Bio 001 Exam 3

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1
ONE chromosome (circular) and not wound around protiens, NO organelles, ALL single celled organisms
prokaryotic cells
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MULTIPLE chromosomes (linear) and wrapped around protiens, chromosome in NUCLEUS, single celled OR multicellular organisms
eukaryotic cells
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Reproduction (ALL organisms), growth and repair (ONLY multicellular eukaryotes)
cell division purpose
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ONE parent produces genetically identical offspring (same DNA sequence as parent)
asexual reproduction
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fusion of egg and sperm (gametes), genetically unique offspring
sexual reproduction
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2 genetically identical offspring: 1. DNA replication starts 2. Chromosome copies are pulled to opposite sides of dividing cell 3. Cell splits (physically divides)
prokaryotic cell division
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ALL chromosomes in a cell: ALL cells of a multicellular organisms have the same sets of genes, different chromosomes have different sets of genes
eukaryotic genome
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position of gene on a chromosome
locus
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ONE set of chromosomes; gametes (egg or sperm), cells of some eukaryotes (eg fungi, mosses)
haploid cell
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TWO sets of chromosomes, 2 alleles for every gene; single cell eukaryotes and body cells of multicellular organisms
diploid cell
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a pair of chromosomes with the same sets of genes, seperated in meiosis but NOT mitosis
homologous chromosomes
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different versions of the same gene
allele
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cell has the same number of different chromosomes, but TWICE as much DNA
after DNA replication
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duplicate copies of an individual chromosome, generated by DNA replication (ONLY exist in pairs)
sister chromatids
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chromatids of homologous chromosome pair that are NOT sisters (one from each of the homologous chromosomes), alleles can be the same of different (1 copy of each of the 2 homologous chromosomes)
nonsister chromatids
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2 genetically identical daughter cells, parent cell can be haploid or diploid; purpose- growth and repair of multicellular organisms, asexual reprodiction
eukaryotic mitosis
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4 genetically different haplod daughter cells, MUST be diploid parent cell; purpose- formation of eggs and sperm for sexual reproduction
eukaryotic meiosis
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allows chromosomes to be distributed; sister chromatids stay attached, allows them to be distributed to different daughter cells; mitotic spindle forms- fibers exten from each ond of the cell
chromosomes condense
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spindle fibers attach to chromosomes- sister chromatids attach to fibers from opposite sies of the cell so sister chromatids distributed to different daughter cells
nuclear envelope breaks down
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line up chromosomes
spindle fibers
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seperated, transported by spindle fibers
sister chromatids
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forms around chromosomes at each end
new nuclear envelopes
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cell pinched into 2 seperate cells by ring of fibers
cytokinesis
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uncontrollable cell division due to mutations in genes that contain information for protiens that promote or prevent cell division; mutations in body cell CANNOT be passed to next generation; mutations in gametes CAN be passed to next generation - offspring have increased risk but need additional mutations to arise
cancer
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go from 2 sets of chromosomes (diploid) to one set of chromosomes (haploid)
divides sets of chromosomes
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done before meiosis I
DNA replication
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chromosomes condense, spindle forms, nuclear memebrane breaks down
homologous chromosomes pair up
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homologous chromosomes swap pieces of DNA, CAN occur
crossing over
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from opposite sides, get attached to one of each of homologous chromosomes
3. Eukaryotic meiosis
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pairs linf up in middle of cell - each pair up independently of other pairs
independent orientation
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pulled by spindle fibers to opposite sides of cell
homologous chromosomes
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generates 2 cells - haploid that have replicated chromosomes
cytokinesis
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similar to mitosis, 4 genetically unique haplod cells from sister chromatids seperately
meiosis II
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DIFFERENCES IN ALLELES of homologous chromosomes, INDEPENDENT ORIENTATION of homologous chromosomes in meiosis I, CROSSING OVER in meiosis II
causes of genetic differences
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study of how traits if individual are passed from parent to offspring
inheritance (genetics)
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differences in the information (DNA) required to create and matinain cells
genetic variation
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physical or functional feature that can be inherited (influenced by genes) - like genes
character
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variants of a character - like allele
trait
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combination of alleles
genotype
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combination of traits (physical or functional)
phenotype
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generates different allele combos for genes of DIFFERENT chromosomes, how one pair of homologous chromosomes line up does NOT affect other pairs
independent orientation
