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temporal lobe
studying temporal lobe = studying memory

memory is in medial temporal lobe
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long term memory location
long term memory associated with amygdala and hippocampus
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patient HM
removal bilateral medial temporal lobe

including hippocampus and amygdala besides others
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consequences for patient HM
impossible to store and consolidate new information ( anterograde amnesia )

impaired in spatial and topographic learning and events that took place around him

able to learn new motor skills by repetition

long term memory pre
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operative events were intact ( time dependent amnesia )
short term memory was intact
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amnesia
= the lost of existing memories or the inability of forming new memories
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cauase of amnesia
it stems form an event or accident that causes memory loss
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types of amnesia
1. Anterorgade amnesia
2. Retrograde amnesia
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anterograde amnesia
inability to make new memories
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retrograde amnesia
loss of memory before the event

time dependent : more recent events more likley to be lost
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short term memory
sensory

motor

cognitive
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working memory
working memory is not always short term memory
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long term memory types
1. explicit
2. implicit
3. emotional
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explicit memory
conscious

1. episodic
2. semantic
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episodic memory
personal : what i had this morning for breakfast
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semantic memory
facts : who is the second priminister
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implicit memory
unconscious : skills , habits , priming , conditioning
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emotional memory
conscious and unconscious ) : attraction, avoidance fear
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learning episodic memory
new learning in general like learning for neurospychology
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regions for sematic memeory
includes frontal and temporal regions ( distinct form episodic )

more lateral temporal lobe in left hemisphere

more repetioiton = more lateralised
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episodic memory regions
hippocampus is essential ( medial temporal lobe )

after reading the same text over and over again → transported to lateral temporal cortex ( location of semantic memory )
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importance structures
in explicit memory the temporal lobe structures plays one of the most important roles

to remember : that medial thalamus plays a role as well
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most important structure inprocedual memory
the basal ganglia
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how we test implict memory
implicit memory can be seen in experiments such as mirror tests

patient HM was able to master a skill the more he was rehersing it

he could not remeber the task however he did it faster and faster each time
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emotional memory
amygdala is the most important part of the circuit
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**Prefrontal cortex in memory**
participates in autobiographical memory

there is a pattern of hemispheric asymmetry between memory encodic and retrieval
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HERA
**hemispheric encoding and retrieval asymmetry**
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left HERA
more encoding of semantic than retrieving it

more encoding of episodic than retrieving it
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right HERA
more retrieval of episodic memory
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other important areas
left oribitofrontal cortex active during memory encoding of words/series of words

these regions do not retrieve the information

right dorsal prefrontal cortex and posterioir parietal cortex in both hemispheres are activated in retrieval
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**Korsakoff syndrome**
esion : dorsomedial part thalamus + frontal

also called diecephalic amnesia
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cause of Karsokoff syndrome
prolonged excessive alcohol abuse , low vit B1 deficit
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symptoms
anterograde / retrograde amnesia

confabulations

coversation : little informative

lack of insight

apathy/ indiference
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Dorsal and ventral stream in STM
different short term areas take part in STM

cells that code spatial vision are located in area 8 (premotor cortex)

cells that code object recognition are located in area 9 and 46 of dlPFC >
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central executive ("slave systems ")
1. phonological loop ( verbal and auditory information )
2. visuospatial sketchpad (visual and spatial information )
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role of central executive
attentional controller (distributes attention across tasks )

coordination of complex cognitive operations ( e.g. 12 x 27)
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Kluver Bucy syndrome
cause ( bilateral anterioir temporal lobe lesion )

symptoms

visual agnosia

changes in dietary hbits ( eats everything )

reaction to every stimulus

hyperoral behaviour (puts everything in mouth )

loss of feaar

increase in auto erotic, homo eroticor eteroerotic activity
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