1What is the main function of the nervous system?
To detect and respond to external or internal changes in the body, voluntarily or involuntarily.
2What are the three basic stages of nervous system function?
Sensory input, integration, and motor output.
3What is sensory input?
The detection of stimuli by sensory receptors.
4What is integration?
The processing and interpretation of incoming signals.
5What is motor output?
The transmission of signals that produce a response.
6What are the two main divisions of the nervous system?
The central nervous system (CNS) and the peripheral nervous system (PNS).
7What structures make up the central nervous system (CNS)?
The brain and spinal cord.
8What is the main function of the CNS?
To receive, interpret, and integrate signals and coordinate responses.
9What is the main function of the peripheral nervous system (PNS)?
To carry sensory information to the CNS and motor commands from the CNS to effectors.
10What structures are included in the PNS?
Cranial nerves and spinal nerves.
11What is the general flow of information through the nervous system?
PNS → CNS → PNS.
12What is the afferent sensory division?
The division of the nervous system that carries sensory information toward the CNS.
13What does afferent mean?
Carrying signals toward the CNS.
14What is the efferent motor division?
The division that carries motor commands from the CNS to effectors.
15What does efferent mean?
Carrying signals away from the CNS toward the periphery.
16What is an interneuron?
A neuron located exclusively in the CNS that receives, integrates, and relays information between sensory and motor neurons.
17What is the basic sequence of a nervous system response?
The afferent division carries information to the CNS, the CNS integrates the signal, and the efferent division carries the response to effectors.
18Where do cranial nerves originate?
From the brain; many are associated with the brainstem.
19What does somatic mean in the nervous system?
Related to the external body, including the skin, skeletal muscles, and bones.
20What does visceral mean?
Related to internal organs, such as digestive organs, the bladder, heart, and lungs.
21What are the two main divisions responsible for autonomic responses?
The sympathetic and parasympathetic divisions.
22What is the general function of the autonomic nervous system?
To regulate involuntary functions of internal organs and structures.
23What response is associated with the sympathetic division?
Fight or flight.
24What response is associated with the parasympathetic division?
Rest and digest.
25What do sensory receptors detect?
Information from inside the body or the external environment.
26How does sensory information reach the CNS?
Through afferent, or sensory, nerves.
27What can the spinal cord do with sensory information?
Relay it to the brain or integrate it locally to produce a spinal reflex.
28What is the function of specialized regions of the brain?
To process and integrate sensory information and determine how to respond.
29How do motor commands reach effectors from the brain?
Through the spinal cord and peripheral nerves, or through cranial nerves.
30What are effectors?
Muscles, organs, or glands that carry out a response.
31What is an exteroceptor?
A receptor that detects stimuli from outside the body.
32What stimuli can exteroceptors detect?
Touch, pressure, pain, temperature, smell, hearing, taste, and vision.
33What is an interoceptor or visceroceptor?
A receptor that detects stimuli originating from internal organs and viscera.
34What changes can interoceptors detect?
Chemical changes, tissue stretching, and changes such as blood pressure.
35What is a proprioceptor?
A receptor that detects stretching in muscles, joints, tendons, and ligaments.
36What information do proprioceptors provide to the CNS?
Information about body position and movement.
37What are the two criteria used to functionally classify sensory receptors?
The location of the receptor and the type of stimulus it detects.
38What are mechanoreceptors?
Receptors that detect mechanical forces, such as touch, pressure, stretching, and vibration.
39What do baroreceptors detect?
Changes in pressure, especially blood pressure.
40What type of receptors are proprioceptors?
Mechanoreceptors.
41What do thermoreceptors detect?
Changes in temperature.
42What do chemoreceptors detect?
Chemical changes, such as changes in blood composition.
43What do photoreceptors detect?
Light.
44What do nociceptors detect?
Stimuli associated with pain.
45What are the three main structural categories of sensory receptors?
Free nerve endings, encapsulated nerve endings, and specialized receptor cells.
46What are free nerve endings?
Unencapsulated dendritic endings that mainly detect pain and temperature, while some detect light touch.
47Where are free nerve endings especially abundant?
In epithelia and the underlying connective tissue.
48What do free nerve endings mainly detect?
Pain and temperature; some also detect light touch.
49What are encapsulated nerve endings?