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can generate different allele combos on the SAME chromosome, paired up homologous chromosomes can swap corresponding pieces of DNA (trade pieces with the same genes)
crossing over
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which specific egg is fertilized, patterns of inheritence (mendels laws)
random fertilization
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many traits follow specific patterns of inheritence
mendel
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traits are primarily determinded by genes, genes are located on chromosomes, passing of chromosomes from one generation to the next helps explain patterns of inheritance
sutton and boveri
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some organisms have chromosomes that differ between sexes
stevens
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inheritence patterns of some traits are directly linked to organisms sex
morgan
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genes located on chromosomes common to males and females (autosomes); mendelian and nonmendelian traits
autosomal genes
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determined by ONE autosomal gene with only 2 different alleles, one trait dominates the other when 2 different alleles are present
mendilian traits
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genes located on sex chromosome (have genes that determine sex)
sex linked genes
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SAME alleles for a gene
homozygous
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DIFFERENT alleles for a gene
heterozygous
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combos of alleles from egg and sperm
offspring genotype possibilities
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determine probability of any offspring (independent from eachother)
punnett squares
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LARGE sample sizes closer to true probabilities
number of offspring
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of homologous chromosomes is why different allele combos are possible for genes on different chromsomes
independent orientation
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an organism chosen to study specific biological phenomenon due to beneficial features: inexpensive and easy to grow, many different varieties with easily distinguishable traits for various characters, matings can be controlled, short reproductive time, produce lots of offspring
model organisms
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eggs fertilized by sperm from SAME plant
self fertilization
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produces eggs that can be fertilized by sperm from pollen
female organ
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produces polled that contains sperm
male organ
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ALL offspring of self fertilization always have the same traits as parent (a particular trait, not all traits), ALWAYS HOMOZYGOUS
true breeding
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a controlled mating between 2 individuals
cross
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analyze inheritenence between ONE character
monohybrid cross
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analyze inheritence in TWO characters
dihybrid cross
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phenotype observed for heterozygotes (NOT more common of beneficial)
dominant trait
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allele that corresponds to a dominant trait (NOT more common of beneficial)
dominant allele
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individual MUST have TWO alleles that correspond to the recessive trait to show the trait
recessive trait
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allele that corresponds to the recessive trait
recessive allele
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one allele completely masks the other (look at particular trait)
complete dominance
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FOUR different gamete genotypes, independent orientation results in all possible combos of alleles
different chromosome scenario
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TWO different gamete genotypes; If no crossing over between the genes, alleles on the same chromosome will stay "packaged" together
same chromsome scenario
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female
XX
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male
XY
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genes on the X chromosome
X linked genes
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genes on the Y chromosome
Y linked genes
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nucleus of cell from male that forms sperm
gametes with X and Y
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nucleus of cell from female that forms egg
gametes with X only
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during development, one X chromsome is inactivated in each cell (random process)
X inactivation
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most genes have more than 2 possible alleles
multiple alleles
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heterozygotes have intermediate phenotype
incomplete dominance
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heterozygotes show both traits
codominance
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a character is determined by more than one gene, often show new F2 phenotypes or a continuum of phenotypes
polygenic inheritance
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one gene affects more than one character, effects on different characters can be related or have no apparent connecion
pleiotropy
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limited understanding of disease phenotypes
limited data
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must be homozygous for disease allele to be affected, heterozygous carriers (have disease allele but not the disease), heterozygotes are partially affect in some diseases (eg alleles show incomplete dominance)
autosomal recessive
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only need ONE copy of the disease allele to be affected, homozygous dominant and heterozygous are equally affected
autosomal dominant
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females must be homozygous for the disease allele to be affected, ALL males with disease allele are affected
X linked recessive
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