1ONE chromosome (circular) and not wound around protiens, NO organelles, ALL single celled organisms
prokaryotic cells
2MULTIPLE chromosomes (linear) and wrapped around protiens, chromosome in NUCLEUS, single celled OR multicellular organisms
eukaryotic cells
3Reproduction (ALL organisms), growth and repair (ONLY multicellular eukaryotes)
cell division purpose
4ONE parent produces genetically identical offspring (same DNA sequence as parent)
asexual reproduction
5fusion of egg and sperm (gametes), genetically unique offspring
sexual reproduction
62 genetically identical offspring: 1. DNA replication starts 2. Chromosome copies are pulled to opposite sides of dividing cell 3. Cell splits (physically divides)
prokaryotic cell division
7ALL chromosomes in a cell: ALL cells of a multicellular organisms have the same sets of genes, different chromosomes have different sets of genes
eukaryotic genome
8position of gene on a chromosome
locus
9ONE set of chromosomes; gametes (egg or sperm), cells of some eukaryotes (eg fungi, mosses)
haploid cell
10TWO sets of chromosomes, 2 alleles for every gene; single cell eukaryotes and body cells of multicellular organisms
diploid cell
11a pair of chromosomes with the same sets of genes, seperated in meiosis but NOT mitosis
homologous chromosomes
12different versions of the same gene
allele
13cell has the same number of different chromosomes, but TWICE as much DNA
after DNA replication
14duplicate copies of an individual chromosome, generated by DNA replication (ONLY exist in pairs)
sister chromatids
15chromatids of homologous chromosome pair that are NOT sisters (one from each of the homologous chromosomes), alleles can be the same of different (1 copy of each of the 2 homologous chromosomes)
nonsister chromatids
162 genetically identical daughter cells, parent cell can be haploid or diploid; purpose- growth and repair of multicellular organisms, asexual reprodiction
eukaryotic mitosis
174 genetically different haplod daughter cells, MUST be diploid parent cell; purpose- formation of eggs and sperm for sexual reproduction
eukaryotic meiosis
18allows chromosomes to be distributed; sister chromatids stay attached, allows them to be distributed to different daughter cells; mitotic spindle forms- fibers exten from each ond of the cell
chromosomes condense
19spindle fibers attach to chromosomes- sister chromatids attach to fibers from opposite sies of the cell so sister chromatids distributed to different daughter cells
nuclear envelope breaks down
20line up chromosomes
spindle fibers
21seperated, transported by spindle fibers
sister chromatids
22forms around chromosomes at each end
new nuclear envelopes
23cell pinched into 2 seperate cells by ring of fibers
cytokinesis
24uncontrollable cell division due to mutations in genes that contain information for protiens that promote or prevent cell division; mutations in body cell CANNOT be passed to next generation; mutations in gametes CAN be passed to next generation - offspring have increased risk but need additional mutations to arise
cancer
25go from 2 sets of chromosomes (diploid) to one set of chromosomes (haploid)
divides sets of chromosomes
26done before meiosis I
DNA replication
27chromosomes condense, spindle forms, nuclear memebrane breaks down
homologous chromosomes pair up
28homologous chromosomes swap pieces of DNA, CAN occur
crossing over
29from opposite sides, get attached to one of each of homologous chromosomes
3. Eukaryotic meiosis
30pairs linf up in middle of cell - each pair up independently of other pairs
independent orientation
31pulled by spindle fibers to opposite sides of cell
homologous chromosomes
32generates 2 cells - haploid that have replicated chromosomes
cytokinesis
33similar to mitosis, 4 genetically unique haplod cells from sister chromatids seperately
meiosis II
34DIFFERENCES IN ALLELES of homologous chromosomes, INDEPENDENT ORIENTATION of homologous chromosomes in meiosis I, CROSSING OVER in meiosis II
causes of genetic differences
35study of how traits if individual are passed from parent to offspring
inheritance (genetics)
36differences in the information (DNA) required to create and matinain cells
genetic variation
37physical or functional feature that can be inherited (influenced by genes) - like genes
character
38variants of a character - like allele
trait
39combination of alleles
genotype
40combination of traits (physical or functional)
phenotype
