1whats haemoglobin
Made up of 4 polypeptide chains with each having a haem group and these have an iron ion which can bind with one oxygen
2Affinity?
how likely haemoglobin is to load with oxygen
3Loading(association)
binding of oxygen to haemoglobin
4Unloading(dissociating)
releasing oxygen
5Oxyhaemoglobin dissociation curve?
Expresses that oxygen is loaded in regions with high partial pressure of oxygen and is unloaded in regions with low partial pressure
6Area with high partial pressure and low partial pressure?
High:Lungs
Low: respiring tissues
7co-operative binding?
the binding of the first oxygen changes shape of haemoglobin making it easier for other oxygens to bind
8The bohr effect?
high carbon dioxide concentration causes curve to shift to the right since affinity decreases as acidic CO2 changes shape of haemoglobin slightly
9Different animals have different affinities in order to adapt to their surroundings eg:
Foetal and llamas: Have higher affinity
10myoglobin?.
similiar to haemoglobin but its one haem group has very high affinity and acts as 02 reserve for muscles
11Double circulatory system meaning?
blood passes through heart twice in one cycle. Once oxygenated and once deoxygenated
12why double?
To control blood pressure:
In lungs pressure decreases to prevent damage to capillaries and give more time for gas exchange.
Oxygenated blood needs higher pressure to go around the body quicker
13Cardiac muscle?
Thick muscle in heart that is:
myogenic - can contract/ relax without any stimulation
Doesnt fatigue if it has oxygen
14Coronary artieries
Supplies cardiac muscles with oxygenated blood
154 chambers
Left/ right atrium: Thinner elastic walls
Left/ right ventricle: Thicker walls to create pressure but left is thicker
16Veins?(superior vena cava top and inferior bottom)
Vena cava - carries deoxygenated blood from body to right atrium
Pulmonary vein: Carries oxygenated blood from lungs to left atrium
17Arteires
Aorta: carries oxygenated blood from left ventricle to rest body
Pulmonary artery: carries deoxygenated blood from right ventricle to lungs
18semi lunar valve and AV valves?
pulmonary valve: To pulmonary artery
aortic valve: To aorta
Tricuspid: right side of heart (biology wise)
Bicuspid: left side of heart (biology wise)
19septum
Wall that separates the deoxygenated blood from the oxygenated blood
20Systole and Diastole meaning?
SYSTOLE = Period of contraction
DIASTOLE = Period of relaxation
21Diastole?
-Blood enters RIGHT atrium increasing its volume and pressure
-Atrium and ventricles relax
22Atrial systole stages?
1)Walls of atria contract
2)This increases its pressure and decreases volume
3)Atriums pressure now higher than ventricles
4)AV valves open and blood moves into ventricles
23Ventricular systole?
1)Walls of ventricle contract
2)This increases its pressure extremely and decreases volume
3)AV valves close and semi lunar valves opens
4)Blood moves into arteries and out of heart
24Whats cardiac output?
Volume of blood that leaves ventricle per minute
Cardiac output = heart rate X stroke volume
25what does this graph show?
26what is mass flow
Movement of fluid from region of high pressure to region of low pressure. Passive
27What is tissue fluid
Liquid surrounding cells and is bridge between blood and cells
Contains water,glucose, oxygen, ions etc
28Ultrafiltration?
Process of which small molecules pass out of arterial end by high hydrostic pressure from high water potential to low water potential. Large molecules stay.
29Reabsorption? (tissue fluid)
Pressure is low in venous end and has low water potential due to proteins(etc) so tissue fluid which now has waste products diffuses back in capillaries
30What happeneds to left over tissue fluid
Excess tissue fluid is absorbed by lymphatic vessels which returns it back to circulatory system to the veins
31whats oedema
swelling caused by excess tissue fluid
32How can it occur?
Malnutrition(decrease protein conc)
Increased blood pressure
Damaged capillaries(increase protein conc)
Blockage of lymph vessels
33What is transpiration?
evaporation of water from plant leaves
34What affects transpiration
Humidity
Air flow
Light intensity
Temperature
35COHESION TENSION THEORY
Theory of how water can move from roots to leaves due to COHESION,ADHESION AND ROOT PRESSURE
36Movement of water up xylem
1)Water evaporates out of stomata decreasing pressure
2)This leads to more water pulling up
3)Since they're cohesive it forms a column of water in xylem
4)Water also adheres to xylem helping to pull upwards and this creates tension
37Phloem tissue components:
Sieve tube elements
Companion cells- provide ATP
38Translocation stages?
1)Source cell has lots of sucrose so FD into companion cell
2)H+ is actively transported into cell walls by companion cell
3)Forms gradient so H+ diffuse by co transporter which also transports sucrose into sieve tube elements
4)Increase of sucrose in sieve tube decreases WP and so water enters from xylem
5)This increases hydrostatic pressure pushing sucrose down
6)Sucrose actively transported into sink cell, decreasing WP
7)Results in osmosis of some water in sink cell decreasing hydrostatic pressure
39Arterioles?
Smaller than arteries and connect arteries to capillaries
40Capillaries?
Connect arterioles to veins
41Arteries structure?
Thick muscle layer so can constrict/dilate to control volume of blood flow(WITHSTAND HIGH BLOOD PRESSURE)
Thick elastic walls compared to veins to maintain high blood pressure so blood can reach all of the body BY stretching and recoiling(bounce back)
No valves

42Veins structure?
Thin muscle layer so can't control blood flow(as they carry blood away from tissues)
Thin elastic walls as blood pressure is alot lower
Has valves
43Capillaries structure?
No muscle and elastic layer so thin membrane so fast diffusion
Lots of them and branches so high SA
Narrow lumen barely fitting RBC lowering blood flow
44Arterioles? Strucute
Thicker muscle layer(compared to arteries) to restrict blood flow more to the capillaries
Thinner elastic layer as pressure is lower
No valves