1infectious disease caused by the most recent discovered coronavirus
COVID-19
2large family of viruses which can cause illness in animals or huma
coronavirus
3COVID-19
Causative Agent:
SARS-CoV-2
4discovered in january 2020 to be a novel betacoronavirus of the same subgenous as SARS-CoV
SARS-CoV-2
6when droplet particles are >5-10um in diameter
respiratory droplets
7when there are <5um in diameter
droplet nuclei
8covid-19 most common symptoms
fever
dry cough
tiredness
9covid-19 less common symptoms
aches and pains
sore throat
diarrhea
conjunctivitis
headache
loss of taste and smell
rask on skin, discoloration of fingers or toes
10covid-19 serious symptoms
DOB or shortness of breath
chest pain or pressure
loss of speech or movement
11covid-19 diagnostic test
nucleic acid amplification test (NAAT) such as RT-PCR
12it detects the presence of virus and sensitivity is higher and more accurate the RDT
RDT
13the sensitivity of these test might be expected to vary from 34% to 80%
it detects covid-19 antibodies (lgG and lgM)
Rapid Diagnostic Test (RDT)
14zoonotic disease (spread from animals to people) that can cause severe respiratory illness
first identified in saudi 2012
MERS-CoV (Middle East Respiratory Syndrome)
15MERS-CoV
Causative Agent:
MIDDLE EAST RESPIRATORY SYNDROME (MERS)
16MERS-CoV
Clinical Manifestations:
fever
rhinorrhea, mostly clear
pulmonary findings
hypotension
17use of CDC's 2012 realtime reverse transcriptase-PCR aasay to test for MERS-CoV in clinical respiratory, serum, stool specimen
rRT-PCR assay
18MERS-CoV
assessment and diagnostic findings
serology
rRT-PCR assay
laboratory studies
imaging studies
19viral respiratory disease caused by a SARS-associated coronavirus
first identified at the end of february 2003
SARS (Severe Acute Respiratory Syndrome)
20first case of SARS in the Philippines
april 11, 2003
21SARS
causative agent
SARS-associated coronavirus (SARS-CoV)
22SARS
incubation period
symptoms appeared 2-7days or 10
23SARS
MOT:
airborne
direct contact w mucous membrane
indirect through infected fomites
causal or social contact
contamination of inanimate materials