1What is this picture an example of?

molds
2What is this picture an example of?

Yeast
3What are the characteristics of molds?
MULTICELLULAR filaments, with hyphae
4What are the characteristics of yeast?
single cell that grows / reproduces through budding
5What is Mycelium?
matlike network of hyphae
6What is this called?

septate hyphae
7What are the 5 kinds of vegetative hyphae?
favic chandelier / antler hyphae
nodular hyphae
pectinate body hyphae
spiral (coiled) hyphae
racquet hyphae
8What kind of hyphae is this?

favic chandelier / antler hyphae
9What kind of hyphae is this?

nodular hyphae
10What kind of hyphae is this?

pectinate body hyphae
11What kind of hyphae is this?

spiral (coiled) hyphae
12What kind of hyphae is this?

racquet hyphae
13What kind of hyphae is this?

coenocytic (nonseptate) hyphae
14What are pseudohyphae?
marked by constrictions, not septate
15What are fungal spores?
means of fungal reproduction;
asexual or sexual
major source of fungal infection
16What are the 3 kinds of sexual spores?
basidiospore
ascospore
zygospore
17How are asexual spores formed?
through mitosis
18What are the 5 kinds of asexual spores?
(SCCAB)
sporangiospore
conidiospore
chlamydospore
arthrospore
blastospore
19What kind of spore is this?

sporangiospore
20What are 3 examples of sporangiospore?
(RAM)
rhizopus
mucor
absidia (lictheimia)
21What kind of spore is this?

uniserate conidiospore
22What is letter F?

Rhizoids
23What kind of spore is this?

biserate conidiospore
24What does conidiospore have that sporangiospore usually does not?
septate hyphae
25What are 2 examples of conidiospores?
penicillum
aspergillus
26What kind of spore is this?

arthrospore
27What are 3 examples of arthrospores?
trichosporon
geotrichum
coccidioides immitus
28What kind of spore is this?

chlamydospore
29What is an example of chlamydospore?
Candida albicans
30What kind of spore is this?

blastospore
31What are blastospores a result of?
budding of a yeast (Asexual rerproduction)
32Label A and B

A-microconidium
B-macroconidium
33What are macroconididia?
large asexual structures divided into cells with transverse septa
34What are microconidia?
small asexual strcutures
35Label A and B dermatophytes

A-macroconidia macrosporum
B-microcondia microsporum
36Label A and B dermatophytes

A-macroconidia trichophyton
B-microcondia trichophyton
37Label this structure

macrocondia epidermophyton
38What kind of infection does superficial / cutaneous mycoses : dematophytosis do?
outermost layers of skin or hair because they love keratin
39How does ringworm present?
circular rash
40What causes ringworm?
dermatophytes
41What are the dermatophytes that cause ringworm?
trichophyton
microsporum
epidermophyton
42What is ringworm also known as?
tinea
dermatophytosis
43What are the 4 ways fungi can invade the hair shaft?
ectothrix
ecto-endothrix
endothrix
favus
44What kind of hair invasion is shown?

ectothrix
45What kind of hair invasion is shown?

ecto-endothrix
46What kind of hair invasion is shown?

endothrix
47What kind of hair invasion is shown?

