1The prediction of the course and end of a disease and an outlook based on that prediction best define its:
a. Diagnosis
b. Etiology
c. Prognosis
d. Syndrome
Prognosis
2A compression fracture of the lumbar spine that results from steroid treatments for pain reduction of arthritis would be an example of _______ disease.
a. Degenerative
b. Iatrogenic
c. Idiopathic
d. Traumatic
Latrogenic
3A disease such as Tay-Sachs syndrome that is transmitted genetically is termed:
a. Congenital
b. Hereditary
c. Metabolic
d. Neoplastic
Hereditary
4Sickness sufficient to interfere with one's normal daily routine refers to its:
a. Etiology
b. Morbidity
c. Mortality
d. Pathogenesis
Morbidity
5Which of the following would be considered a symptom of a disease process?
a. Bloody stool
b. Nausea
c. Skin rash
d. Swelling
Nausea
6A disease that manifests slowly and is present for a long period is said to be:
a. Acute
b. Asymptomatic
c. Chronic
d. Congenital
Chronic
7Which of the following disease classifications is usually associated with the normal aging process?
a. Congenital
b. Degenerative
c. Inflammatory
d. Metabolic
Degenerative
8If 4000 cases of a given disease are found in a given population, the _______ of the disease is defined.
a. Incidence
b. Morphology
c. Metabolism
d. Prevalence
Prevalence
9The relative ease with which an organism can overcome normal bodily defenses refers to its:
a. Infection
b. Necrosis
c. Pestilence
d. Virulence
Virulence
10A neoplastic growth is evaluated to determine its degree of histologic differentiation. This is termed:
a. Grading
b. Metastasis
c. Morphology
d. Staging
Grading
11Generalized increase in cell size refers to:
a. Hypertrophy
b. Atrophy
c. Metaplasia
d. Hyperplasia
Hypertrophy
12Which of the following terms refers to abnormal changes of mature cells?
a. Hypertrophy
b. Dysplasia
c. Metaplasia
d. Hyperplasia
Dysplasia
13Explain the concept of neoplastic disease. Are all neoplasms cancer?
A neoplasm or neoplastic disease is new, abnormal tissue growth resulting from mutations within the chromosomes of the cell (genetic instability). Classification of the neoplasm depends on the tissue type of the tumor. Neoplasms can be benign or malignant. Only malignant neoplasms are cancer.
14What is the difference between mortality and morbidity rate? How is each important to the practice of medicine and to public health agencies?
The mortality rate is the average number of deaths caused by a particular disease in a population. Monitoring and reporting mortality rates provides the leading causes of death according to gender, race, age, and specific causes of death such as heart disease or malignant neoplasia. Trends in these mortality patterns are identified by age, gender, and ethnic origin and tracked to help identify necessary interventions. The morbidity rate is the incidence of sickness sufficient to interfere with an individual's normal daily routine. Tracking the morbidity rate helps to monitor prevalent illnesses in a particular population or geographic areas.
15Differentiate between an acute and chronic illness. Give two examples of each.
Acute diseases usually have a quick onset and last for a short period, whereas chronic diseases may manifest more slowly and last for a very long time. Examples of acute illnesses are pneumonia or influenza, whereas examples of chronic illnesses are chronic obstructive pulmonary disease or multiple myeloma.
16What is pathology?
study of disease
17What is a disease?
any abnormal disturbance of the function or structure of the human body as a result of some type of injury.
18What is pathogenesis?
he sequence of events producing cellular changes that ultimately lead to observable changes know as Manifestations
19What is a symptom?
subjective sensation that the person feels from the disorder
20What is a sign?
An objective manifestation that can be detected by the physician
21What is etiology?
the study of the cause of disease
22What is nosocomial?
hospital acquired infection
23What is latrogenic?
adverse responses to medical treatment.
24What is idiopathic?
cause of disease is unknown
25What is an acute disease?
usually has a quick onset, last a short period
26What is chronic disease?
may comes on slowly, lasts long time
27What is sequelae condition?
a condition caused by previously acquired disease.
28What is the term diagnosis?
identification of a disease
29What is the term prognosis?
predicted course and outcome
30What is morphology?
The structure of cells or tissue
31What is Subtractive/lytic/destructive?
Require decrease in exposure technique
"ex"- Emphysema
32what is Additive/sclerotic?
Require increase in exposure technique
"ex"- pneumonia
33What is Epidiomology
investigation of disease in large groups.
34what is prevalence?
number of cases found in a given population.
35What is incidence?
number of new cases found in a given population
36What is endemic?
disease of high prevalence in an area where a given causative organism is commonly found .
37what is epidemic?
a rapid, widespread occurrence in a large number of people in a population.
