Nervous system chapter 12

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1
What are the three main functions of the nervous system?
Sensory input, integration, and motor output What is the overall function of the nervous system?
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What are the three main functions of the nervous system?
Sensory input, integration, and motor output
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What is the overall function of the nervous system?
To sense and respond to external or internal changes in the body through voluntary or involuntary responses
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What are the two main divisions of the nervous system?
Central nervous system (CNS) and peripheral nervous system (PNS)
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What structures make up the central nervous system (CNS)?
The brain and spinal cord
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What is the main role of the CNS?
To receive, interpret, integrate, and respond to signals from the PNS
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What structures make up the peripheral nervous system (PNS)?
Cranial nerves and spinal nerves
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What is the main role of the PNS?
To carry sensory information to the CNS and motor commands from the CNS to effectors
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What is the general pathway of information through the nervous system?
PNS → CNS → PNS
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What is the sensory division of the PNS called?
The afferent division
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What is the function of afferent neurons?
To carry sensory information from receptors toward the CNS
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What is the motor division of the PNS called?
The efferent division
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What is the function of efferent neurons?
To carry motor commands from the CNS to effectors
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What is an easy way to remember afferent?
Afferent arrives at the CNS
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What is an easy way to remember efferent?
Efferent exits the CNS
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What is the correct order of sensory input, integration, and motor output?
Sensory input → CNS integration → Motor output
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What are the four basic steps in nervous system communication?
Afferent division brings information to the CNS; the CNS integrates the signals; the CNS sends commands to the efferent division; the efferent division carries commands to effectors
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What is an interneuron?
A neuron located entirely within the CNS that receives, integrates, and relays information between neurons
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Where are interneurons located?
Exclusively in the CNS
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What is the function of interneurons?
To process and relay information between sensory and motor neurons
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What is the difference between sensory and motor neurons?
Sensory neurons carry information toward the CNS, while motor neurons carry commands away from the CNS
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Where do cranial nerves originate?
From the brain; many originate from the brainstem
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What does somatic mean?
Relating to the body, particularly the skin, skeletal muscles, and bones
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What are examples of somatic structures?
Skin, skeletal muscles, and bones
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What does visceral mean?
Relating to internal organs and structures
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What are examples of visceral structures?
Digestive organs, spleen, bladder, heart, and lungs
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What is the difference between somatic and visceral sensory information?
Somatic information comes from the body wall and musculoskeletal system, while visceral information comes from internal organs
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What is the autonomic nervous system responsible for?
Regulating involuntary functions of internal organs, glands, cardiac muscle, and smooth muscle
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What are the two main divisions of the autonomic nervous system?
Sympathetic and parasympathetic divisions
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What is the main function of the sympathetic division?
Prepares the body for fight-or-flight responses
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What is the main function of the parasympathetic division?
Promotes rest-and-digest activities
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What is an effector?
A muscle, gland, or other target that carries out a response to a motor command
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What are examples of nervous system effectors?
Skeletal muscles, smooth muscles, cardiac muscle, and glands
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What is the function of sensory receptors?
To detect stimuli from the internal or external environment
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How does sensory information reach the CNS?
Sensory receptors detect stimuli, and afferent nerves carry the information to the brain or spinal cord
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What can the spinal cord do with sensory information?
Relay it to the brain or integrate it locally to produce a spinal reflex
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How does the brain process sensory information?
Specialized brain regions process and integrate sensory information and help determine an appropriate response
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How do motor commands reach effectors?
Through efferent nerves, often via the spinal cord or directly through cranial nerves
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What is a spinal reflex?
A rapid, automatic response integrated in the spinal cord
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What are the two main ways to classify peripheral sensory receptors?
By receptor location and by the type of stimulus detected
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What is an exteroceptor?
A receptor that detects stimuli from outside the body
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Where are exteroceptors commonly found?
In the skin and special sense organs
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What stimuli can exteroceptors detect?
Touch, pressure, pain, temperature, smell, hearing, taste, and vision
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What is an interoceptor?
A receptor that detects stimuli from internal organs and the body's internal environment
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What is another name for interoceptors?
Visceroceptors
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What stimuli can interoceptors detect?
Changes in internal chemistry, organ stretch, and other conditions within the viscera
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What is a proprioceptor?
A receptor that detects the position and movement of the body by sensing stretch in muscles, tendons, ligaments, and joints
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What information do proprioceptors send to the CNS?
Information about body position and movement
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What is a mechanoreceptor?