favus
48What hair invasion would show UV light negative?
endothrix (?)
49What is favus hair invasion?
honeycomb infection;
clusters of hyphae at teh base with air spaces in hair shaft
yellow crust around hair shaft
50Where does Tinea capitis affect?
head
(scalp ringworm)
51What is a known species of scalp ringworm?
T. tonsurans (most common in US)
52What causes favus?
T. schoenleinii
53What is favus?
severe form of scalp ringworm
54What is ringworm of the feet?
Tinea pedis
55What is Tinea pedis associated with?
athelete's foot
56Where does Tinea manuum affect?
hands!
manuum = thumb
57What kind of ringworm is tinea manuum?
ringworm of the hands
58What species primarily causes Tinea manuum?
trichophyton rubrum
59What is the common clinical presentation of ringworm of the hands?
two foot, one hand syndrome (acquired when picking at athlete's foot)
60What does cruris in Tinea cruris refer to?
cruris = leg
61What is ringowrm of the groin / pubic caused by?
trichophyton rubrum
62What is another name for Tinea cruris (ringworm of the groin / pubic?
jock itch
63What does barbae in Tinea barbae mean?
beard
64What is another name for Tinea barbae (beard ringworm) infection?
Barber's itch
65What does unguium in Tinea unguium mean?
nails
Tinea unguium = ringworm of the nails
66What is the the major cause of ringworm of the nail (Tinea unguium)?
onychomycosis (dermatophyte)
67What does corporis in Tinea corporis mean?
corporis = body
Tinea corporis = ringworm of the body
68What strain causes ringworm of the body / Tinea corporis?
T. rubrum
69What organism sporuting resembles 'bird on a wire'?
Trichophyton rubrum
70What kind of ringworm is trichophyton tonsurans?
scalp ringworm
71What causes 'black-dot' tinea capitis?
trichoypton tonsurans
due to hair breaking easily
72What can be seen in trichophyton tonsurans?
abundant microconidia, chlamydospores
73What causes microsporum canis?
zoophilic--cats, dogs, others
mostly by domestic cat
74Where can Microsporum gypseum be found?
geophillic--in contaminated soils
also in dogs, cats, and other animals exposed to dirt
75What does epidermophyton floccosum look like?
club shaped (beaver tail)
macroconidia
76What does Wood's Lamp ID?
ectothrix infections
77What are the main dermatophytes that fluoresce under UV light?
Microsporum spp.
78What is piedra translated to?
stone
79What is piedra?
superficial fungal infection of hair shaft that presents as small nodules stuck onto hair
80What organism causes Thrush?
Candida spp.
81What causes Tinea nigra?
superficial mycosis caused by Hortaea wernickii
82What organism resembles 'spaghetti and meatballs'?
Malassezia furfur
83What is M. furfur dependent on?
lipid-dependent
84What kind of pathogen is Malassezia furfur?
opportunistic
85What does subcutaneous mycoses involve?
muscle, lymph vessels, and connective / neighboring tissue
86What is another name for Mycetoma?
'Madura Foot'
87What are the two kinds of mycetoma?
eumycotic
actinomycotic
88What causes eumycotic mycetoma?
fungi
89What causes actinomycotic mycetoma?
bacteria
90What are the agents of eumycetoma?
Madurella (M. mycetomatis, M. grisea)
Pseudallescheria boydii
Leptosphaeria spp.
91What are the agents of actinomycetoma?
Nocardia
Streptomyces
Actinomyces
92What should be collected when mycetoma is considered?
grains / granules of the sinus discharge that contain colonies of the causative organism
93What does black grain eumycetoma indicate?
madurella complex
94What does white grain mycetoma indicate?
Pseudallescheria boydii
95Which is more dangerous, white or black grain mycetoma?
white grain
96What organism uses the partial acid fast stain?
Nocardia
97What can be seen in Nocardia mycetoma lesions?
sulfur granules
98What is another name for Lymphocutaneous sporotrichosis infection?
Rose gardener's Disease
99What kind of fungus is Lymphocutaneous sporotrichosis?
DIMORPHIC fungus: Sporothrix schenckii
100What are the two forms of lymphocutaneous sporotrichosis?
mold form and yeast form
101What temperature do you see mold form of L. sporotrichosis?
25C
102What temp do you see yeast form of L. sporotrichosis?
37C
103What does 'hyalo' in hyalophomycosis mean?
hyalo=glass
due to colorless hyaline, nonpigmented, or lightly colored mold with septate hyphae in tissue
104What are the common causative agents in hyalophomycosis?
acremonium
fusarium (mycotoxins on food)
geotrichum (ceral / dairy products)
paecilomyces (eye infections)
scedosporium
105What does chromo in chromoblastomycosis mean?
chromo = color
106What causes chromobastomycosis / chromomycosis?
caused by several species of melanized fungi that produce a dark pigment
107What are the common causative agents of chromobastomycosis?
Fonsecaea spp.
Phialophora spp.
Cladosporium spp.
108What does 'phaeo' in phaeohyphomycosis mean?
phaeo = gray
109What causes phaeohyphomycosis infections?
darkly pigmented dermatiaceous fungi
110What are the common causative agents of phaeohyphomycosis?
Cladosporium
Exophiala
Wangiella
Cladophialophora
Bipolaris
111What causes subcutaneous zygomycosis / mycormycosis?
caused by a group pof fungi -- mucormycetes
112What organisms are related to subcutaenous zygomycosis / mucormycosis?
Mucor
Rhizopus
Absidia (Lictheimia)
113How can you tell the difference between zygomucosis / mucormycosis?
Looking at roots
114What organinsm is shown?

