1Carbamazepine
Therapeutic Drug level
4-12 mcg/ml
Digoxin
2Therapeutic Drug level
4-12 mcg/ml
3Digoxin
Therapeutic Drug level
Afib:(0.8-2ng/ml)
HF: (0.5-0.9ng/ml)
4Gentamicin (traditional dosing)
Therapeutic Drug level
Peak: 5-10 mcg/ml
Trough: <2 mcg/ml
5Lithium
Therapeutic Drug level
0.6 -1.2 mEq/L
6Phenytoin/Fosphenytoin
Therapeutic Drug level
10-20 mcg/ml
*correct for albumin*
7Free Phenytoin
Therapeutic Drug level
1-2.5 mcg/ml
8A) Procainamide
B) NAPA
C) Combined
Therapeutic Drug level
5-15 mcg/ml
Tobramycin (traditional dosing)
9Therapeutic Drug level
5-15 mcg/ml
10Tobramycin (traditional dosing)
Therapeutic Drug level
Peak: 5-10mcg/ml
Trough <2 mcg/ml
11Valproic Acid
Therapeutic Drug level
50-100 mcg/ml
*correct for albumin*
12Vancomycin
Therapeutic Drug level
Trough: 15-20 mcg/ml serious infxs
Trough:10-15 mcg/ml less serious infxns
13Warfarin
Therapeutic Drug level
LATIN
Lorazepam
Amiodarone
Tacrolimus
Taxanes
Insulin
Nitroglycerin
"Leach Absorbs To Take In Nutrients"
14Lorazepam
A) PVC incompatible
B) Requires Filter for Administration
15Amiodarone
A) PVC incompatible
B) Requires Filter for Administration
C) Can cause Optic Neuropathy
D) Can cause Pulmonary FIbrosis
E) Can cause Hypothyroidism
F) A) Can cause Hyperthyroidism
16Tacrolimus
A) PVC incompatible
B)Causes Kidney Disease
C) Raise K levels
D) raise LDL and TG
E)Can increase QT interval
F) Can raise Blood Glucose
G) Can Increase Uric Acid
17Taxanes
A) PVC incompatible
A) Requires Filter 4 Admin (except doce)
18Insulin
A) PVC incompatiblen
19Nitroglycerin
A) PVC incompatible
20Drugs only compatible with Saline (No Dextrose)
"A DIAbetic Can't Eat Pie"
Ampicillin
Daptomycin
Infliximab (Remicade)
Amp/Sulbactam
Caspofungin (Cancidas)
Ertapenem (Invanz)
Phenytoin (Dilantin)
21Ampicillin
A) Saline only
22Daptomycin
A) Saline only
23Infliximab (Remicade)
A) Saline only
24Amp/Sulbactam
A) Saline only
25Caspofungin
A) Saline only
26Ertapenem
A) Saline only
27Phenytoin
A) Saline only
B) Requires Filter for Administration
C) Do not refrigerate
28Dextrose compatible Only (No Saline)
"Obese Baker Avoids Salt"
Oxaliplatin
SMX/TMP (Bactrim)
Amphotericin B
Quinupristin/Dalfopristin (Synercid)
29Oxaliplatin
A) Dextrose only
30SMX/TMP
A) Dextrose only
B) Do not refrigerate
C) Raise K levels
31Amphotericin B
A) Dextrose only
B) Requires Filter for Administration
C)Causes Kidney Disease
32Quinupristin/Dalfopristin
"Synercid"
A) Dextrose only
33Drugs with Filter Requirements
GAL PLAT whose head is flat
Golimumab
Amiodarone
Lorazepam
Phenytoin
Lipids
Amphotericin B
Taxanes (except docetaxel )
34Golimumab
A) Requires Filter for Administration
35Lipids
A) Requires Filter for Admin (1.2micron)
B) raise TGs only
36Do Not Refrigerate
"Dear Sweet Pharmacist, Freezing Makes Me Edgy"
Dexmedetomidine(Precedex)
SMX/TMP
Phenytoin
Furosemide
Metronidazole
Moxifloxacin(Avelox)