A receptor that detects mechanical forces such as touch, pressure, stretch, or vibration
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What is a baroreceptor?
A mechanoreceptor that detects changes in pressure, such as blood pressure
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What type of receptor is a proprioceptor?
A mechanoreceptor
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What is a thermoreceptor?
A receptor that detects temperature changes
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What is a chemoreceptor?
A receptor that detects chemical changes
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What is an example of a stimulus detected by chemoreceptors?
Changes in blood oxygen, carbon dioxide, or pH
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What is a photoreceptor?
A receptor that detects light
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What is a nociceptor?
A receptor that detects potentially damaging stimuli associated with pain
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What is the difference between functional and structural classification of sensory receptors?
Functional classification describes what stimuli receptors detect or where they are located; structural classification describes their physical structure
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What is a free nerve ending?
A sensory receptor formed by exposed nerve endings embedded in tissues
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Where are free nerve endings commonly found?
In many tissues, particularly epithelia and connective tissue beneath epithelia
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What sensations do free nerve endings commonly detect?
Pain and temperature; some also detect light touch
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What is an encapsulated nerve ending?
A sensory nerve ending surrounded by connective tissue that helps modify or enhance its sensitivity to stimuli
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What is the function of the capsule surrounding an encapsulated nerve ending?
It can increase sensitivity to particular signals and filter mechanical stimuli
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Where are tactile (Meissner's) corpuscles located?
Primarily in the papillary dermis
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What do tactile (Meissner's) corpuscles detect?
Light touch
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Where are lamellar (Pacinian) corpuscles found?
In deeper connective tissues, including the deep dermis and subcutaneous tissues
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What do lamellar (Pacinian) corpuscles detect?
Deep pressure and vibration
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What do bulbous corpuscles detect?
Stretch of the skin or other tissues
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What are examples of proprioceptors?
Muscle spindles and other receptors in muscles, tendons, and joints
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What is a specialized sensory receptor cell?
A specialized cell with structures that detect a particular stimulus and communicate the information to neurons
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What is an example of a specialized sensory receptor cell?
A photoreceptor cell in the retina
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What do rods and cones detect?
Light
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What do specialized chemoreceptors in the carotid bodies detect?
Changes in blood chemistry, including oxygen, carbon dioxide, and pH
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Where do carotid body chemoreceptors send their signals?
To cardiorespiratory control centers in the medulla
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What happens when blood oxygen or pH decreases or carbon dioxide increases?
Chemoreceptors stimulate signals to the medulla that can increase breathing rate
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How would you classify a skin receptor detecting temperature by location and stimulus?
An exteroceptor and a thermoreceptor
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How would you classify a receptor detecting blood oxygen levels by location and stimulus?
An interoceptor and a chemoreceptor
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How would you classify a receptor detecting skeletal muscle stretch by location and stimulus?
A proprioceptor and a mechanoreceptor
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How would you classify retinal rods and cones by location and stimulus?
Exteroceptors and photoreceptors
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Why should sensory receptors be classified both structurally and functionally?
The two classifications describe different features and together provide a fuller description of a receptor
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What are the two main types of cells in nervous tissue?
Neurons and neuroglia
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What is the primary function of neurons?
To receive and transmit electrical signals and communicate with other cells
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What is the primary function of neuroglia?
To support, protect, nourish, and insulate neurons and help maintain the nervous system environment
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What is a nerve impulse?
An electrical signal transmitted along a neuron's plasma membrane, usually through an action potential
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What is an action potential?
A rapid change in membrane voltage that propagates along an excitable cell membrane
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Approximately how many neurons are in the average human brain?
About 86 billion
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Why do neurons require high levels of oxygen and glucose?
They have high metabolic demands to maintain their functions and signaling
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Do most mature neurons divide?
Most mature neurons do not divide
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How long can neurons survive?
Some neurons can survive for many decades, potentially for a person's entire lifetime
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What is the soma of a neuron?
The cell body containing the nucleus and much of the cell's machinery
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What is the function of dendrites?
To receive signals and generally carry them toward the cell body
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What is the axon hillock?
The region where the cell body connects to the axon and where action potentials are commonly initiated
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What is the function of an axon?
To conduct electrical signals away from the cell body toward the axon terminals
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What are axon terminals?
The ends of an axon that communicate with another neuron, muscle, or gland
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What are terminal boutons?
Swollen endings of axon terminals that contain synaptic vesicles
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What is stored in synaptic vesicles?
