1Three phases of prenatal development
Germinal (weeks 0-2), embryonic (weeks 3-8), and fetal (week 9-birth)
2Beginning of pregnancy
Debated, some say at conception, some after about two weeks/when it becomes an embryo, and others count from the last menstural period, about 14 days before conception
3Length of pregnancy
226 days, or 38 weeks, or 9 months
4Trimesters
Division of pregnancy into three three-month periods. First is months 1-3, second is 4-6, and third is 7-9
5Due date
Based on the date of the last menstrual cycle, but often off. 37-40 weeks = full term.
6Germinal period
First 14 days/2 weeks, the zygote begins duplication and division within hours of conception. Development of the placenta and implantation occurs.
7Implantation
The shell that will become the placenta burrows into the nurturing lining of the uterus. Not simple, most zygotes do not implant
8Germinal vulnerability during prenatal development
An estimated 65% of all zygotes do not grow or implant properly
9Embryonic vulnerability during prenatal development
~20% all all embryos are aborted spontaneously (early miscarriage), commonly due to a chromosomal malformation
10Fetal vulnerability during prenatal development
~5% of all fetuses are aborted spontaneously before visibility at 22 weeks or are stillborn, more common in low-income nations
11Birth vulnerability during prenatal development
Only ~27% of all zygotes grow and survive to become living newborn babies
12Embryonic Period
Weeks 3-8, primitive streak (22 days post conception) becomes the neural tube that later forms the brain and spine of the central nervous system; the head takes shape; the eyes, ears, nose, and mouth form; the heart begins to pulse; extremities develop and webbed fingers/toes seperate; cephalocaudal and proximodistal growth is evident; both male and female potential in a tiny intersex gonad are present
13Embyro
The name for a developing human organism from about the third week through the eighth week after conception
14Cephalocaudal
Growth and development that occurs from the head down
15Proximodistal
Growth or development that occurs from the center or core (spine) in an outward direction. This directional patterns continues until puberty, when it reverses
16Fetal Period
Week 9-birth, rapid fetus growth with considerable variation, avg of 3 months, 3oz, and 3 inches, hormones guide the growth of the body and brain, and in the third month, neurological sex differences begin, overlap is common
17Fetal period: middle three months
Large body movements and vigorous leg kicks, digestive and excretory systems develop, heartbeat speeds up when fetus is awake/moving, finger/toe nails and buds for teeth form, and hair grows, brain maturation allows the fetus to reach the age of viability
18Fetal period: final three months
Neurological, respiratory, and cardiovascular systems develop, the male fetus's testicles descend, hearing adjusts to sounds, the cortex becomes wrinkled, and fontanels develop
19Apoptosis
Occurs in the finaly months of pregenancy, cell death where as many as half of all neurons die,
20Interdisciplinary research
is essential to understanding early brain development becuause true, biological, technical, and clinical experts are required
21By the third week after conception...
Specialized neural progenitor cells eventually become brain cells (neurons), which migrate to a particular brain region and specialize
22By mid-pregnancy...
Billions of neurons create ridges and depressions (gyri and sulci), allowing for a larger, more complex brain. Cortex layers are produced, back of neck, midbrain, and forebrain develop and connect, and synchronized connections between brain parts begin
23Brain development switched from the first six months to the final three, causing...
The environment to become more influential, and fewer new neurons to form and existing neurons to be affected by maternal stress, sleep, exercise, and more
24Fetal brain signals...