Enoxaparin(Lovenox)
37dexmedetomidine
A) Do not refrigerate
38Furosemide
A) Do not refrigerate
B)Causes Kidney Disease
39Metronidazole
A) Do not refrigerate
B) NO renal adjustment needed
40Moxifloxacin
A) Do not refrigerate
41Enoxaparin
A) Do not refrigerate
B)Dose/Interval change in CKD
42Protect from Light during Administration
"Protect Every Necessary Med from Daylight"
Phytonadione (VitK)
Epoprostenol (Flolan)
Nitroprusside
Micafungin
Doxycycline
43Phytonadione
A) Protect from light w/ administration
44Epoprostenol
A) Protect from light w/ administration
45Nitroprusside
A) Protect from light w/ administration
46Micafungin
A) Protect from light w/ administration
47Doxycycline
A) Protect from light w/ administration
B) NO renal adjustment needed
48Hazardous Non-Antineoplastic Drugs
Chloramphenicol
Telavancin
Warfarin
Flu/Voriconazole
ABC/entecavir/Nevirapine/ZDV
CIdofocir/Gan/Valganciclovir
Isotretinoin
Dronedarone
Acitretin, Leflunomide, Teriflunomide
Dutasteride, Finasteride
Estrogens
Paroxetine
Exenatide
Lomitapide
Clobazam,clonazepam
Carbamazepine, oxcapraz, divalproex, fos/phenytoin,Topiramate, Vigabatrin, Zonisamide
Colchicine
Ivabradine
Ribavirin
Pamidronate, Zoledronic Acid
Methimazole, Propylthiouracil
Temazepam, Triazolam
Dihydroergotamine
Fingolimod, INF-β-1b
Apomorphine, Rasagiline
Ambrisentan, Bosentan, Macitentan, Riociguat
Darbepoetin alfa
Ziprasione
Azathioprine, Cyclosporine, Mycophenolate, Tacrolimus, Sirolimus
49Drugs that cause Kidney DIsease
Aminoglycosides,
Amphotericin-B,
Cisplatin
Cyclosporine,
Loop diuretics,
NSAIDs,
Radiographic contrast dye,
Tacrolimus
Vancomycin
50Aminoglycosides
"Genta, Neomycin, Streptomycin"
A)Cause Kidney Disease
B)Dose/Interval change in CKD
51Cisplatin
A)Causes Kidney Disease
52Cyclosporine
A)Causes Kidney Disease
B) Raise K levels
C) raise LDL and TG
D) Can raise Blood Pressure
E) Can raise Blood Glucose
F) Can Increase Uric Acid
53Loop DIuretics
A)Causes Kidney Disease
B) can inc Uric Acid
54NSAIDs
A)Causes Kidney Disease
B) CI'd w/ CrCl <30
C) Can raise Blood Pressure
D) Can worsen HF
E) Teratogenic
F) Can worsen GERD
55Radiographic Contrast Dye
A)Causes Kidney Disease
56Vancomycin
A)Causes Kidney Disease
B)Dose/Interval change in CKD
57Drugs that require Inc Interval or Dec Dose in CKD
Aminoglycosides
B lactams
Fluconazole
Quinolones (except moxifloxacin)
Vancomycin
Enoxaparin
Rivaroxaban (Afib)
H2RAs
Metoclopramide
Bisphosphanates
Lithium
58Β-Lactams
A)Dose/Interval change in CKD
59Fluconazole
A)Dose/Interval change in CKD
60Qunolones
A)Dose/Interval change in CKD
----Except Moxi
61Rivaroxaban
A)Dose/Interval change in CKD
B) CI'd w/ CrCl <30 (DVT/PE)
62H2RAs
A)Dose/Interval change in CKD
63Metoclopramide
A)Dose/Interval change in CKD
64Bisphosphonates
A)Dose/Interval change in CKD
65Lithium
A)Dose/Interval change in CKD