Dendritic endings surrounded by connective tissue that receive sensory stimuli.
50How does the capsule of an encapsulated nerve ending help it function?
It modifies sensitivity to stimuli and helps filter mechanical signals.
51What do tactile (Meissner's) corpuscles detect?
Light touch.
52Where are Meissner's corpuscles located?
In the papillary dermis.
53What do lamellar (Pacinian) corpuscles detect?
Pressure, especially deep pressure and vibration.
54Where are Pacinian corpuscles located?
In the reticular dermis and deeper tissues.
55What do bulbous corpuscles detect?
Stretching.
56Where can bulbous corpuscles be found?
In joint capsules and the dermis.
57What are specialized receptor cells?
Cells with specialized structures that detect specific stimuli.
58Which specialized cells detect light in the retina?
Photoreceptors, including rods and cones.
59What do the chemoreceptors in the carotid bodies detect?
Changes in the chemical composition of blood.
60Where do carotid body chemoreceptors send signals?
To the cardiorespiratory centers in the medulla oblongata.
61What blood changes stimulate carotid body chemoreceptors?
Decreased pH and oxygen levels, and increased carbon dioxide levels.
62What response can stimulation of the carotid bodies produce?
An increase in breathing rate.
63How is a peripheral sensory receptor fully classified?
By combining its functional classification with its structural classification.
64How is a skin receptor that detects temperature classified?
As an exteroceptor, a thermoreceptor, and a free nerve ending.
65How are receptors that detect oxygen and carbon dioxide in the blood classified?
As interoceptors, chemoreceptors, and specialized receptor cells.
66How are receptors that detect muscle stretching classified?
As proprioceptors and mechanoreceptors; many are encapsulated nerve endings.
67How are rods and cones in the retina classified?
As specialized photoreceptor cells and exteroceptors.
68What are the two main types of cells in nervous tissue?
Neurons and neuroglia.
69What distinguishes neurons from other nervous tissue cells?
They are excitable cells that generate and transmit nerve signals.
70What is an action potential?
An electrical signal that propagates along a neuron's membrane.
71What is neuroglia?
A group of non-neuronal support cells that help protect, support, and insulate nervous tissue.
72Approximately how many neurons are in the average human brain?
About 86 billion.
73What are the metabolic characteristics of neurons?
They have high glucose and oxygen requirements.
74Do mature neurons normally divide?
No, mature neurons generally do not divide.
75What is the soma of a neuron?
The cell body of the neuron.
76What is the function of dendrites?
To receive signals and conduct them toward the cell body.
77What is the axon hillock?
The region where the axon originates from the cell body and where an action potential usually begins.
78What are axon terminals?
The endings of an axon that transmit signals to other cells.
79What do vesicles in axon terminals contain?
Neurotransmitters.
80What is chromatophilic substance?
Clusters of rough endoplasmic reticulum involved in protein synthesis.
81What is the function of Schwann cells?
To wrap around PNS axons and form myelin sheaths around many of them.
82What are nodes of Ranvier?
Gaps in the myelin sheath between adjacent myelinated segments.
83What is the function of nodes of Ranvier in nerve conduction?
They allow saltatory conduction, in which the action potential is regenerated from node to node.
84What are oligodendrocytes?
Glial cells in the CNS that form myelin sheaths around axons.
85What is the sequence of signal transmission through a neuron?
Dendrites → cell body → axon → axon terminals → target cell.
86How are neurons structurally classified?
According to the number of processes extending from the cell body.
87How are neurons functionally classified?
According to the direction and function of their nerve impulses.
88What structural type of neuron is common among sensory afferent neurons?
Unipolar or pseudounipolar.
89What structural type of neuron is common among motor efferent neurons?
Multipolar.
90What structural type of neuron is common among interneurons?
Multipolar.
91What are the three main structural types of neurons?
Multipolar, bipolar, and unipolar.
92What is a synapse?
The site where a nerve signal is transmitted between a neuron and another cell.
93Between what types of cells can synapses form?
Between two neurons or between a neuron and a muscle or gland cell.
94What is a presynaptic cell?
The cell that transmits the signal toward the synapse.
95What is a postsynaptic cell?
The cell that receives the signal across the synapse.
96What are the general functions of neuroglia?