The release of hormones to trigger the uterine muscles
25Average labor duration for firstborn babies
12 hours
26Average labor duration for subsequent babies
7 hours
27Birthing positions
Various kinds, sitting, squatting, lying down, and water births (cultural and personal preference)
28Anoxia
Lack of oxygen, that if prolonged, can cause damage or death. Occurs in childbirth due to contractions, which slows the fetal heart rate
29Home births
More often occur in the least affluent nations, can be dangerous unless a trained birth attendent is present
30Hospital births
Most common in affluent nations, one other family member can witness the birth, and a doula may be present to support the person in labor
31Doula
A person who helps with the birth process. Currently, they are likely to arrive at the birthing parent's home during early labor and later work alongside a hospital's staff
32Newborns
Usually cry spontaneously, color changes from bluish to redish, and eyes open, fingers grab, and toes stretch
33Apgar scale
Quick assessment of the newborn's heart rate, breathing, muscle tone, color, and reflexes. Completed 1 and 5 minutes after birth. Scores are from 0-2 for each category, where 7+ is desired
34Cesarean sections (c-sections)
A surgical birth in which incisions through the abdomen and uterus allow the fetus to be removed quickly instead of through the vagina. Medically indicated for 10-15% of births and adds risk for maternal death
35Advantages of a c-section
For hospitals: easier to schedule, quicker, and more expensive; for birthing parents: advance planning, quick birth
36Disadvantages of a c-section
Breastfeeding is less common, medical complications are more likely, babies are more likely to develop asthma, diabetes, and obesity, and they miss out on the beneficaial microbiome from the birth canal
37Drugs in the birth process
International variations in drugs to reduce pain or start or speed labor. Many developed nations prescribe opioids, and over half of US births include an epidural
38Teratogen
An agent or condition, including viruses, drugs, and chemicals, that can impair prenatal development and result in birth defects or even death. Some only cause damage during a critical period
39Threshold effect
In prenatal development, when a teratogen is relatively harmless in small doses but becomes harmful once exposure reaches a certain level. Thresholds are controversial
40Fetal alcohol syndrome (FAS)
A cluster of birth defects, including atypical facial characteristics, slow physical growth, and reduced intellectual ability, that may occur in the fetus of someone who drinks alcohol while pregnant
41Genetic vulnerability
Genes of both the carrier and the fetus interact with teratogens
42Example of genetic susceptibility
Male fetuses are more often spontaneously aborted, stillborn, or harmed than are female fetuses, and one maternal allele reduces folic acid that can produce neural-tube defects (spina bifida or anencephaly); more common in certain ethnic groups
43Unregulated and potentially harmful substances
Some herbal products, over-the-counter drugs, nutritional supplements
44Common substances (drugs and pesticides)
Cigarettes, alcohol, marijuana, opioids
45COVID-19 vaccines
Complications, including stillborn infants, were twice as high for the unvaccinated compared to the vaccinated
46Low birthweight (LBW)
Less than 2,500 grams (5.5 pounds) at birth
47Very low birthweight (VLBW)
Under 1,500 grams (3 pounds, 5 ounces) at birth
48Extremely low birthrate
Under 1,000 grams (2 pounds, 3 ounces) at birth
49Preterm birth
occurs at 35 or fewer weeks after conception, associated with LBW
50Small for gestational age (SGA)
A newborn whose birthweight is significantly lower than expected, given the time since conception
51Causes of preterm birth
Malnutrition, drug use, multiple births
52Consequences of LBW
Developmental delays, cognitive, visual, and hearing impairments, behavioral difficulties, higher rates of diabetes, obesity, heart disease, and depression
53Couvade syndrome
Symptoms of pregnancy and birth experienced by partners of pregnant parents
54Other factors for low birthweight
Unintended pregnancies increase the incidence of this and birth defects, and partners' attitudes. Partner involvement is important in the overall health of the pregnancy
55Immigrant paradox
The surprising, paradoxical fact that low-SES immigrant birthing parents tend to have fewer birth complications than native-born peers with higher incomes
56Explanation for immigrant paradox
One hypothesis is that immigrants are particularly likely to support their relatives who are pregnant, keeping them healthy and buffering poverty stress
57Internation comparision (LBW)
Low birthweight is less common in most nations than is was, but it is increasing in some nations, the US among them
58Hypothesis for why US birthweights are low
Food insecurity or increased substance use
59Reflex
An unlearned, involuntary action or movement in response to a stimulus, occurs without conscious thought
60Newborn's 3 sets of reflexes (protection)
Maintaining oxygen, maintaining constant body temp, and managing feeding
61Newborn's other reflexes (signify state of brainody functions)
Babinski, stepping, swimming, palmar grasping, and moro reflex
62Postpartum depression
A new parent's feelings of inadequacy and sadness in the days and weeks after giving birth
63Postpartum depression facts
Rates range from 5-27%, some causes may predate pregnancy, others correlate during pregnancy or birth process, baby care is complex, baby may be disappointing, initial euphoria may be followed by anxiety and depression, breastfeeding and social support may help
64Birthing parents: partners
Support from a well-functioning, supportive family may meet the baby's social needs, but partners are also vulnerable to depression and may experience hormonal changes, sleep difficulties, and new parent stress
65Parent-infant bond
The strong, loving connection that forms as parents hold, examine, and feed their newborn, immediate contact is not essential for human bonding
66Kangaroo care
A form of newborn care in which parents rest their babies on their naked chests, like kangaroo mothers