Neurotransmitters
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What is chromatophilic substance?
Clusters of rough endoplasmic reticulum and associated ribosomes involved in protein synthesis in neurons
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What is the correct direction of signal flow through a typical neuron?
Dendrites → cell body → axon → axon terminals → target cell
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What is a Schwann cell?
A type of neuroglial cell in the PNS that wraps around axons and can form myelin
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What is the function of the myelin sheath?
To insulate axons and increase the speed of nerve impulse propagation
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What is a node of Ranvier?
A gap between adjacent myelin segments along an axon
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What happens at the nodes of Ranvier?
Action potentials are regenerated, allowing impulses to travel rapidly by saltatory conduction
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What are oligodendrocytes?
CNS neuroglia that form myelin sheaths around axons
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What is the difference between Schwann cells and oligodendrocytes?
Schwann cells myelinate axons in the PNS, while oligodendrocytes myelinate axons in the CNS
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How are neurons structurally classified?
By the number of processes extending from the cell body
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What are the three main structural classes of neurons?
Multipolar, bipolar, and unipolar neurons
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What is a multipolar neuron?
A neuron with one axon and multiple dendrites
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What is a bipolar neuron?
A neuron with one dendrite and one axon
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What is a unipolar neuron?
A neuron with a single process extending from the cell body; sensory neurons are commonly pseudounipolar
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How are neurons functionally classified?
By the direction in which they transmit information and their role in the nervous system
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What is the typical structural type of a sensory neuron?
Pseudounipolar
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What is the typical structural type of a motor neuron?
Multipolar
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What is the typical structural type of an interneuron?
Multipolar
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What is a synapse?
A site where a neuron communicates with another neuron or a target cell
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What is the presynaptic cell?
The cell that sends a signal into a synapse
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What is the postsynaptic cell?
The cell that receives a signal across a synapse
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Can a neuron be both presynaptic and postsynaptic?
Yes, a neuron can receive signals at some synapses and send signals at others
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What are the six main types of neuroglia?
Astrocytes, microglia, ependymal cells, oligodendrocytes, satellite cells, and Schwann cells
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Which four types of neuroglia are found in the CNS?
Astrocytes, microglia, ependymal cells, and oligodendrocytes
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Which two types of neuroglia are found in the PNS?
Satellite cells and Schwann cells
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What are astrocytes?
Star-shaped CNS neuroglia that support neurons and help regulate the chemical environment
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What is one major function of astrocytes?
Helping maintain the blood-brain barrier
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What is the blood-brain barrier (BBB)?
A selective barrier that restricts the movement of many substances from the blood into brain tissue
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Why is the blood-brain barrier important?
It helps maintain a stable chemical environment for neurons and protects brain tissue from many harmful substances
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What substances can cross the blood-brain barrier under normal conditions?
Substances such as glucose, water, ions, and amino acids can cross through regulated pathways
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How do astrocytes help regulate the brain's chemical environment?
They help regulate extracellular ion concentrations and take up and recycle neurotransmitters
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How do astrocytes contribute to blood flow regulation?
They communicate with blood vessels and help coordinate local blood flow with neural activity
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What are microglia?
Immune-related neuroglia in the CNS that defend nervous tissue and remove debris
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What is the main function of microglia?
Phagocytosis and immune defense
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What type of cells are microglia similar to?
Macrophages
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What are ependymal cells?
Cells that line the ventricles of the brain and the central canal of the spinal cord
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What is the function of ependymal cells?
They help form the boundary between cerebrospinal fluid and nervous tissue and are involved in CSF production and circulation
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What is cerebrospinal fluid (CSF)?
Fluid that surrounds the brain and spinal cord and helps protect and support the CNS
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Where are the ventricles located?
Within the brain
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Where is the central canal located?
Within the spinal cord
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What are oligodendrocytes responsible for?
Forming myelin sheaths around CNS axons
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What are satellite cells?
PNS neuroglia that surround neuronal cell bodies in ganglia
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What is the function of satellite cells?
To support neuronal cell bodies and regulate their local chemical environment
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What are Schwann cells responsible for?
Supporting PNS axons and forming myelin sheaths around them
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What is myelin made from?
Layers of glial cell plasma membrane rich in lipids and proteins
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How does myelin increase nerve impulse speed?
It reduces current leakage and allows action potentials to be regenerated at nodes of Ranvier
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What is a nerve?
A bundle of axons located in the PNS
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What is a tract?
