1result from deficiency of norepinephrine(NE), Dopamine or Serotonin (5HT)
Depression
2It inhibits the effects of MAO, leading to increase NE and 5HT in the synaptic cleft
Actions of Antidepressants Therapy
3A person's mood goes far beyond the normal "ups and downs"
Affective Disorder
4Lack of voluntary coordinations of muscle movements.
Ataxia
5It reduce the reuptake of 5HT and NE into nerves
Tricyclic Antidepressants
6Are all TCAs oral medications?
Yes. That's a fact bitch.
7What is PANAMA?
Parnate, Nardil and Marplan
8This irreversibly inhibits MAOs. allowing norepinephrine, serotonin and dopamine to accumulate in the synaptic cleft.
Monoamine Oxidase Antidepressants ( MAOIs)
9This is used for patients cannot take newer, safer antidepressants
Marplan (Isocarboxazid)
10Used for some patients who do not respond to newer, safer antidepressants
Nardil (Phenelzine)
11Used for adult outpatients with reactive depression
Parnate (Tranylcypromine)
12It specifically block the reuptake of 5HT and the newest group of antidepressant drugs
Selective Serotonin Reuptake Inhibitors (SSRIs)
13Extreme sadness or mood shift
Dysphoric Disorder
14Two moods in bipolar
Manic (extreme happiness) and Depressive (extreme sadness)
15It is the safest antihypertensive medication to ob patient
Methyldopa
16What is it callednif you have too much nitrogen, creatinine and other waste product in your blood?
Azotemia
17It treats bipolar manic depressive psychosis or manic episodes
Lithium
18Trade names of Lithium?
Eskalith, Lithane, Lithonate, Lithobid
19Create fake messages in the brain. Majority of these drugs are controlled substances.
CNS Stimulants
203 Cardinal signs of ADHD. Clue: IHI
Inattention/Lack of attention, Hyperactivity, Impulsivity
21It is responsible for our sleep-wake cycle
Reticular Activated System (RAS)
22Stimulates release of neurottansmitters (dopamine and norepinephrine) causing euphoria and alertness
Amphetamines
23Produces CNS and respiratory stimulation with weak sympathomimetic activity
Amphetamine Like Drugs
24Stimulates CNS activity, it also suppresses appetite
Anorexiant
25Affects brainstem, spinal cord and cerebral cortex, relaxes bronchial smooth muscle, increases heart rate and blood pressure.
Analeptic
26In low dose, it stimulates carotid receptors. In higher dose, it stimulates respiratory center in medulla, produces generalized CNS stimulations.
Respiratory CNS Stimulant
27Unilateral throbbing (usually in temporal).
Migraine Headache
28Caused by inflammation and dilation of cranial blood vessels.
Migraine Headache
29Preventive treatments for migraine
Vasoconstriction like beta blockers (Propanolol and Atenolol), Anticonvulsant (Gabapentin, Topiramate amd Valproic acid) and TCAs (Amitryptyline and Imipramine)
30Trratment for migraine
Analgesics like Opiod, NSAIDS and Hydrocodone with ibprofen. Ergot Alkaloids like Ertotamine Tartrate
31Slow messages between the brain and body and cause varying degrees of depression (reduction in functional activity)
CNS Depressants
32Broad Classifications of CNS depressants
edi wow
33class of drugs that cause a dose-dependent depression of the CNS function.
Sedative Hypnotics
34Agents in this class of drugs includes benzodiazepines amd Z-drugs, barbiturates and melatonin agonists.
Sedative Hypnotics
352 classification of anesthetics
General Anethetics and Local Anesthetics
36Depresses the CNS, alleviate pain and cause LOSS OF CONCIOUSNESS
General Anesthetics
37Block pain at the site where the drug is administered
Local Anesthetics