Chapter 12

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1
What is the main function of the nervous system?
To detect and respond to external or internal changes in the body, voluntarily or involuntarily.
2
What are the three basic stages of nervous system function?
Sensory input, integration, and motor output.
3
What is sensory input?
The detection of stimuli by sensory receptors.
4
What is integration?
The processing and interpretation of incoming signals.
5
What is motor output?
The transmission of signals that produce a response.
6
What are the two main divisions of the nervous system?
The central nervous system (CNS) and the peripheral nervous system (PNS).
7
What structures make up the central nervous system (CNS)?
The brain and spinal cord.
8
What is the main function of the CNS?
To receive, interpret, and integrate signals and coordinate responses.
9
What is the main function of the peripheral nervous system (PNS)?
To carry sensory information to the CNS and motor commands from the CNS to effectors.
10
What structures are included in the PNS?
Cranial nerves and spinal nerves.
11
What is the general flow of information through the nervous system?
PNS → CNS → PNS.
12
What is the afferent sensory division?
The division of the nervous system that carries sensory information toward the CNS.
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What does afferent mean?
Carrying signals toward the CNS.
14
What is the efferent motor division?
The division that carries motor commands from the CNS to effectors.
15
What does efferent mean?
Carrying signals away from the CNS toward the periphery.
16
What is an interneuron?
A neuron located exclusively in the CNS that receives, integrates, and relays information between sensory and motor neurons.
17
What is the basic sequence of a nervous system response?
The afferent division carries information to the CNS, the CNS integrates the signal, and the efferent division carries the response to effectors.
18
Where do cranial nerves originate?
From the brain; many are associated with the brainstem.
19
What does somatic mean in the nervous system?
Related to the external body, including the skin, skeletal muscles, and bones.
20
What does visceral mean?
Related to internal organs, such as digestive organs, the bladder, heart, and lungs.
21
What are the two main divisions responsible for autonomic responses?
The sympathetic and parasympathetic divisions.
22
What is the general function of the autonomic nervous system?
To regulate involuntary functions of internal organs and structures.
23
What response is associated with the sympathetic division?
Fight or flight.
24
What response is associated with the parasympathetic division?
Rest and digest.
25
What do sensory receptors detect?
Information from inside the body or the external environment.
26
How does sensory information reach the CNS?
Through afferent, or sensory, nerves.
27
What can the spinal cord do with sensory information?
Relay it to the brain or integrate it locally to produce a spinal reflex.
28
What is the function of specialized regions of the brain?
To process and integrate sensory information and determine how to respond.
29
How do motor commands reach effectors from the brain?
Through the spinal cord and peripheral nerves, or through cranial nerves.
30
What are effectors?
Muscles, organs, or glands that carry out a response.
31
What is an exteroceptor?
A receptor that detects stimuli from outside the body.
32
What stimuli can exteroceptors detect?
Touch, pressure, pain, temperature, smell, hearing, taste, and vision.
33
What is an interoceptor or visceroceptor?
A receptor that detects stimuli originating from internal organs and viscera.
34
What changes can interoceptors detect?
Chemical changes, tissue stretching, and changes such as blood pressure.
35
What is a proprioceptor?
A receptor that detects stretching in muscles, joints, tendons, and ligaments.
36
What information do proprioceptors provide to the CNS?
Information about body position and movement.
37
What are the two criteria used to functionally classify sensory receptors?
The location of the receptor and the type of stimulus it detects.
38
What are mechanoreceptors?
Receptors that detect mechanical forces, such as touch, pressure, stretching, and vibration.
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What do baroreceptors detect?
Changes in pressure, especially blood pressure.
40
What type of receptors are proprioceptors?
Mechanoreceptors.
41
What do thermoreceptors detect?
Changes in temperature.
42
What do chemoreceptors detect?
Chemical changes, such as changes in blood composition.
43
What do photoreceptors detect?
Light.
44
What do nociceptors detect?
Stimuli associated with pain.
45
What are the three main structural categories of sensory receptors?
Free nerve endings, encapsulated nerve endings, and specialized receptor cells.
46
What are free nerve endings?
Unencapsulated dendritic endings that mainly detect pain and temperature, while some detect light touch.
47
Where are free nerve endings especially abundant?
In epithelia and the underlying connective tissue.
48
What do free nerve endings mainly detect?
Pain and temperature; some also detect light touch.