B) Can cause Hypothyroidism
C) Teratogenic
D) Can cause weight gain
E) Can Lower seizure threshold
66Drugs CI'd in CrCl <60
Nitrofurantoin
67Nitrofurantoin
A) CI'd w/ CrCl<60
68Drugs CI'd in CrCl <50
TDF (Stribild, Complera, Atripla, Symfi)
Voriconazole IV
69TDF
A) CI'd in CrCl <50
B) BBW! for Liver Damage
70Voriconazole IV
A) CI'd in CrCl <50 (due to vehicle)
71Drugs CI'd in CrCl <30
TAF (Genvoya, Biktarvy, Descovy, Odefesey, Symtuza)
NSAIDs
Dabigatran (DVT/PE)
Rivaroxaban (DVT/PE)
72TAF
A) CI'd w/ CrCl <30
B) BBW! for Liver Damage
73Dabigatran
A) CI'd w/ CrCl <30 (DVT/PE)
B) can worsen GERD
74Drugs CI'd w/ GFR <30
SGLT2 inhibitors
Metformin
75SGLT2 inhibitors
A) CI'd w/ GFR <30
B) raise LDL only
C) Can cause weight loss
76Metformin
A) CI'd w/ GFR <30
77Drugs that raise potassium levels
ACE inhibitors
Aldosterone rec. antagonists
Aliskiren
ARBs
Canagliflozin
Drospirenone
SMX/TMP
Cyclosporine
Everolimus
Tacrolimus
78ACE inhibitors
A) Raise K levels
79Aldosterone receptor Antagonists
A) Raise K levels
80Aliskiren
A) Raise K levels
82Canagliflozin
A)CI'd w/ GFR <30
B) Raise K levels
83Drospirenone
A) Raise K levels
84Everolimus
A) Raise K levels
85Drugs with BBW for liver damage
Acetaminophen
Isoniazid
Ketoconazole(PO)
Methotrexate
Nefazodone
Nevirapine
NRTIs
Propylthiouracil
Tipranavir
Valproic Acid
86Acetaminophen
A) BBW! for Liver Damage
87Isoniazid
A) BBW! for Liver Damage
B) DILE
88Ketoconazole
A) BBW! for Liver Damage
89Methotrexate
A) BBW! for Liver Damage
B) Can Cause Pulmonary Fibrosis
C) Teratogenic
90Nefazodone
A) BBW! for Liver Damage
91Nevirapine
A) BBW! for Liver Damage
92NRTIs
A) BBW! for Liver Damage
93Propylthiouracil
A) BBW! for Liver Damage
B) DILE
94Tipranavir
A) BBW! for Liver Damage
95Valproic Acid
A) BBW! for Liver Damage
B) Can cause Hemolytic Anemia
C) Teratogenic
D) Can cause Weight Gain
96Hep A vaccine
Havrix, Vaqta (Inactivated)
97Hep B vaccine
Engerix-B, Recombivax HB (inactivated)
98Hep A/B vaccine
Twinrix (Inactivated)
99Japanese encephalitis vaccine
Ixiaro (inactivated)
100Meningococcus vaccine
Menactra, Menveo (inactivated)
101Polio Vaccine
IPOL (Inactivated)
102Typhoid Vaccine
IM- Inactivated(Typhim Vi)
PO- Live (Vivotif)
103Cholera vaccine
Vaxchora (live) PO
104Yellow Fever vaccine
YF-VAX Live
105Antibiotics with NO renal dose adjustments needed
Dicloxacillin
Nafcillin
Ceftriaxone
Clindamycin
Doxycycline
Azithromycin
Erythromycin
Metronidazole
LInezolid
106Antistaphylococcal Penicillins
A) NO renal adjustment needed
107Ceftriaxone
A) NO renal adjustment needed
108Clindamycin
A) NO renal adjustment needed
109Azithromycin
A) NO renal adjustment needed
110Erythromycin
A) NO renal adjustment needed
111Linezolid
A) NO renal adjustment needed
B) Optic Neuropathy risk
C) Can lower BG
112STRs for HIV
INSTI Based
- Stribild
- Genvoya
- Biktarvy
- Triumeq
NNRTI based
- Atripla
- Complera