38what is a pandemic?
an epidemic affecting the majority of a population of a large region or an epidemic occurring at the same time in many different parts of the world.
39What is mortality rate?
average number of deaths caused by a disease in a population
40what does NCHS stand for and what does it mean?
National Center for Health Statistics and its the centers for Disease Control and Prevention (CDC)
41What is morbidity rate?
the incidence of sickness sufficient to interfere with an individual's normal daily routine
42What is the genome of an organism?
With the exception of reproductive (germ) cells, each cell in the human body contains 22 pairs of autosomal chromosomes, two sex chromosomes (XX or XY), and the small chromosome found in each mitochondria within the cell.
43What do physical maps determine?
they determine the physical location of a particular gene on a specific chromosome.
44What do genetic maps do?
they assign the distance between genetic markers, linking DNA fragments to a specific chromosome.
45what is a single-nucleotide polymorphisms (SNPs)
Variations in the DNA sequence due to the change of a single nitrogen base.
46What is a haplotype?
comprises closely linked SNPs on a single chromosome, and it is a very important resource in identifying specific DNA sequences that affect disease, response to pharmaceuticals, and response to environmental factors.
47What is atrophy?
decrease in cell size
48What is hypertrophy?
increase in cell size
49What is hyperplasia?
increase in number of cells
50What is metaplasia?
conversion to another cell type that is not normal.
51what is dysplasia?
change in mature cells that is not normal. Precancerous.
52what is congenital?
Diseases that are present at birth from genetic or environmental factors.
53What is heredity?
Diseases caused by developmental disorders genetically transmitted from either parent to a child.
54What is autosomal?
abnormality present on one of the 22 non-sex chromosomes
55what is inflammatory?
Disease that results from the body's reaction to a localized injurious agent
56what is an autoimmune disorder?
Disease in which the body forms antibodies that injure patient's own tissues
57What does infection mean?
refers to an inflammatory process caused by a disease-causing organism
58What does virulence mean?
the ease with which an organism can cause disease.
59what does degenerative mean?
Disease caused by a deterioration of the body
60what is metabolism?
The sum of all physical and chemical processes int he body
61what is metabolic syndrome?
Disease caused by the disturbance of the normal physiologic function of the body
62what is traumatic disease?
Disease that may result from mechanical forces such as crushing or twisting of a body part or from the effects of ionizing radiation on the body
63What is a neoplastic disease?
disease that results in new, abnormal tissue growth
64what is Benign neoplasm?
composed of well-differentiated cells with uncontrolled growth "BE NICE"
65what is Malignant neoplasm?
grow fast, spread and invade
66what is Metastatic spread?
Bacteria is distributed around the body through the blood stream.
67What is hematogenous spread?
spread through the blood
68what is Lymphatic spread?
neoplasm drains to the sentinel node
69what is Invasion?
if the cancerous cells spread into surrounding tissues by virtue "of proximity"
70what does seeding mean?
travel to distant site or organ system
71what is a lesion?
cellular changes that may occur in response to diseases.
72what is cancer?
general term refers to many types of malignant neoplasms
73what is a carcinoma?
derived from epithelial tissue
74what are sarcomas?
connective tissue cancers
75What is leukemia?
A cancer of white blood cells/leukocytes.
76What is lymphoma?
cancer of the lymph nodes
77what is TNM?
tumor-node-metastasis
78What are the various agents that can induce cell necrosis?
The various agents that can induce cell necrosis are local and systemic effects.
79what is Excess mortality?
Excess mortality is used with the public health to determine the number of deaths that have occurred and the causes from these deaths
80Under what conditions might a Rad Tech have an encounter with a Sickle Cell patient?
The conditions where a Rad Tech might have an encounter with a sickle cell patient is either in X-ray, MRI, CT or in ultrasound. Some sickle cell can be diagnosed or monitored with either of these imaging test.
81Specialized cells responsible for the absorption of bone tissue during growth and healing are termed:
a. Chondroblasts
b. Osteoblasts
c. Osteoclasts
d. Both b and c
Osteoclasts
82A firm, immovable joint is classified as:
a. Amphiarthrodial
b. Diarthrodial
c. Synarthrodial
d. Triarthrodial
Synarthrodial
83The medullary cavity is made up of:
a. Cancellous bone
b. Compact bone
c. Trabeculae
d. Cortical bone
Cancellous bone
84The growth zone of a lone bone is referred to as the:
a. Epiphysis
b. Diaphysis
c. Diploë
d. Metaphysis
Metaphysis
85What is the most common primary bone malignancy found in children and adolescents?
