BIOL 431 - LEC 6
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1
What are the 2 factors that effect blood flow?
pressure differences and resistance
2
What are the 3 peripheral resistances?
blood viscosity, blood vessel length, blood vessel diameter
3
How is blood flow (F) calculated?
Differnce in blood pressure over peripheral resistance
4
What does pulsitile mean?
surges in pressure that are constant
5
What is systole and what’s the avg systolic pressure?
systole is the state of contraction and avg os 120mmHg
6
What is diastole and what’s the avg pressure?
State of relaxation 70-80mmHg
7
What is pulse pressure? and what is the equation?
throbbing in artery during systole, avg 30-40mmHg, (systolic - diastolic)
8
What is arteriosclerosis?
artery wall looses ability to stretch causing increase in pressure
9
What is Mean artieral pressure (MAP)?and the equation?
Avg bp of heart, diastolic + (pulse pressure/3)
10
What is the average pressure of the capillary ? and a fact?
40-20mmHg, highly permeable,
11
Where are vasomotors found and what do they do?
found in medulla, increase sympathetic function > vasoconstriction > increased BP
12
What are the two vasomotor modifications?
Barorecpetors and chemoreceptors
13
What is the function of Baroreceptors?
found in carotid sinus and aortich arch, • vasodilation and decreased HR > decreasing pressure > vasoconstriction and stimulation of cardioacceleratory centers > increased pressure
14
What is the function of chemoreceptors ?
monitors changes in o2,pH, co2. send sig to medulla > increase CO > vasoconstriction > decreases o2 > increases pH > increase HR > Increase BP > blood returns to lungs faster
15
What are some short term chemicals we use to maintain BP?
adrenal medulla hormones, atrial natruistic peptide, antidiurteic hormone, ETOH (ethanol)
16
What does the adrenal medulla hormone do?
• Increase stress > release of norepinephrine (NE) and epinephrine into the blood > Stimulates the fight or flight response > NE > vasoconstriction
• Epinephrine > increased CO
• Epinephrine > increased CO
17
What does atrial natriuretic peptide do ? (ANP)
stimulates kidney to excrete more water & Na > drop in fluid vol > decreased BP
18
what does antidiretic hormone do? (ADH)
stim kidney to conserve water > increased fluid retention > Raises BP
19
What does ETOH stand for and what does it do?
Ethanol, inhibits release of ADH > vasodilation > increased fluid loss @ kidney > decreases volume > decreases BP
20
What is our long term way to regulate BP?
kidneys, 