Mucor
115What organinsm is shown?

Rhizopus
116What organinsm is shown?

Absidia (Lichtheimia)
117What kind of pathogens are Dimorphic Fungal Pathogens?
primary systematic pathogens (causing infection in normal and immunocompromised people)
118What temps do dimorphic species take mold form?
25C-30C
119What temps do dimorphic species take yeast form?
37C
120What are the dimorphic fungi?
Histoplasma capsulatum
Blastomyces dermatiditis
Paracoccidiodes braziliensis
Coccidiodes immitis
Penicillum (Talaromyces) marneffei
Sporothrix schenkii
121What dimorphic species is shown?

Histoplasma capsulatum
122What dimorphic species is shown?

Blastomyces dermatiditis
123What dimorphic species is shown?

Paracoccidiodes braziliensis
124What dimorphic species is shown?

Coccidiodes immitis
125What dimorphic species is shown?

Penicillum (Talaromyces) marneffei
126What dimorphic species is shown?

Histoplasma capsulatum
127Where can you get exposed to Histoplasma capsulatum?
bird droppings and bat guano
128What dimorphic species is shown?

Blastomyces dermatiditis
129What species has a yeast form that resembles a 'captain's wheel'?
Paracoccidiodes braziliensis
130What dimorphic species is shown?

Paracoccidiodes braziliensis
131What dimorphic species is shown?

Coccidiodes immitis
132What kind of form does Coccidioides immitis take?
arthroconidia
133What infection does coccidioidomycosis lead to?
San Joaquin Valley Fever
VERY DANGEROUS!
134What species is shown?

Coccidioides immitis
135What species is shown?

Penicillum marneffei
136What is unique of the yeast form in Penicillium (talaromyces) marneffei?
Yeast form has internal transverse / septum crosswalls, no budding yeast
137What is the name of Sprothrix schenkii infection?
Sporotrichosis
"Rose Gardener's Disease"
138What are the 3 kinds of Rose Gardener's Disease?
Cutaneous (skin) sporotrichosis
Pulmonary (lung) sporotrichosis
Disseminated sporotrichosis
139What is the organism shown?

Sporothrix schenkii
140What are the 4 kinds of opportunistic fungi?
Candida
Aspergillus
Cryptococcus
Mucor
141What are the 2 main candida species?
C. albicans
C. auris
142What is the most common candida isolated?
C. albicans
143What candida is an emerging public health threat?
C. auris
144What organism is shown?

Candida spp.
145Why is Candida auris an emerging threat?
multidrug resistant yeast with outbreaks in long term care facilities and hospitals worldwide with a high mortality rate
146What kind of pathogen is Aspergillus spp.?
Opportunistic!
147What organism is shown?

Aspergillus spp.
148What is the difference between the right and left?

left is uniserate while the right is biserate
149What does biserate phialide contain?
metula (close to vesicle) and the phialide
(whereas uniseriate only containes phialide and no metula)
150How can you tell the difference between A. fumigatus, A. niger, and A. flavus
color
Aspergillus fumigatus = green
A. niger = black
A. flavus = brown
151Where can cryptococcus neoformans be found?
in the lungs and brain
inhaled from the environment
152What is C. neoformans associated with?
pigeon droppings, decaying wood, soil, tree hollows
153What is the common specimen used when testing for C. neoformans?
CSF
154What is the stain for C. neoformans?
india ink (highlights the protective capsule around organism)
155What organism is shown?

Cryptococcus neoformans
156Why do physicians want antifungal susceptibility testing?
fungal infection is invasive, when acquired drug resistance is suspected, or when the pt is unexpectedly failing therapy
157What agar is good for cryptococcus?
bird seed agar
(also remember cryptococcus = india ink stain)
158What is the purpose of india ink?
to identify encapsulated yeast