Support, protection, insulation of nerve fibers, and maintenance of the neuronal environment.
97What are the four main types of neuroglia in the CNS?
Astrocytes, microglia, ependymal cells, and oligodendrocytes.
98What are the two main types of neuroglia in the PNS?
Satellite cells and Schwann cells.
99What are astrocytes?
The most abundant glial cells in the CNS, with processes that contact neurons and capillaries.
100What is the role of astrocytes in the blood-brain barrier?
They help maintain the barrier that restricts the movement of many substances from the blood into brain tissue.
101What is the blood-brain barrier (BBB)?
A selective barrier that limits the passage of substances from the blood into brain tissue.
102What substances can cross the blood-brain barrier under normal conditions?
Water, glucose, ions, and amino acids can cross through selective mechanisms.
103What other functions do astrocytes perform?
They regulate neurotransmitters and extracellular ions, help regulate blood flow, and respond to tissue damage.
104What are microglia?
Resident immune cells of the CNS that perform phagocytosis and defense.
105What is the main function of microglia?
To remove cellular debris and harmful agents through phagocytosis.
106What are ependymal cells?
Cells that line the brain's ventricles and the central canal of the spinal cord.
107What is the function of ependymal cells?
They participate in cerebrospinal fluid production and circulation and form a lining between the fluid and nervous tissue.
108What are oligodendrocytes?
Glial cells in the CNS that wrap around axons and form myelin.
109What is the function of satellite cells?
They surround neuronal cell bodies in the PNS and regulate their local environment.
110What is the function of Schwann cells in the PNS?
They surround axons and form myelin around many of them.
111What is the myelin sheath?
A lipid- and protein-rich covering that electrically insulates certain axons.
112How does myelin affect nerve conduction?
It reduces current leakage and increases the speed of nerve impulse conduction.
113What is a nerve?
A bundle of axons located in the PNS.
114What is a nerve tract?
A bundle of axons traveling together within the CNS.
115What is a collection of neuronal cell bodies called in the PNS?
A ganglion; plural, ganglia.
116What is a collection of neuronal cell bodies called in the CNS?
A nucleus; plural, nuclei.
117What are ascending tracts?
CNS tracts that carry information toward higher regions, such as the brain.
118What are descending tracts?
CNS tracts that carry signals from the brain toward lower regions, such as the spinal cord.
119What is white matter in the CNS?
A region consisting mainly of axons, many of which are myelinated, and neuroglia.
120What structures are mainly found in white matter?
Nerve tracts.
121What is gray matter in the CNS?
A region containing mainly neuronal cell bodies, dendrites, synapses, and neuroglia, along with unmyelinated axons.
122What structures are organized into groups in the gray matter of the CNS?
Neuronal nuclei, among other structures.
123Where do many CNS synapses occur?
In the gray matter.
124What is neuronal integration?
The processing of nervous system information that allows sensory input to be converted into motor output.
125What is a reflex?
A rapid, automatic motor response to a sensory stimulus.
126What is a reflex arc?
The neural circuit that produces a reflex response.
127Where is a simple spinal reflex integrated?
In the spinal cord, without waiting for the brain to process the signal.
128What is a monosynaptic reflex?
A reflex whose basic circuit contains one synapse and no interneurons.
129What is an example of a monosynaptic reflex?
The patellar reflex, or knee-jerk stretch reflex.
130What is a polysynaptic reflex?
A reflex that contains two or more synapses and one or more interneurons.
131What is an example of a polysynaptic reflex?
The withdrawal reflex that moves the hand away from a hot object.
132What is serial processing?
The processing of information through a sequence of steps.
133What is parallel processing in the nervous system?
The simultaneous processing of information by different neural pathways.
134What happens first when you touch a hot object?
A withdrawal reflex is activated, allowing the hand to move away quickly.
135Which pathway carries pain information from the spinal cord to the brain?
An ascending tract, such as the spinothalamic tract.
136What happens when the brain consciously processes pain?
It integrates sensory information and can generate motor commands to modify the response.
137How can the brain produce a voluntary movement?
Signals travel down motor tracts and activate efferent neurons that stimulate muscles.
138What is the main difference between a spinal reflex and a conscious motor response?
A reflex can be integrated rapidly in the spinal cord, while a conscious response requires processing in the brain