A bundle of axons located in the CNS
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What is a ganglion?
A collection of neuronal cell bodies located in the PNS
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What is the plural of ganglion?
Ganglia
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What is a nucleus in the nervous system?
A collection of neuronal cell bodies located in the CNS
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What is the plural of nucleus?
Nuclei
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What is the difference between a nerve and a tract?
A nerve is a bundle of axons in the PNS, while a tract is a bundle of axons in the CNS
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What is the difference between a ganglion and a nucleus?
A ganglion is a collection of neuronal cell bodies in the PNS, while a nucleus is a collection of neuronal cell bodies in the CNS
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What is white matter?
CNS tissue composed primarily of myelinated axons and neuroglia
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What structures are found in white matter?
Tracts
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What is gray matter?
CNS tissue containing neuronal cell bodies, dendrites, synapses, neuroglia, and some unmyelinated axons
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What structures are found in gray matter?
Nuclei and other regions containing neuronal cell bodies and synapses
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Where do most neuronal synapses occur in the CNS?
In gray matter
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What are ascending tracts?
CNS pathways that carry information upward, typically from the spinal cord toward the brain
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What are descending tracts?
CNS pathways that carry commands from the brain toward lower CNS regions, including the spinal cord
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How does sensory information travel from the skin to the brain?
Receptors detect stimuli; sensory nerves carry signals through the PNS; CNS pathways carry the information through tracts to the brain
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How do motor commands travel from the brain to an effector?
Commands travel through descending CNS pathways, synapse with motor neurons, and reach effectors through PNS nerves
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What is neuronal integration?
The processing and integration of nervous system information to help convert sensory input into an appropriate response
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What is a reflex?
A rapid, automatic response to a stimulus
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What is a reflex arc?
The neural pathway that produces a reflex response
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What is the simplest type of neuronal integration?
A reflex arc
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Where are many basic spinal reflexes integrated?
In the spinal cord
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What is a monosynaptic reflex?
A reflex involving one synapse between a sensory neuron and a motor neuron
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Does a monosynaptic reflex require an interneuron?
No
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What is an example of a monosynaptic reflex?
The knee-jerk stretch reflex
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What is a polysynaptic reflex?
A reflex involving two or more synapses and at least one interneuron
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What is an example of a polysynaptic reflex?
The withdrawal reflex
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Which type of reflex is more common, monosynaptic or polysynaptic?
Polysynaptic reflexes
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What is the withdrawal reflex?
A rapid, automatic response that moves a body part away from a potentially harmful stimulus
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What is serial processing in the context of a withdrawal reflex?
A sequence of neural processing steps that produces a rapid reflex response
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What happens during the rapid withdrawal response to a hot object?
A sensory neuron carries information to the spinal cord, interneurons process it, and motor neurons activate muscles to withdraw the hand
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Does the initial withdrawal reflex require the brain to initiate the movement?
No, the spinal cord can integrate the reflex and initiate the motor response
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What is parallel processing in nervous system function?
The simultaneous processing of information by different neural pathways
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How can withdrawal from a hot object and pain perception occur together?
The spinal cord initiates a rapid withdrawal reflex while ascending pathways carry sensory information to the brain for pain perception
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What is the role of the spinothalamic tract in pain perception?
It carries pain and temperature information toward the brain, including the thalamus
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What happens after pain information reaches the brain?
The brain processes the sensation and can generate additional motor commands
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How can the brain voluntarily respond after touching a hot object?
The brain processes the pain and sends motor commands through descending tracts to motor neurons that activate muscles
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What is the difference between the initial withdrawal reflex and the later voluntary response?
The withdrawal reflex is rapid and integrated in the spinal cord, while the later voluntary response involves processing and decision-making by the brain
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What is the general role of ascending pathways?
To carry sensory information toward the brain
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What is the general role of descending pathways?
To carry motor commands from the brain toward lower CNS regions
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What is the difference between sensory input and motor output?
Sensory input carries information from receptors to the CNS, while motor output carries commands from the CNS to effectors
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What is the overall pathway for a typical sensory-motor response?
Stimulus → sensory receptor → afferent neuron → CNS integration → efferent neuron → effector → response
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What is the difference between voluntary and involuntary nervous system responses?
Voluntary responses involve conscious control, while involuntary responses occur automatically without requiring conscious control
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What is the main purpose of classifying neurons by structure and function?
Structural classification describes the number of processes, while functional classification describes the neuron's role and direction of information flow
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