1was first isolated in 1825 by English chemist Michael Faraday from the oily residues after heating whale oil under pressure to produce a gas
used to illuminate buildings in London.
Benzene (C6H6)
2Benzene (C6H6), was first isolated in 1825 by English chemist
Michael Faraday
3In 1834, aromatic hydrocarbons were prepared from
benzoic acid
4Benzoic acid is a compound obtained by chemical degradarion of
gum benzoin
5These are related hydrocarbons
benzene and toluene
6An Austrian chemist, recognized in 1861 that most aromatic substances have formulas that can be derived from benzene by replacing one
or more hydrogens by other atoms or groups.
Joseph Loschmidt
7Is the parent hydrocarbon of the especially stable compounds known as aromatic compounds.
Benzene, C6H6
8came to mean any compound structurally derived from benzene.
aromatic
9These compounds are hydrocarbons that contain a
benzene ring as a structural unit.
Aromatic Hydrocarbons
10In addition to benzene, other examples include
toluene and naphthalene
11are either liquids or solids at room temperature;
none are gases.
arenes
12was once widely used as a solvent, but evidence
of its carcinogenic properties prompted its replacement by
less hazardous solvents.
Benzene
13The most common reactions of aromatic compounds
involve
substitution
14The most common reactions of aromatic compounds involve substitution of other atoms or groups for a ring hydrogen on the aromatic unit, or more precisely called an
electrophilic aromatic substitution reaction
15The bromination or chlorination of benzene requires a Lewis acid such as
ferric bromide or ferric chloride
16The bromination or chlorination of benzene
requires a Lewis acid such as
ferric bromide or ferric chloride
17Electrophilic iodine (I+) is obtained by treating
I2 with an oxidizing agent such as
nitric acid
18Nitration of benzene with nitric acid requires
sulfuric acid as a catalyst.
19strong acid because of the three electron-
withdrawing oxygen atoms and the stability of its conjugate base.
sulfonic acid
20places an acyl group on a
benzene ring
Friedel–Crafts acylation
21places an alkyl group on a
benzene ring.
Friedel–Crafts alkylation
22lowers blood pressure, beta blocker and antihypertensive
Propanolol
23hydantoin, anticonvulsants for seizure
phenytoin
24barbituarate, anti convulsant for seizure
phenobarbital
25NSAID, COX inhibitor
phenylbutazone
26shows inflammation, make you feel pain and fever
prostaglandins
27HMGCOA, rwductase inhibitor and antihyperlipidemia
Atrovastatin
28oral contraceptive, birth control pills
ethinylestradiol
29coumann, anticoagulants
warfarin
30activates CNS, for patient with narcoleptys (mga bigla nagdodown ang CNS)
amphetamine