a. Giant cell tumor
b. Osteoid osteoma
c. Osteosarcoma
d. Osteochondroma
Osteosarcoma
86The most common inherited disorder that results in dwarfism is:
a. Osteogenesis
b. Albers-Schönberg disease
c. Spina bifida imperfecta
d. Achondroplasia
Achondroplasia
87A variant of rheumatoid arthritis associated with pain, swelling, and stiffness in people under 16 years old is:
a. Juvenile arthritis
b. Psoriatic arthritis
c. Osteoarthritis
d. Reiter syndrome
Juvenile arthritis
88A congenital malformation of the foot characterized by a plantar flexion deformity is termed:
a. Adactyly
b. Polydactyly
c. Syndactyly
d. Talipes equinovarus
Talipes equinovarus
89An abnormal lateral deviation of the spine is referred to as:
a. Scoliosis
b. Klippel-Feil syndrome
c. Ankylosing spondylitis
d. Achondroplasia
Scoliosis
90An infectious disease of the skeletal system is:
a. Rheumatoid arthritis
b. Osteomyelitis
c. Osteosarcoma
d. Klippel-Feil syndrome
Osteomyelitis
91Osteoarthritis affects the weight-bearing joints within the body and may be treated with:
a. Exercise
b. Medication
c. Surgery
d. All of the above
All of the above
92The type of arthritis characterized by the presence of Heberden nodes is:
a. Bursitis
b. Gout
c. Osteoarthritis
d. Rheumatoid arthritis
Osteoarthritis
93A malformation of the acetabulum which causes the femoral head to be displaced is termed:
a. Avascular necrosis
b. Developmental dysplasia of the hip
c. Talipes equinovarus
d. Craniotubular dysplasias
Developmental dysplasia of the hip
94The most common benign bone tumor is:
a. Osteoid osteoma
b. Osteochondroma
c. Enchondroma
d. Osteoma
Osteochondroma
95All of the following are malignant neoplasms of the skeletal system except:
a. Enchondroma
b. Ewing sarcoma
c. Osteosarcoma
d. Multiple myeloma
Enchondroma
96A 60-year-old male patient presents to the emergency department with worsening pain and decreased range of motion in his left knee. His pain is worse in the morning and improves with movement. If you were this patient's physician, what imaging test might you order, and why?
MRI is extremely useful in the evaluation of joints, particularly the knee and the shoulder, particularly in providing soft tissue detail because of its superior contrast resolution and ability to image in multiple planes.
97A 2-month-old female is brought to her pediatrician's office with complaints of clicking and laxity in her right hip. What might be the initial suspicion, and what diagnostic procedure(s) might be ordered?
The condition is most likely developmental dysplasia of the hip. Sonography may be used to diagnose this anomaly early in life through visualization of the cartilaginous structures of the hip. Conventional radiographs of the hip are often difficult to interpret in the neonate.
98How may CT and MRI be used to complement skeletal radiography in the diagnosis and treatment of enchondroma?
CT and MRI are useful in distinguishing enchondromas from chondrosarcomas and both modalities may be used to guide a biopsy of the neoplasm.
99A 75-year-old male patient presents to his physician's office with increasing low back pain. He has a prior history of colon cancer, which was treated 8 months ago with surgery and chemotherapy. What might be the initial suspicion, and what radiologic procedure(s) should be performed?
The spine is the most common site for bone metastasis to occur, accounting for approximately 40% of all metastatic lesions. CT is often employed, especially for imaging the spine and MRI may also be used to differentiate between tumor tissue and normal bone marrow. Recently whole body FDG-PET, whole body MRI, MRI-PET, and CT-PET have been advocated for imaging metastatic disease.
100In diagnosing bone tumors, what are some of the characteristics taken into consideration?
Primary bone tumors are more common in children than in adults, and metastatic bone lesions far outnumber the incidence of primary bone neoplasms in the adult. The most common benign tumors are osteoma, osteochondroma, and giant cell tumor. The primary malignant bone tumors are osteosarcoma, Ewing's sarcoma, and multiple myeloma. The diagnosis of a bone abnormality is often made radiographically on the basis of the individual's age, the pattern of bone destruction, the location of the tumor, and the tumor's position within the bone.
101What is achondroplasia?
A hereditary, congenital disturbance that causes inadequate bone formation and results in a peculiar form of dwarfism
102What is Albers-Schonberg disease?
A form of osteosclerotic osteopetrosis
103 a benign skeletal anomaly that involves increased bone density in conjunction with fairly normal bone contour
104What is anencephaly?
Congenital absence of the cranial vault
105What is aneurysmal bone cyst?
A solitary benign osteoplastic serum or blood-filled lesion of the bone
106What is anklosing spondylitis?
A form of rheumatoid arthritis of unknown cause that affects the spine in a progressive fashion, eventually fusing the spine into a rigid block of bone
107What is arthritis?