-Odefsey
PI Based
- Symtuza
113EVG/COBI/FTC/TDF
Stribild - INSTI STR
114EVG/cobi/FTC/TAF
Genvoya - INSTI STR
115Bictegravir/FTC?TAF
Biktarvy - INSTI STR
116DTG/ABC/3TC
Triumeq - INSTI STR
117EFV/FTC/TDF
Atripla - NNRTI STR
118RPV/FTC/TDF
Complera -NNRTI STR
119RPV/FTC?TAF
Odefsey -NNRTI STR
120DRV/cobi/FTC/TAF
Symtuza- PI STR
121Drugs that raise LDL and TG
PIs
Steroids
Diuretics
Cyclosporine
Tacrolimus
122Protease Inhibitors
A) raise LDL and TG
B) Can raise Blood Glucose
123Steroids
A) raise LDL and TG
B) Can raise Blood Pressure
C) Can raise Blood Glucose
124Diuretics
A) raise LDL and TG
B) Can raise Blood Glucose
C) Can worsen BPH
D) Can Increase Uric Acid
125Drugs that raise LDL only
Fibrates
SGLT2 Inh
126Fibrates
A) raise LDL only
127Drugs that raise TG only
IV lipids
Propofol
BBs
Atypical Antipsychotics
128Propofol
A) raise TGs only
129Β Blockers
A) raise TGs only
B) Can Lower Blood Glucose
C) Can Raise BLood GLucose
130Atypical Antipsychotics
A) raise TGs only
131Drugs that can raise Blood Pressure
Cyclosporine
NSAIDs
Steroids
132Key IV HTN meds for Hypertensive Crisis
Chlorothiazide
Clevidipine
Diltiazem
Enalaprilat
Esmolol
Hydralazine
Labetalol
Metoprolol tartrate
Nicardipine
Nitroglycerin
Nitroprusside
Propranolol
Verapamil
133Drugs that can worsen HF
Drug Information NATION
DPP4 inh
Immunosuppressants
NonDHP CCBs
Antiarrhythmics (Class I) -(procainamide, quinidine, flecainide)
Thiazolidinediones
Itraconazole
Oncology meds (doxorubicin/daunorubicin)
NSAIDs
134Alogliptin
A) Can worsen HF
135Saxagliptin
A) Can worsen HF
136Immunosuppressants (etanerceptituximab)
A) Can worsen HF
137Diltiazem
A) Can worsen HF
138Verapamil
A) Can worsen HF
139Procainamide
A) Can worsen HF
B) DILE
140Flecainide
A) Can worsen HF
141quinidine
A) Can worsen HF
142Thiazolidinediones
"glitazones'
A) Can worsen HF
143Itraconazole
A) Can worsen HF
144Doxorubicin
A) Can worsen HF
145daunorubicin
A) Can worsen HF
146Drugs that can prolong QT interval
Class 1 and 3 Antiarrhythmics
Quinolones
Macrolides
All Azole antifungals (except isa)
TCAs(amitriptyline, clomipramine, doxepin)
SSRIs(citalopram)
SNRIs(mirtazapine, trazodone)
5HT3 antagonists(droperidol
Antipsychotics(chlorpromazine, clozapine, haloperidol, olanzapine, paliperidone, quetiapine, risperidone, ziprasidone
Donepezil,
fingolimod
methadone
tacrolimus
147Quinolones
A)Can increase QT interval
B) Can raise Blood Glucose
C) Can Lower Blood Glucose
D) Teratogenic
E) Can Lower seizure threshold
148Macrolides
A)Can increase QT interval
149Azole Antifungals
A)Can increase QT interval
150TCA's (Amitryptyline, doxepin, clomipramine)
A)Can increase QT interval
151SSRIs (citalopram)
A)Can increase QT interval
152SNRIs( mirtazapine, trazodone)
A)Can increase QT interval
153droperidol
A)Can increase QT interval
154Antipsychotics (Haldol, ziprasadone, quetiapine risperidone etc.)