49
What are encapsulated nerve endings?
Dendritic endings surrounded by connective tissue that receive sensory stimuli.
50
How does the capsule of an encapsulated nerve ending help it function?
It modifies sensitivity to stimuli and helps filter mechanical signals.
51
What do tactile (Meissner's) corpuscles detect?
Light touch.
52
Where are Meissner's corpuscles located?
In the papillary dermis.
53
What do lamellar (Pacinian) corpuscles detect?
Pressure, especially deep pressure and vibration.
54
Where are Pacinian corpuscles located?
In the reticular dermis and deeper tissues.
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What do bulbous corpuscles detect?
Stretching.
56
Where can bulbous corpuscles be found?
In joint capsules and the dermis.
57
What are specialized receptor cells?
Cells with specialized structures that detect specific stimuli.
58
Which specialized cells detect light in the retina?
Photoreceptors, including rods and cones.
59
What do the chemoreceptors in the carotid bodies detect?
Changes in the chemical composition of blood.
60
Where do carotid body chemoreceptors send signals?
To the cardiorespiratory centers in the medulla oblongata.
61
What blood changes stimulate carotid body chemoreceptors?
Decreased pH and oxygen levels, and increased carbon dioxide levels.
62
What response can stimulation of the carotid bodies produce?
An increase in breathing rate.
63
How is a peripheral sensory receptor fully classified?
By combining its functional classification with its structural classification.
64
How is a skin receptor that detects temperature classified?
As an exteroceptor, a thermoreceptor, and a free nerve ending.
65
How are receptors that detect oxygen and carbon dioxide in the blood classified?
As interoceptors, chemoreceptors, and specialized receptor cells.
66
How are receptors that detect muscle stretching classified?
As proprioceptors and mechanoreceptors; many are encapsulated nerve endings.
67
How are rods and cones in the retina classified?
As specialized photoreceptor cells and exteroceptors.
68
What are the two main types of cells in nervous tissue?
Neurons and neuroglia.
69
What distinguishes neurons from other nervous tissue cells?
They are excitable cells that generate and transmit nerve signals.
70
What is an action potential?
An electrical signal that propagates along a neuron's membrane.
71
What is neuroglia?
A group of non-neuronal support cells that help protect, support, and insulate nervous tissue.
72
Approximately how many neurons are in the average human brain?
About 86 billion.
73
What are the metabolic characteristics of neurons?
They have high glucose and oxygen requirements.
74
Do mature neurons normally divide?
No, mature neurons generally do not divide.
75
What is the soma of a neuron?
The cell body of the neuron.
76
What is the function of dendrites?
To receive signals and conduct them toward the cell body.
77
What is the axon hillock?
The region where the axon originates from the cell body and where an action potential usually begins.
78
What are axon terminals?
The endings of an axon that transmit signals to other cells.
79
What do vesicles in axon terminals contain?
Neurotransmitters.
80
What is chromatophilic substance?
Clusters of rough endoplasmic reticulum involved in protein synthesis.
81
What is the function of Schwann cells?
To wrap around PNS axons and form myelin sheaths around many of them.
82
What are nodes of Ranvier?
Gaps in the myelin sheath between adjacent myelinated segments.
83
What is the function of nodes of Ranvier in nerve conduction?
They allow saltatory conduction, in which the action potential is regenerated from node to node.
84
What are oligodendrocytes?
Glial cells in the CNS that form myelin sheaths around axons.
85
What is the sequence of signal transmission through a neuron?
Dendrites → cell body → axon → axon terminals → target cell.
86
How are neurons structurally classified?
According to the number of processes extending from the cell body.
87
How are neurons functionally classified?
According to the direction and function of their nerve impulses.
88
What structural type of neuron is common among sensory afferent neurons?
Unipolar or pseudounipolar.
89
What structural type of neuron is common among motor efferent neurons?
Multipolar.
90
What structural type of neuron is common among interneurons?
Multipolar.
91
What are the three main structural types of neurons?
Multipolar, bipolar, and unipolar.
92
What is a synapse?
The site where a nerve signal is transmitted between a neuron and another cell.
93
Between what types of cells can synapses form?
Between two neurons or between a neuron and a muscle or gland cell.
94
What is a presynaptic cell?
The cell that transmits the signal toward the synapse.
95
What is a postsynaptic cell?
The cell that receives the signal across the synapse.
96
What are the general functions of neuroglia?