41generates different allele combos for genes of DIFFERENT chromosomes, how one pair of homologous chromosomes line up does NOT affect other pairs
independent orientation
42can generate different allele combos on the SAME chromosome, paired up homologous chromosomes can swap corresponding pieces of DNA (trade pieces with the same genes)
crossing over
43which specific egg is fertilized, patterns of inheritence (mendels laws)
random fertilization
44many traits follow specific patterns of inheritence
mendel
45traits are primarily determinded by genes, genes are located on chromosomes, passing of chromosomes from one generation to the next helps explain patterns of inheritance
sutton and boveri
46some organisms have chromosomes that differ between sexes
stevens
47inheritence patterns of some traits are directly linked to organisms sex
morgan
48genes located on chromosomes common to males and females (autosomes); mendelian and nonmendelian traits
autosomal genes
49determined by ONE autosomal gene with only 2 different alleles, one trait dominates the other when 2 different alleles are present
mendilian traits
50genes located on sex chromosome (have genes that determine sex)
sex linked genes
51SAME alleles for a gene
homozygous
52DIFFERENT alleles for a gene
heterozygous
53combos of alleles from egg and sperm
offspring genotype possibilities
54determine probability of any offspring (independent from eachother)
punnett squares
55LARGE sample sizes closer to true probabilities
number of offspring
56of homologous chromosomes is why different allele combos are possible for genes on different chromsomes
independent orientation
57an organism chosen to study specific biological phenomenon due to beneficial features: inexpensive and easy to grow, many different varieties with easily distinguishable traits for various characters, matings can be controlled, short reproductive time, produce lots of offspring
model organisms
58eggs fertilized by sperm from SAME plant
self fertilization
59produces eggs that can be fertilized by sperm from pollen
female organ
60produces polled that contains sperm
male organ
61ALL offspring of self fertilization always have the same traits as parent (a particular trait, not all traits), ALWAYS HOMOZYGOUS
true breeding
62a controlled mating between 2 individuals
cross
63analyze inheritenence between ONE character
monohybrid cross
64analyze inheritence in TWO characters
dihybrid cross
65phenotype observed for heterozygotes (NOT more common of beneficial)
dominant trait
66allele that corresponds to a dominant trait (NOT more common of beneficial)
dominant allele
67individual MUST have TWO alleles that correspond to the recessive trait to show the trait
recessive trait
68allele that corresponds to the recessive trait
recessive allele
69one allele completely masks the other (look at particular trait)
complete dominance
70FOUR different gamete genotypes, independent orientation results in all possible combos of alleles
different chromosome scenario
71TWO different gamete genotypes; If no crossing over between the genes, alleles on the same chromosome will stay "packaged" together
same chromsome scenario
74genes on the X chromosome
X linked genes
75genes on the Y chromosome
Y linked genes
76nucleus of cell from male that forms sperm
gametes with X and Y
77nucleus of cell from female that forms egg
gametes with X only
78during development, one X chromsome is inactivated in each cell (random process)
X inactivation
79most genes have more than 2 possible alleles
multiple alleles
80heterozygotes have intermediate phenotype
incomplete dominance
81heterozygotes show both traits
codominance
82a character is determined by more than one gene, often show new F2 phenotypes or a continuum of phenotypes
polygenic inheritance
83one gene affects more than one character, effects on different characters can be related or have no apparent connecion
pleiotropy
84limited understanding of disease phenotypes
limited data
85must be homozygous for disease allele to be affected, heterozygous carriers (have disease allele but not the disease), heterozygotes are partially affect in some diseases (eg alleles show incomplete dominance)
autosomal recessive
86only need ONE copy of the disease allele to be affected, homozygous dominant and heterozygous are equally affected
autosomal dominant
87females must be homozygous for the disease allele to be affected, ALL males with disease allele are affected
X linked recessive