fluidextracts

are clear, aqueous solutions saturated with volatile oils or other aromatic or volatile substances also known as medicated waters
uses:
-flavored vehicle for water soluble drugs
- aqueous phase in some emulsions or suspensions
storage: tight, light-resistant bottles

are aqueous solutions used for its deodorant, refreshing or antiseptic effect or for control of plaque

are aqueous solutions used for treating the pharynx and
nasopharynx by forcing air from the lungs through the gargle which is held in the throat

Intended for topical application to the skin or mucous
membranes

are aqueous or oleaginous solutions in the
form of coarse droplets or finely divided solids
to be applied topically, most usually to the
nasopharyngeal tract or to the skin

locally applied solutions that constrict
pores and precipitate proteins
Aluminium acetate, aluminium
subacetate, and calcium hydroxide
topical solutions

kill microorganisms when applied to the skin or mucus membranes
Povidone-iodine, thimerosal, and
hydrogen peroxide topical solutions

influence the general
system by absorption

rectal solutions employed to evacuate the bowel

are aqueous solutions directed against a part or into a cavity of the body
- functions as a cleansing or antiseptic agent
- are frequently dispensed in the form of a powder with the directions for dissolving in a specified quantity of warm water

Liniments is also known as

are nonaqueous alcoholic or oleaginous solutions (or emulsions) of
various medicinal substances intended to be rubbed on the skin
- rubefacient, counterirritant or penetrating action