PART 1

30 flashcardsby Llance
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1
what the body does to the drug, how the body absorbs, metabolizes, distributes, and excretes drugs
pharmacokinetics
2
what the drug does to the body, effects of the drugs in the bodvvvvvyvvvvvvv
pharmacodynamics
3
approximately 50% if marketed drugs are
chiral
4
longer half-life; less distributed and less potentv
(R)-(+)-Warfarin
5
shorter half-life; more distributed and more potent
(S)-(-)-Warfarin
6
it is pharmaceutically inactivev
(R)-Ibuprofen
7
same molecular formula or structure but their atoms are arranged differently
chirality
8
tetratogenic which caused phocomelia
(-)(S)-thalidomide
9
sedative effects and for managing morning sickness
(+)(R)-thalidomide
10
two most important natural sources of alkanes
petroleum and natural gas
11
complex liquid mixture of organic compounds (alkanes or cycloalkanes)
petroleum
12
often found asssociated with petroleum deposits, consists mainly of methane with 80% and ethane with about 5-10%
natural gas
13
major constituent of liquefied petroleum gas, a domestic fuel
propane
14
gas choice in some areas
butane
15
why alkanes are insoluble in water?
because water is polar and alkanes are non-polar, it is goernevd by the principle of like dissolves like
16
C1-C4
Gas
17
C5-C17
Liquid
18
> C18
Solid Wax
19
at room temperature, alkanes occur as
gases, liquids and solids
20
often constitute the parts of the protective coating on leaves and fruits
alkanes
21
C27H56 and C29H50
normal alkanes
22
C31H64
main alkane of tobacco leaves
23
C29H50
main alkane of brocolli and cabbage
24
all of the bonds in alkanes are
single, covalent and non-polar
25
alkanes are relatively
inert
26
alkanes ordinarily do not react with most common acids, bases or oxidizing and reducing agents
true
27
alkanes can be used as solvents for extraction or crystallization as well as for carrying out chemical reactions of other substance because of its?
inertness
28
alkanes do not react with some reagents such as
molecular oxygen and the halogens
29
addition of O, removal of H, replacement of C-H bonds by C-O bonds
Oxidation
30
one or more hydrogen atoms of the alkanes are replaced by halogen atoms
halogenation
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