1Hydrogen adds to an alkyne in the
presence of a metal catalyst such as
palladium, platinum, or nickel
2The product of the hydrogenation
reaction, therefore, is an
alkene
3Used to treat seizure disorders,
mental/mood conditions (such as manic
phase of bipolar disorder)
- alkene
Valproic Acid
4Sedative-hypnotic
- alkene
Amobarbital
5Also known as angel dust or PCP
- phenylcyclohexyl piperidine
Dissociative hallucinogenic drug used for
its mind-altering effects
- Cycloalkane and cycloalkene
Phencyclidine
6Used to control absence seizures (petit
mal)
Ethosuximide
7Anesthetic, anticonvulsant, anxiolytics,
sedative, hypnotic
Secobarbital
8A synthetic, non-steroidal form of
estrogen
- Well known teratogen and carcinogen
Diethylstilbestrol
9Manufacture of poly vinyl chloride (PVC)
Vinyl Chloride
10Manufacture of dyes and optical
brighteners, and also as phosphor
(luminescence) and a scintillator
Stilbene
11Acts as a suicide inactivator of
cytochrome P450 by covalently binding
to its heme moiety or surrounding protein
Allylisopropylacetamide
12Is a volatile, inhalational, anesthetic, and
was the first halogenated hydrocarbon
anesthetic to be introduced
Fluroxene
13Anti-leukemic agent
Ponatinib
14Antiretroviral medication used to treat
and prevent HIV/AIDS
Efavirenz
15was first isolated in
1825 by English chemist Michael Faraday
from the oily residues after heating whale oil
under pressure to produce a gas used to
illuminate buildings in London.
Benzene (C6H6)
16In 1834, aromatic hydrocarbons were prepared from
benzoic acid
17a compound obtained by
chemical degradation of gum benzoin, the
fragrant balsam exuded by a tree that grows
on the island of Java, Indonesia.
benzoic
acid (C6H5CO2H)
18an Austrian
Chemist, recognized in 1861 that most
aromatic substances have formulas that can
be derived from benzene by replacing one or
more hydrogens by other atoms or groups
Joseph Loschmidt
19is the parent
hydrocarbon of the especially stable
compounds known as aromatic compounds
Benzene
20came to
mean any compound structurally derived
from benzene
aromatic
21In addition to benzene, other
examples include
toluene and naphthalene
22are either liquids or solids at
room temperature; none are gases
arenes
23Aromatic hydrocarbons are insoluble in
water
true
24The most common reactions of aromatic
compounds involve
substitution
25is the usual temperature
0-50 C
26The bromination, iodination, and
chlorination of benzene requires a Lewis
acid such as
ferric bromide or ferric
chloride
27Electrophilic Iodine is obtained by
treating I2 with an oxidizing agent such as
nitric acid
28Nitration of benzene with nitric acid
requires
sulfuric acid as catalyst
29Protonate nitric acid and requires
nitro
30strong acid
because of the three electron-
withdrawing oxygen atoms and the
stability of its conjugate base
sulfonic acid