Support, protection, insulation of nerve fibers, and maintenance of the neuronal environment.
97
What are the four main types of neuroglia in the CNS?
Astrocytes, microglia, ependymal cells, and oligodendrocytes.
98
What are the two main types of neuroglia in the PNS?
Satellite cells and Schwann cells.
99
What are astrocytes?
The most abundant glial cells in the CNS, with processes that contact neurons and capillaries.
100
What is the role of astrocytes in the blood-brain barrier?
They help maintain the barrier that restricts the movement of many substances from the blood into brain tissue.
101
What is the blood-brain barrier (BBB)?
A selective barrier that limits the passage of substances from the blood into brain tissue.
102
What substances can cross the blood-brain barrier under normal conditions?
Water, glucose, ions, and amino acids can cross through selective mechanisms.
103
What other functions do astrocytes perform?
They regulate neurotransmitters and extracellular ions, help regulate blood flow, and respond to tissue damage.
104
What are microglia?
Resident immune cells of the CNS that perform phagocytosis and defense.
105
What is the main function of microglia?
To remove cellular debris and harmful agents through phagocytosis.
106
What are ependymal cells?
Cells that line the brain's ventricles and the central canal of the spinal cord.
107
What is the function of ependymal cells?
They participate in cerebrospinal fluid production and circulation and form a lining between the fluid and nervous tissue.
108
What are oligodendrocytes?
Glial cells in the CNS that wrap around axons and form myelin.
109
What is the function of satellite cells?
They surround neuronal cell bodies in the PNS and regulate their local environment.
110
What is the function of Schwann cells in the PNS?
They surround axons and form myelin around many of them.
111
What is the myelin sheath?
A lipid- and protein-rich covering that electrically insulates certain axons.
112
How does myelin affect nerve conduction?
It reduces current leakage and increases the speed of nerve impulse conduction.
113
What is a nerve?
A bundle of axons located in the PNS.
114
What is a nerve tract?
A bundle of axons traveling together within the CNS.
115
What is a collection of neuronal cell bodies called in the PNS?
A ganglion; plural, ganglia.
116
What is a collection of neuronal cell bodies called in the CNS?
A nucleus; plural, nuclei.
117
What are ascending tracts?
CNS tracts that carry information toward higher regions, such as the brain.
118
What are descending tracts?
CNS tracts that carry signals from the brain toward lower regions, such as the spinal cord.
119
What is white matter in the CNS?
A region consisting mainly of axons, many of which are myelinated, and neuroglia.
120
What structures are mainly found in white matter?
Nerve tracts.
121
What is gray matter in the CNS?
A region containing mainly neuronal cell bodies, dendrites, synapses, and neuroglia, along with unmyelinated axons.
122
What structures are organized into groups in the gray matter of the CNS?
Neuronal nuclei, among other structures.
123
Where do many CNS synapses occur?
In the gray matter.
124
What is neuronal integration?
The processing of nervous system information that allows sensory input to be converted into motor output.
125
What is a reflex?
A rapid, automatic motor response to a sensory stimulus.
126
What is a reflex arc?
The neural circuit that produces a reflex response.
127
Where is a simple spinal reflex integrated?
In the spinal cord, without waiting for the brain to process the signal.
128
What is a monosynaptic reflex?
A reflex whose basic circuit contains one synapse and no interneurons.
129
What is an example of a monosynaptic reflex?
The patellar reflex, or knee-jerk stretch reflex.
130
What is a polysynaptic reflex?
A reflex that contains two or more synapses and one or more interneurons.
131
What is an example of a polysynaptic reflex?
The withdrawal reflex that moves the hand away from a hot object.
132
What is serial processing?
The processing of information through a sequence of steps.
133
What is parallel processing in the nervous system?
The simultaneous processing of information by different neural pathways.
134
What happens first when you touch a hot object?
A withdrawal reflex is activated, allowing the hand to move away quickly.
135
Which pathway carries pain information from the spinal cord to the brain?
An ascending tract, such as the spinothalamic tract.
136
What happens when the brain consciously processes pain?
It integrates sensory information and can generate motor commands to modify the response.
137
How can the brain produce a voluntary movement?
Signals travel down motor tracts and activate efferent neurons that stimulate muscles.
138
What is the main difference between a spinal reflex and a conscious motor response?
A reflex can be integrated rapidly in the spinal cord, while a conscious response requires processing in the brain
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