A)Can increase QT interval
155Methadone
A)Can increase QT interval
156Donepezil
A)Can increase QT interval
157Drugs that can cause Hemolytic Anemia
Dapsone
Methylene Blue
Primaquine
Pegloticase
Rasburicase
Valproic Acid
158Dapsone
A) Can cause Hemolytic Anemia
159Methylene Blue
A) Can cause Hemolytic Anemia
160Primaquine
A) Can cause Hemolytic Anemia
161Pegloticase
A) Can cause Hemolytic Anemia
162Rasburicase
A) Can cause Hemolytic Anemia
163Key Vaccines in SIckle Cell Disease
Childhood
- Haemophilus Influenza B (HiB)
- PCV13/ Prevnar
Additional for asplenia
- Menactra/Menveo
- MenB:Bexsero/Trumenba
- PPSV23/ Pneumovax 23
- PCV13/Prevnar
164Drugs that increase IOP
Anticholinergics (oxybutynin,tolterodine,benztropine, TCAs)
antihistamines
scopolamine
Chronic steroids
Topiramate
165Oxybutynin
A) Can increase IOP
166Tolterodine
A) Can increase IOP
167Benztropine
A) Can increase IOP
168TCAs
A) Can increase IOP
169Scopolamine
A) Can increase IOP
170Chronic steroids, PredForte
A) Can increase IOP
171Topiramate
A) Can increase IOP
B) Teratogenic
C) Can cause weight Loss
172Drugs Known to Cause vision changes
Retinopathy
- Chloroquine/Hydroxychloroquine
Optic Neuropathy
- Amiodarone
- Ethambutol
- Linezolid
Floppy Iris syndrome
- Alpha blockers (Doxazosin)
Color discrimination
- Digoxin (yellowreen)
- PDE-5 inh ( vision loss)
- Isotretinoin (dec night vision)
-Vigabatrin (permanent vision loss)
Voriconazole( abnormal vision photophobia)
173Chloroquine
Retinopathy
- Chloroquine/Hydroxychloroquine
Optic Neuropathy
- Amiodarone
- Ethambutol
- Linezolid
Floppy Iris syndrome
- Alpha blockers (Doxazosin)
Color discrimination
- Digoxin (yellow / green)
- PDE-5 inh ( vision loss)
- Isotretinoin (dec night vision)
-Vigabatrin (permanent vision loss)
Voriconazole( abnormal vision photophobia)
174Hydroxychloroquine
A) can cause retinopathy
175Ethambutol
A) Can cause Optic Neuropathy
176Doxazosin
A) Floppy Iris Syndrome
177Digoxin
A) Yellowreen vision, halos
178PDE-5 inhibitors
A) Yellow / green vision, halos
179Voriconazole
A) color vision changes, photophobia
180Isotretinoin
A) dec. Night Vision
181Vigabatrin
A) permanent vision loss (HIGH RISK)
182Drugs that can cause Pulmonary Fibrosis
Amiodarone
Bleomycin
Dronedarone
Methotrexate
183Bleomycin
A) can cause pulmonary fibrosis
184Dronedarone
A) Can cause pulmonary Fibrosis
185Drugs that can raise blood sugar
Β Blockers
Diuretics
Cyclosporine, tacrolimus
Niacin
Protease inhibitors
Quinolones
Clozapine, olanzapine, quetiapine
Statins
Steroids
186Β blockers
A) Can raise Blood Glucose
187Niacin
A) Can raise Blood Glucose
B) Can Increase Uric Acid
188Clozapine
A) Can raise Blood Glucose
B) Can Lower seizure threshold
189Olanzapine
A) Can raise Blood Glucose
190Quetiapine
A) Can raise Blood Glucose
191Statins
A) Can raise Blood Glucose
192Drugs that can Lower Blood Glucose
Linezolid
Lorcaserin (Belviq)
Pentamidine
Β-Blockers
Quinolones
193Lorcaserin
A) Can Lower Blood Glucose
194Pentamidine
A) Can Lower Blood Glucose
195Drugs that can cause hypothyroidism
I TALC
Interferons
Tyrosine Kinase Inh(sunitinib)
Amiodarone
Lithium
Carbamazepine
*Hashimoto's DIsease
196Interferons
A) Can cause Hypothyroidism
B) Can worsen depression
197TKIs (sunitinib)
A) Can cause Hypothyroidism
198Carbamazapine
A) Can cause Hypothyroidism
199Drugs that can Cause DILE
"My Pretty Malar Marking Probably Has A TransIent Quality"
Methimazole
Propylthiouracil
Methyldopa
Minocycline
Procainamide
Hydralazine
AntiTNF agents
Terbinafine
Isoniazid
Quinidine
206Teratogenic drugs
Isotretinoin