Inflammation in which lesions are confined to the joints
108What is bursitis?
inflammation of a bursa
109What is cancellous bone?
Bone that has a spongy, lattice-like structure filled with bone marrow
110What is a chondrosarcoma?
A malignant bone tumor composed of atypical cartilage
111What is clubfoot?
complex deformity of the ankle and foot
112What is compact bone?
Dense, outer portion of bone
113What is craniosynostosis?
Premature or early closure of the sutures of the skull
114What is craniotubular dysplasias?
An overgrowth of bone of the face and skull, resulting in sclerosis and major skeletal deformities
115what is development dysplasia of the HIP?
Abnormal tissue development
116What is the diaphysis?
Shaft of a long bone
117what is dipole?
The spongy bone tissue found between the two tables of the cranial bones
118What is enchondroma?
A benign growth of cartilage arising in the metaphysis of a bone
119what is epiphysis?
An ossification or growth center in the bones of children
120What is Escherichia coli?
A gram-negative bacterium found in the large intestine that may produce a toxin causing intestinal illness
121what is Ewing sarcoma?
A primary malignant bone tumor arising in medullary tissue, occurring more often in cylindric bones
122what is exostoses?
A benign bone growth projecting outward from the bony cortex
123what is fibrous dysplasia?
A bone disorder in which fibrous tissue develops instead of bone tissue
124What is a ganglion?
Cystic swelling that develops in connection with a tendon sheath, usually on the back of the wrist
125what is a giant cell tumor?
A neoplastic growth of the skeletal system consisting of numerous multinucleated osteoclastic giant cells
126 also known as an osteoclastoma
127What is gouty arthritis?
An inherited metabolic disorder with excess amounts of uric acid produced and deposited in the joint and adjacent bone, most commonly in the metatarsophalangeal joint of the great toe
128what is hyperostosis frontalis interna?
A thickening of the inner side of the frontal bone as a result of a benign tumor
129What is involucrum?
A shell or sheath of new supporting bone laid down by periosteum around a sequestrum of necrosed bone
130What is juvenile idiopathic arthritis?
A form of arthritis causing joint inflammation and stiffness affecting individuals under 16 years of age
131What is Klippel-Feil syndrome?
A congenital condition resulting in fusion of the cervical spine
132What is the medullary cavity?
Inner spongy or cancellous portion of a long bone where bone marrow is produced
133What is the metaphysis?
The growing portion of bone
134What is osteoarthritis?
degenerative joint disease
135What is osteoblastoma?
tumors of the bone arising from osteoblasts
136What is osteoblast?
bone forming cells
137What is osteochondroma?
a primary benign bone tumor characterized by overgrowth of cartilage and bone near end of the bone at the growth plate.
138What is osteoclastoma?
Giant cell tumor
139What is osteoclasts?
cells that are associated with absorption and removal of the bone
140What is osteogenesis imperfecta?
brittle bone disease
141What is osteoma?
benign tumor of bone
142What is osteomyelitis?
infection of the bone
143What is osteopetrosis also known as?
marble bone disease
144what is osteophytes?
bone spurs
146What is the periosteum?
the tough membrane that covers the outside of the bone
147What is polydactyly?
extra fingers or toes
148What is Pott's disease?
tuberculosis of the spine
149What is psoriatic arthritis?
joint pain and stiffness associated with psoriasis
150what is reactive arthritis?
Joint pain and swelling triggered by an infection in another part of the body
151What is rheumatoid arthritis?
a chronic progressive disease causing inflammation in the joints and resulting in painful deformity and immobility, especially in the fingers, wrists, feet, and ankles.
152What is Scheuermann's disease?
a growth condition causing kyphosis of the thoracic spine
153What is scoliosis?
lateral curvature of the spine
154What is a sequestrum?
piece of dead bone
155what is simple unicameral bone cyst
a benign fluid-filled bone neoplasm
156What is spina bifida?
A birth defect in which a developing baby's spinal cord fails to develop properly.
157What is Staphylococcus aureus?
a common bacteria found on the skin
158What is syndactyly?
fused digits
159What is tendonitis?
inflammation of a tendon
160What is tenosynovitis?
inflammation of a tendon sheath
161What is trabeculae?
the spongy substance found within a bone, it gives a characteristic appearance to bone details
162what is trabecular pattern?
The arrangement of supportive strands of connective tissue of the alveolar bone in relation to the bone marrow spaces within the cancellous bone
163what is transitional vertebra?
a vertebra that assumes the characteristics of the vertebrae on each side of a major spine division.
164what is tuberculosis of the bone and joint?
any of the infectious diseases of man and animals caused by mycobacterium tuberculosis, generally affecting the lungs.