LAB 9

Contain a carboxyl group: -CO2

It must be the terminal group on a chain

Acid derivatives replace the –OH (hydroxyl)
group with another functional group:
(NH2 ), esters (-OR), acyl halides (-X),
anhydrides (-CO2 R).

(-OR)

(-X)

(-CO2 R)

High BP & MP, higher than equivalent weight alcohols

Ka & pKa: the low pKa of acids compared to
alcohols is due to resonance stabilization of the
conjugate base, i.e.

These are used to suppress signs and
symptoms of inflammation including pain

All are weak organic acids except

Acetyl Salicylic Acid, Diclofenac,
Ibuprofen, Mefenamic Acid, Tolmetin,
Nabumetone

Anti-seizure drug

– Antidote for heavy
metal poisoning

Present in Vinegar

A prostaglandin, a small amount of _____ lowers blood pressure significantly