Quinolones
Tetracyclines
Warfarin
Statins
ACEinh, ARBs, Aliskiren, ARNIs
Hormones
Dihydroergotamine/ ergotamine
Hydroxyurea
Lithium
Methotrexate
Misoprostol
NSAIDs
Paroxetine
Ribavirin
Thalidomide
Topiramate
Valproic Acid
207Tetracyclines
A) Teratogenic
B) Can worsen GERD
208Warfarin
A) Teratogenic
209Dihydroergotamine
A) Teratogenic
210Ergotamine
A) Teratogenic
211Hydroxyurea
A) Teratogenic
212Misoprostol
A) Teratogenic
213Paroxetine
A) Teratogenic
214Ribavirin
A) Teratogenic
215Thalidomide
A) Teratogenic
216Drugs that worsen BPH
Anticholinergics (Benztropine)
Antihistamines( diphenhyramine,chlorpheniramine)
Caffeine
Pseudoephedrine
Diuretics
SNRIs
TCAs
Testosterone
217Benztropine
A) Can worsen BPH
218diphenhydramine
A) Can worsen BPH
219Chlorpheniramine
A) Can worsen BPH
220Caffeine
A) Can worsen BPH
221Pseudoephedrine
A) Can worsen BPH
222SNRIs
A) Can worsen BPH
223Testosterone
A) Can worsen BPH
224Drugs that can cause weight gain
Antipsychotics
Insulin, Meglitinies, SUs, TZDs
Valproic Acid
Lithium
Mirtazapine
Steroids
225Mirtazapine
A) Can cause weight gain
226Drugs that can cause weight loss
GLP1 agonists (exenatide,liraglutide)
SGLT2 inhib
pramlintide
Topiramate
227GLP-1 agonists
A) Can cause weight loss
228Pramlintide
A) Can cause weight loss
229Drugs that increase Uric Acid
Aspirin
Diuretics
Niacin
Pyrazinamide
Tacrolimus
Cyclosporine
230Aspirin
A) Can increase Uric Acid (Lower Doses)
B) Can worsen GERD
231Pyrazinamie
A) Can Increase Uric Acid
232Drugs that can worsen depression
Atomoxetine
Indomethacin
Efavirenz
Rilpivirine
BBs (propranolol)
Interferons
Varenicline
233Atomoxetine
A) Can worsen depression
234Indomethacin
A) Can worsen depression
235Efavirenz
A) Can worsen depression
236Rilpivirine
A) Can worsen depression
237Propranolol
A) Can worsen depression
238Varenicline
A) Can worsen depression
B) Can worsen Insomnia
C) Can Lower seizure threshold
239Drugs that can cause anxiety
Albuterol
aripiprazole
haloperidol
Buproprion
Levothyroxine
Theophylline
240Albuterol
A) Can cause anxiety
241Aripiprazole
A) Can cause anxiety
242Haloperidol
A) Can cause anxiety
243Buproprion
A) Can cause anxiety
B) Can worsen insomnia
C) Can Lower seizure threshold
244Theophylline
A) Can cause anxiety
B) Can Lower seizure threshold
245Levothyroxine
A) Can cause anxiety
246Drugs that can worsen insomnia
Buproprion
Fluoxetine
Varenicline
247Fluoxetine
A) Can worsen Insomnia
248Drugs that can Lower Seizure Threshold
Buproprion
Clozapine
Theophylline
Varenicline
Carbapenems
Lithium
Meperidine
Penicillin
Quinolones
Tramadol
249Carbapenems
A) Can Lower seizure threshold
250Meperidine
A) Can Lower seizure threshold
251Penicillins
A) Can Lower seizure threshold
252Tramadol
A) Can Lower seizure threshold
253Drugs that worsen GERD
Aspirin
NSAIDs
Bisphosphonates
Dabigatran
Estrogen products
Fish Oil
Iron
Steroids
Tetracyclines
254Iron supplements
A) Can worsen GERD
255Drugs that are constipating
aluminum antacids,
anticholinergics,
non-dhp CCB (esp Verapamil)
, bismuth,
clonidine,
iron,
colesevelam.
opioids,
sucralfate
256Drugs that can cause diarrhea
antibiotics,
antacids containing magnesium, colchicine,
metoclopramide,
misoprostol,
quinidine
257Drugs associated with photosensitivity
Amiodarone
Diuretics
MTX
Retinoids
Quinolones
St. Johns Wart
Sulfa ATBs
Tacrolimus
Tetracyclines
Voriconazole
258Drugs associated with TTP
Clopidogrel
Sulfamethoxazole
259drugs associated with severe skin reactions
Abacavir
Allopurinol
Carbamazepine
Ethosuximide
Lamotrigine
Modafinil
Penicillins
Phenytoin
Sulfamethoxazole